π-HuB: the proteomic navigator of the human body.

Autor: He F; State Key Laboratory of Medical Proteomics, Beijing Proteome Research Center, National Center for Protein Sciences (Beijing), Beijing Institute of Lifeomics, Beijing, China. hefc@bmi.ac.cn.; International Academy of Phronesis Medicine (Guangdong), Guangdong, China. hefc@bmi.ac.cn., Aebersold R; Department of Biology, Institute of Molecular Systems Biology, ETH Zurich, Zurich, Switzerland. aebersold@imsb.biol.ethz.ch., Baker MS; Macquarie Medical School, Macquarie University, Sydney, New South Wales, Australia., Bian X; Institute of Pathology and Southwest Cancer Center, Southwest Hospital, Third Military Medical University (Army Medical University) and Key Laboratory of Tumor Immunopathology, Ministry of Education of China, Chongqing, China., Bo X; Institute of Health Service and Transfusion Medicine, Beijing, China., Chan DW; Department of Pathology and The Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, Baltimore, MD, USA., Chang C; State Key Laboratory of Medical Proteomics, Beijing Proteome Research Center, National Center for Protein Sciences (Beijing), Beijing Institute of Lifeomics, Beijing, China., Chen L; Key Laboratory of Systems Biology, Center for Excellence in Molecular Cell Science, Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences, Shanghai, China., Chen X; Department of Nephrology, First Medical Center of Chinese PLA General Hospital, Nephrology Institute of the Chinese People's Liberation Army, State Key Laboratory of Kidney Diseases, National Clinical Research Center for Kidney Diseases, Beijing Key Laboratory of Kidney Disease Research, Beijing, China., Chen YJ; Institute of Chemistry, Academia Sinica, Taipei, China., Cheng H; National Biomedical Imaging Center, State Key Laboratory of Membrane Biology, Institute of Molecular Medicine, Peking-Tsinghua Center for Life Sciences, College of Future Technology, Peking University, Beijing, China., Collins BC; School of Biological Sciences, Queen's University of Belfast, Belfast, UK., Corrales F; Functional Proteomics Laboratory, Centro Nacional de Biotecnología-CSIC, Madrid, Spain., Cox J; Computational Systems Biochemistry Research Group, Max-Planck Institute of Biochemistry, Martinsried, Germany., E W; AI for Science Institute, Beijing, China.; Center for Machine Learning Research, Peking University, Beijing, China., Van Eyk JE; Advanced Clinical Biosystems Research Institute, Cedars Sinai Medical Center, Los Angeles, CA, USA., Fan J; Department of Liver Surgery and Transplantation, Key Laboratory of Carcinogenesis and Cancer Invasion (Ministry of Education), Liver Cancer Institute, Zhongshan Hospital, Fudan University, Shanghai, China., Faridi P; Centre for Cancer Research, Hudson Institute of Medical Research, Clayton, Victoria, Australia.; Monash Proteomics and Metabolomics Platform, Department of Medicine, School of Clinical Sciences, Monash University, Clayton, Victoria, Australia., Figeys D; School of Pharmaceutical Sciences and Department of Biochemistry, Microbiology and Immunology, Faculty of Medicine, University of Ottawa, Ottawa, Ontario, Canada., Gao GF; The D. H. Chen School of Universal Health, Zhejiang University, Hangzhou, China., Gao W; Pengcheng Laboratory, Shenzhen, China.; School of Electronic Engineering and Computer Science, Peking University, Beijing, China., Gao ZH; Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, British Columbia, Canada., Goda K; Department of Chemistry, University of Tokyo, Tokyo, Japan.; Department of Bioengineering, University of California, Los Angeles, California, USA.; Institute of Technological Sciences, Wuhan University, Wuhan, Hubei, China., Goh WWB; Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore., Gu D; School of Medicine, Southern University of Science and Technology, Shenzhen, China., Guo