Zobrazeno 1 - 10
of 1 312
pro vyhledávání: '"Colm J"'
Publikováno v:
British Journal of Biomedical Science, Vol 80 (2023)
Introduction: Biomedical Science distance learning courses offer flexibility in study while in employment. Asynchronous and self-learning approaches are common within such courses and often student-student interaction is limited. The aims of this stu
Externí odkaz:
https://doaj.org/article/53a663dae4524b72b5067bb66ba7c01e
Autor:
Barbara De Kegel, Colm J Ryan
Publikováno v:
Molecular Systems Biology, Vol 19, Iss 12, Pp n/a-n/a (2023)
Abstract Genomic instability is a hallmark of cancer, resulting in tumor genomes having large numbers of genetic aberrations, including homozygous deletions of protein coding genes. That tumor cells remain viable in the presence of such gene loss sug
Externí odkaz:
https://doaj.org/article/7ff233f2496043a2820614b2f23f86f0
Autor:
Hannes Jansson, Martin Cornillet, Dan Sun, Iva Filipovic, Christian Sturesson, Colm J. O’Rourke, Jesper B. Andersen, Niklas K. Björkström, Ernesto Sparrelid
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
IntroductionSystemic inflammatory markers have been validated as prognostic factors for patients with biliary tract cancer (BTC). The aim of this study was to evaluate specific immunologic prognostic markers and immune responses by analyzing preopera
Externí odkaz:
https://doaj.org/article/c3e7658b689242a6818b06ca97885cc3
Conditional Generative Adversarial Networks for Dynamic Control-Parameter Selection in Power Systems
Publikováno v:
IEEE Access, Vol 10, Pp 11236-11247 (2022)
This paper describes the novel application of conditional Generative Adversarial Networks (cGANs) for real-time stability region determination (SRD) in power systems. As the network configuration changes during the course of operation, the availabili
Externí odkaz:
https://doaj.org/article/4edd557625ec45b6b1064d344e58a634
Autor:
Aaron Barron, Samprikta Manna, Colm J. McElwain, Andrea Musumeci, Fergus P. McCarthy, Gerard W. O’Keeffe, Cathal M. McCarthy
Publikováno v:
Frontiers in Physiology, Vol 13 (2023)
Introduction: Pre-eclampsia (PE) is a common and serious hypertensive disorder of pregnancy, which affects 3%–5% of first-time pregnancies and is a leading cause of maternal and neonatal morbidity and mortality. Prenatal exposure to PE is associate
Externí odkaz:
https://doaj.org/article/e60778184f2b4945a7b85d82f97d86a3
Autor:
Anthime Flaus, Tahya Deddah, Anthonin Reilhac, Nicolas De Leiris, Marc Janier, Ines Merida, Thomas Grenier, Colm J. McGinnity, Alexander Hammers, Carole Lartizien, Nicolas Costes
Publikováno v:
Frontiers in Medicine, Vol 9 (2022)
Introduction[18F]fluorodeoxyglucose ([18F]FDG) brain PET is used clinically to detect small areas of decreased uptake associated with epileptogenic lesions, e.g., Focal Cortical Dysplasias (FCD) but its performance is limited due to spatial resolutio
Externí odkaz:
https://doaj.org/article/2c3d1170d99f4196a6368ca788decd8f
Publikováno v:
Cell Reports: Methods, Vol 2, Iss 9, Pp 100288- (2022)
Summary: Large-scale studies of human proteomes have revealed only a moderate correlation between mRNA and protein abundances. It is unclear to what extent this moderate correlation reflects post-transcriptional regulation and to what extent it refle
Externí odkaz:
https://doaj.org/article/9423032250c4410d9db70ddc837c7206
Autor:
Katherine Beck, Atheeshaan Arumuham, Mattia Veronese, Barbara Santangelo, Colm J. McGinnity, Joel Dunn, Robert A. McCutcheon, Stephen J. Kaar, Nisha Singh, Toby Pillinger, Faith Borgan, James Stone, Sameer Jauhar, Teresa Sementa, Federico Turkheimer, Alexander Hammers, Oliver D. Howes
Publikováno v:
Translational Psychiatry, Vol 11, Iss 1, Pp 1-8 (2021)
Abstract N-methyl-D-aspartate receptor (NMDAR) hypofunction is hypothesised to underlie psychosis but this has not been tested early in illness. To address this, we studied 40 volunteers (21 patients with first-episode psychosis and 19 matched health
Externí odkaz:
https://doaj.org/article/01e5daca97374a1c9b30a252f899148c
Autor:
Senri Oyama, Ayumu Hosoi, Masanobu Ibaraki, Colm J. McGinnity, Keisuke Matsubara, Shoichi Watanuki, Hiroshi Watabe, Manabu Tashiro, Miho Shidahara
Publikováno v:
EJNMMI Physics, Vol 7, Iss 1, Pp 1-15 (2020)
Abstract Background Novel partial volume correction (PVC) algorithms have been validated by assuming ideal conditions of image processing; however, in real clinical PET studies, the input datasets include error sources which cause error propagation t
Externí odkaz:
https://doaj.org/article/7399ca07bda7429688904eb13d82d1e7
Autor:
Susan A. Kennedy, Mohamed-Ali Jarboui, Sriganesh Srihari, Cinzia Raso, Kenneth Bryan, Layal Dernayka, Theodosia Charitou, Manuel Bernal-Llinares, Carlos Herrera-Montavez, Aleksandar Krstic, David Matallanas, Max Kotlyar, Igor Jurisica, Jasna Curak, Victoria Wong, Igor Stagljar, Thierry LeBihan, Lisa Imrie, Priyanka Pillai, Miriam A. Lynn, Erik Fasterius, Cristina Al-Khalili Szigyarto, James Breen, Christina Kiel, Luis Serrano, Nora Rauch, Oleksii Rukhlenko, Boris N. Kholodenko, Luis F. Iglesias-Martinez, Colm J. Ryan, Ruth Pilkington, Patrizia Cammareri, Owen Sansom, Steven Shave, Manfred Auer, Nicola Horn, Franziska Klose, Marius Ueffing, Karsten Boldt, David J. Lynn, Walter Kolch
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
Kras is often mutated in colorectal cancer but how this oncogenic mutation alters signalling pathways globally is undetermined. Here, the authors analyse how this mutation affects protein interaction networks and signal flow showing an extensive re
Externí odkaz:
https://doaj.org/article/9d3d9f430d2e481298f1f134583ff8b6