C; Department of Nutrition, Tianjin Institute of Environmental and Operational Medicine, Tianjin, China., Guo T; School of Medicine, Westlake University, Hangzhou, China.; Westlake Center for Intelligent Proteomics, Westlake Laboratory of Life Sciences and Biomedicine, Hangzhou, China.; Research Center for Industries of the Future, School of Life Sciences, Westlake University, Hangzhou, China., He Y; International Academy of Phronesis Medicine (Guangdong), Guangdong, China., Heck AJR; Biomolecular Mass Spectrometry and Proteomics, Bijvoet Center for Biomolecular Research and Utrecht Institute for Pharmaceutical Sciences, University of Utrecht, Utrecht, the Netherlands.; Netherlands Proteomics Center, Utrecht, the Netherlands., Hermjakob H; European Molecular Biology Laboratory, European Bioinformatics Institute (EMBL-EBI), Cambridge, UK., Hunter T; Molecular and Cell Biology Laboratory, Salk Institute for Biological Studies, La Jolla, CA, USA., Iyer NG; Department of Head & Neck Surgery, Division of Surgery & Surgical Oncology, Division of Medical Sciences, National Cancer Centre Singapore, Singapore, Singapore., Jiang Y; State Key Laboratory of Medical Proteomics, Beijing Proteome Research Center, National Center for Protein Sciences (Beijing), Beijing Institute of Lifeomics, Beijing, China., Jimenez CR; OncoProteomics Laboratory, Department of Medical Oncology, Cancer Center Amsterdam, Amsterdam UMC, Amsterdam, the Netherlands., Joshi L; Advanced Glycoscience Research Cluster, School of Biological and Chemical Sciences, University of Galway, Galway, Ireland., Kelleher NL; Departments of Molecular Biosciences, Departments of Chemistry, Northwestern University, Evanston, IL, USA., Li M; David R. Cheriton School of Computer Science, University of Waterloo, Waterloo, Ontario, Canada.; Central China Institute of Artificial Intelligence, Henan, China., Li Y; State Key Laboratory of Medical Proteomics, Beijing Proteome Research Center, National Center for Protein Sciences (Beijing), Beijing Institute of Lifeomics, Beijing, China., Lin Q; Department of Biological Sciences, Faculty of Science, National University of Singapore, Singapore, Singapore., Liu CH; CAS Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences, Beijing, China., Liu F; Department of Structural Biology, Leibniz-Forschungsinstitut für MolekularePharmakologie (FMP), Berlin, Germany., Liu GH; State Key Laboratory of Membrane Biology, Key Laboratory of Organ Regeneration and Reconstruction, Institute of Zoology, Chinese Academy of Sciences, Beijing, China., Liu Y; Cancer Biology Institute, Yale University School of Medicine, West Haven, CT, USA., Liu Z; State Key Laboratory of Molecular Oncology, National Cancer Center, National Clinical Research Center for Cancer, Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China., Low TY; UKM Medical Molecular Biology Institute (UMBI), Universiti Kebangsaan Malaysia, Kuala Lumpur, Malaysia., Lu B; Department of Critical Care Medicine and Hematology, The Third Xiangya Hospital, Central South University; Department of Hematology and Critical Care Medicine, The Third Xiangya Hospital, Central South University, Changsha, China., Mann M; Proteomics and Signal Transduction, Max Planck Institute of Biochemistry, Martinsried, Germany., Meng A; School of Life Sciences, Tsinghua University, Tsinghua-Peking Center for Life Sciences, Beijing, China., Moritz RL; Institute for Systems Biology, Seattle, WA, USA., Nice E; Clinical Biomarker Discovery and Validation, Monash University, Clayton, Victoria, Australia., Ning G; Department of Endocrine and Metabolic Diseases, Shanghai Institute of Endocrine and Metabolic Diseases, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.; Shanghai National Clinical Research Center for Metabolic Diseases, Key Laboratory for Endocrine and Metabolic Diseases of the National Health Commission of the PR China, Shanghai, China.; Shanghai Key Laboratory for Endocrine Tumor, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China., Omenn GS; Center for Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI, USA., Overall CM; Department of Oral Biological and Medical Sciences, University of British Columbia, Vancouver, British Columbia, Canada.; Yonsei Frontier Lab, Yonsei University, Seoul, Republic of Korea., Palmisano G; Glycoproteomics Laboratory, Department of Parasitology, University of São Paulo, Sao Paulo, Brazil., Peng Y; Institute of Zoology, Chinese Academy of Sciences, Beijing, China.; Beijing Institute for Stem Cell and Regenerative Medicine, Beijing, China.; University of the Chinese Academy of Sciences, Beijing, China., Pineau C; Institut de Recherche en Santé Environnement et Travail, Univ. Rennes, Inserm, EHESP, Irset, Rennes, France., Poon TCW; Pilot Laboratory, MOE Frontier Science Centre for Precision Oncology, Centre for Precision Medicine Research and Training, Institute of Translational Medicine, Faculty of Health Sciences, University of Macau, Macau, China., Purcell AW; Infection and Immunity Program and Department of Biochemistry and Molecular Biology, Biomedicine Discovery Institute, Monash University, Clayton, Victoria, Australia., Qiao J; State Key Laboratory of Female Fertility Promotion, Center for Reproductive Medicine, Department of Obstetrics and Gynecology, Peking University Third Hospital, Beijing, China., Reddel RR; ProCan®, Children's Medical Research Institute, Faculty of Medicine and Health, The University of Sydney, Westmead, New South Wales, Australia., Robinson PJ; ProCan®, Children's Medical Research Institute, Faculty of Medicine and Health, The University of Sydney, Westmead, New South Wales, Australia., Roncada P; Department of Health Sciences, University Magna Græcia of Catanzaro, Catanzaro, Italy., Sander C; Department of Systems Biology, Harvard Medical School, Boston, MA, USA.; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Sha J; State Key Laboratory of Reproductive Medicine, Nanjing Medical University, Nanjing, China., Song E; Guangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation, Medical Research Center, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, China.; Breast Tumor Center, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, China., Srivastava S; Indian Institute of Technology Bombay, Mumbai, India., Sun A; State Key Laboratory of Medical Proteomics, Beijing Proteome Research Center, National Center for Protein Sciences (Beijing), Beijing Institute of Lifeomics, Beijing, China., Sze SK; Department of Health Sciences, Faculty of Applied Health Sciences, Brock University, St. Catharines, Ontario, Canada., Tang C; Center for Quantitative Biology, Peking-Tsinghua Center for Life Sciences, Peking University, Beijing, China., Tang L; State Key Laboratory of Medical Proteomics, Beijing Proteome Research Center, National Center for Protein Sciences (Beijing), Beijing Institute of Lifeomics, Beijing, China., Tian R; Department of Chemistry, Southern University of Science and Technology, Shenzhen, China., Vizcaíno JA; European Molecular Biology Laboratory, European Bioinformatics Institute (EMBL-EBI), Cambridge, UK., Wang C; State Key Laboratory of Medical Proteomics, Beijing Proteome Research Center, National Center for Protein Sciences (Beijing), Beijing Institute of Lifeomics, Beijing, China., Wang C; State Key Laboratory of Respiratory Health and Multimorbidity, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences, School of Basic Medicine, Peking Union Medical College, Beijing, China.; Department of Pulmonary and Critical Care Medicine, Center of Respiratory Medicine, National Clinical Research Center for Respiratory Diseases, China-Japan Friendship Hospital, Beijing, China., Wang X; State Key Laboratory of Medical Proteomics, Beijing Proteome Research Center, National Center for Protein Sciences (Beijing), Beijing Institute of Lifeomics, Beijing, China., Wang X; Department of Nutrition, Tianjin Institute of Environmental and Operational Medicine, Tianjin, China., Wang Y; State Key Laboratory of Medical Proteomics, Beijing Proteome Research Center, National Center for Protein Sciences (Beijing), Beijing Institute of Lifeomics, Beijing, China., Weiss T; Department of Neurology, Clinical Neuroscience Center, University Hospital Zurich and University of Zurich, Zurich, Switzerland., Wilhelm M; Technical University of Munich, Freising, Germany., Winkler R; Advanced Genomics Unit, Center for Research and Advanced Studies, Irapuato, Mexico., Wollscheid B; Institute of Translational Medicine, Department of Health Sciences and Technology, ETH Zurich, Zurich, Switzerland., Wong L; Department of Computer Science, National University of Singapore, Singapore, Singapore.; Department of Pathology, National University of Singapore, Singapore, Singapore., Xie L; State Key Laboratory of Medical Proteomics, Beijing Proteome Research Center, National Center for Protein Sciences (Beijing), Beijing Institute of Lifeomics, Beijing, China., Xie W; School of Life Sciences, Tsinghua University, Tsinghua-Peking Center for Life Sciences, Beijing, China., Xu T; Guangzhou National Laboratory, Guangzhou, China.; School of Biomedical Engineering, Guangzhou Medical University, Guangzhou, China., Xu T; International Academy of Phronesis Medicine (Guangdong), Guangdong, China., Yan L; State Key Laboratory of Female Fertility Promotion, Center for Reproductive Medicine, Department of Obstetrics and Gynecology, Peking University Third Hospital, Beijing, China., Yang J; Guangzhou National Laboratory, Guangzhou, China., Yang X; State Key Laboratory of Medical Proteomics, Beijing Proteome Research Center, National Center for Protein Sciences (Beijing), Beijing Institute of Lifeomics, Beijing, China., Yates J; The Scripps Research Institute, La Jolla, CA, USA., Yun T; China Science and Technology Exchange Center, Beijing, China. yuntaotc123@qq.com., Zhai Q; CAS Key Laboratory of Nutrition, Metabolism and Food Safety, Shanghai Institute of Nutrition and Health, University of Chinese Academy of Sciences, Chinese Academy of Sciences, Shanghai, China., Zhang B; Lester and Sue Smith Breast Center, Baylor College of Medicine, Houston, TX, USA.; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX, USA., Zhang H; Department of Pathology, Johns Hopkins School of Medicine, Baltimore, MD, USA., Zhang L; State Key Laboratory of Medical Proteomics, National Chromatography R. & A. Center, CAS Key Laboratory of Separation Science for Analytical Chemistry, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian, China., Zhang L; State Key Laboratory of Medical Proteomics, Beijing Proteome Research Center, National Center for Protein Sciences (Beijing), Beijing Institute of Lifeomics, Beijing, China., Zhang P; School of Mathematical Sciences, Peking University, Beijing, China.; Wuhan University, Wuhan, China., Zhang Y; State Key Laboratory of Medical Proteomics, National Chromatography R. & A. Center, CAS Key Laboratory of Separation Science for Analytical Chemistry, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian, China., Zheng YZ; International Academy of Phronesis Medicine (Guangdong), Guangdong, China.; Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, British Columbia, Canada., Zhong Q; ProCan®, Children's Medical Research Institute, Faculty of Medicine and Health, The University of Sydney, Westmead, New South Wales, Australia., Zhu Y; State Key Laboratory of Medical Proteomics, Beijing Proteome Research Center, National Center for Protein Sciences (Beijing), Beijing Institute of Lifeomics, Beijing, China.

Publikováno v: Nature [Nature] 2024 Dec; Vol. 636 (8042), pp. 322-331. Date of Electronic Publication: 2024 Dec 11.

Proteomic Characterisation of Heart Failure Reveals a Unique Molecular Phenotype for Hypertrophic Cardiomyopathy.

Autor: Tonry C; Wellcome-Wolfson Institute for Experimental Medicine, Queen's University Belfast, Belfast BT9 7BL, UK., Linden K; Wellcome-Wolfson Institute for Experimental Medicine, Queen's University Belfast, Belfast BT9 7BL, UK., Collier P; Department of Cardiovascular Medicine, Cleveland Clinic, OH 44195, USA., Ledwidge M; STOP-HF Unit, Department of Cardiology, St. Vincent's University Hospital Healthcare Group, D04 T6F4 Dublin, Ireland.; UCD Conway Institute of Biomolecular and Biomedical Research, School of Medicine, University College Dublin, D04 V1W8 Dublin, Ireland., McDonald K; STOP-HF Unit, Department of Cardiology, St. Vincent's University Hospital Healthcare Group, D04 T6F4 Dublin, Ireland.; UCD Conway Institute of Biomolecular and Biomedical Research, School of Medicine, University College Dublin, D04 V1W8 Dublin, Ireland., Collins BC; School of Biological Sciences, Queen's University Belfast, Belfast BT9 5DL, UK., Watson CJ; Wellcome-Wolfson Institute for Experimental Medicine, Queen's University Belfast, Belfast BT9 7BL, UK.; STOP-HF Unit, Department of Cardiology, St. Vincent's University Hospital Healthcare Group, D04 T6F4 Dublin, Ireland.; UCD Conway Institute of Biomolecular and Biomedical Research, School of Medicine, University College Dublin, D04 V1W8 Dublin, Ireland.

Publikováno v: Biomedicines [Biomedicines] 2024 Aug 01; Vol. 12 (8). Date of Electronic Publication: 2024 Aug 01.

Ablation of skeletal muscle estrogen receptor alpha impairs contractility in male mice.

Autor: Sullivan BP; Division of Physical Therapy and Rehabilitation Science, Department of Family Medicine and Community Health, University of Minnesota, Minneapolis, Minnesota, United States., Collins BC; Division of Physical Therapy and Rehabilitation Science, Department of Family Medicine and Community Health, University of Minnesota, Minneapolis, Minnesota, United States., McMillin SL; Division of Physical Therapy and Rehabilitation Science, Department of Family Medicine and Community Health, University of Minnesota, Minneapolis, Minnesota, United States., Toussaint E; Division of Physical Therapy and Rehabilitation Science, Department of Family Medicine and Community Health, University of Minnesota, Minneapolis, Minnesota, United States., Stein CZ; Division of Physical Therapy and Rehabilitation Science, Department of Family Medicine and Community Health, University of Minnesota, Minneapolis, Minnesota, United States., Spangenburg EE; Department of Physiology, Brody School of Medicine, East Carolina Diabetes and Obesity Institute, East Carolina University, Greenville, North Carolina, United States., Lowe DA; Division of Physical Therapy and Rehabilitation Science, Department of Family Medicine and Community Health, University of Minnesota, Minneapolis, Minnesota, United States.

Publikováno v: Journal of applied physiology (Bethesda, Md. : 1985) [J Appl Physiol (1985)] 2024 Apr 01; Vol. 136 (4), pp. 764-773. Date of Electronic Publication: 2024 Feb 08.

Identification of small-molecule protein-protein interaction inhibitors for NKG2D.

Autor: Thompson AA; Therapeutics Discovery, Janssen Research & Development, San Diego, CA 92121., Harbut MB; Therapeutics Discovery, Janssen Research & Development, Lower Gwynedd Township, PA 19002., Kung PP; Therapeutics Discovery, Janssen Research & Development, San Diego, CA 92121., Karpowich NK; Therapeutics Discovery, Janssen Research & Development, Lower Gwynedd Township, PA 19002., Branson JD; Therapeutics Discovery, Janssen Research & Development, Lower Gwynedd Township, PA 19002., Grant JC; Therapeutics Discovery, Janssen Research & Development, San Diego, CA 92121., Hagan D; Therapeutics Discovery, Janssen Research & Development, Lower Gwynedd Township, PA 19002., Pascual HA; Therapeutics Discovery, Janssen Research & Development, San Diego, CA 92121., Bai G; Therapeutics Discovery, Janssen Research & Development, San Diego, CA 92121., Zavareh RB; Therapeutics Discovery, Janssen Research & Development, San Diego, CA 92121., Coate HR; Therapeutics Discovery, Janssen Research & Development, San Diego, CA 92121., Collins BC; Therapeutics Discovery, Janssen Research & Development, San Diego, CA 92121., Côte M; Therapeutics Discovery, Janssen Research & Development, San Diego, CA 92121., Gelin CF; Therapeutics Discovery, Janssen Research & Development, San Diego, CA 92121., Damm-Ganamet KL; Therapeutics Discovery, Janssen Research & Development, San Diego, CA 92121., Gholami H; Therapeutics Discovery, Janssen Research & Development, San Diego, CA 92121., Huff AR; Therapeutics Discovery, Janssen Research & Development, Lower Gwynedd Township, PA 19002., Limon L; Therapeutics Discovery, Janssen Research & Development, San Diego, CA 92121., Lumb KJ; Therapeutics Discovery, Janssen Research & Development, Lower Gwynedd Township, PA 19002., Mak PA; Therapeutics Discovery, Janssen Research & Development, San Diego, CA 92121., Nakafuku KM; Therapeutics Discovery, Janssen Research & Development, San Diego, CA 92121., Price EV; Therapeutics Discovery, Janssen Research & Development, Lower Gwynedd Township, PA 19002., Shih AY; Therapeutics Discovery, Janssen Research & Development, San Diego, CA 92121., Tootoonchi M; Discovery Immunology, Janssen Research & Development, San Diego, CA 92121., Vellore NA; Therapeutics Discovery, Janssen Research & Development, San Diego, CA 92121., Wang J; Therapeutics Discovery, Janssen Research & Development, San Diego, CA 92121., Wei N; Therapeutics Discovery, Janssen Research & Development, San Diego, CA 92121., Ziff J; Therapeutics Discovery, Janssen Research & Development, San Diego, CA 92121., Berger SB; Discovery Immunology, Janssen Research & Development, Lower Gwynedd Township, PA 19002., Edwards JP; Therapeutics Discovery, Janssen Research & Development, San Diego, CA 92121., Gardet A; Discovery Immunology, Janssen Research & Development, San Diego, CA 92121., Sun S; Discovery Immunology, Janssen Research & Development, San Diego, CA 92121., Towne JE; Discovery Immunology, Janssen Research & Development, San Diego, CA 92121., Venable JD; Therapeutics Discovery, Janssen Research & Development, San Diego, CA 92121., Shi Z; Therapeutics Discovery, Janssen Research & Development, Lower Gwynedd Township, PA 19002., Venkatesan H; Therapeutics Discovery, Janssen Research & Development, San Diego, CA 92121., Rives ML; Therapeutics Discovery, Janssen Research & Development, San Diego, CA 92121., Sharma S; Therapeutics Discovery, Janssen Research & Development, Lower Gwynedd Township, PA 19002., Shireman BT; Therapeutics Discovery, Janssen Research & Development, San Diego, CA 92121., Allen SJ; Therapeutics Discovery, Janssen Research & Development, Lower Gwynedd Township, PA 19002.

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2023 May 02; Vol. 120 (18), pp. e2216342120. Date of Electronic Publication: 2023 Apr 25.

Fibroblast-derived Hgf controls recruitment and expansion of muscle during morphogenesis of the mammalian diaphragm.

Autor: Sefton EM; Department of Human Genetics, University of Utah, Salt Lake City, United States., Gallardo M; Department of Human Genetics, University of Utah, Salt Lake City, United States., Tobin CE; Department of Human Genetics, University of Utah, Salt Lake City, United States., Collins BC; Department of Human Genetics, University of Utah, Salt Lake City, United States., Colasanto MP; Department of Human Genetics, University of Utah, Salt Lake City, United States., Merrell AJ; Ambys Medicines, South San Francisco, United States., Kardon G; Department of Human Genetics, University of Utah, Salt Lake City, United States.

Publikováno v: ELife [Elife] 2022 Sep 26; Vol. 11. Date of Electronic Publication: 2022 Sep 26.