Zobrazeno 1 - 10
of 120
pro vyhledávání: '"Collin de l'Hortet A"'
Autor:
Florentino, Rodrigo M., Morita, Kazutoyo, Haep, Nils, Motomura, Takashi, Diaz-Aragon, Ricardo, Faccioli, Lanuza A.P., Collin de l’Hortet, Alexandra, Cetin, Zeliha, Frau, Carla, Vernetti, Lawrence, Amler, Anna-Klara, Thomas, Alexander, Lam, Tobias, Kloke, Lutz, Takeishi, Kazuki, Taylor, D. Lansing, Fox, Ira J., Soto-Gutierrez, Alejandro
Publikováno v:
In iScience 22 December 2022 25(12)
Autor:
Rodrigo M. Florentino, Kazutoyo Morita, Nils Haep, Takashi Motomura, Ricardo Diaz-Aragon, Lanuza A.P. Faccioli, Alexandra Collin de l’Hortet, Zeliha Cetin, Carla Frau, Lawrence Vernetti, Anna-Klara Amler, Alexander Thomas, Tobias Lam, Lutz Kloke, Kazuki Takeishi, D. Lansing Taylor, Ira J. Fox, Alejandro Soto-Gutierrez
Publikováno v:
iScience, Vol 25, Iss 12, Pp 105503- (2022)
Summary: Advances in cellular engineering, as well as gene, and cell therapy, may be used to produce human tissues with programmable genetically enhanced functions designed to model and/or treat specific diseases. Fabrication of synthetic human liver
Externí odkaz:
https://doaj.org/article/456852f3c07c4362a0ae4b0b01b19d89
Autor:
Rodrigo M. Florentino, Nicolas A. Fraunhoffer, Kazutoyo Morita, Kazuki Takeishi, Alina Ostrowska, Abhinav Achreja, Olamide Animasahun, Nils Haep, Shohrat Arazov, Nandini Agarwal, Alexandra Collin de l'Hortet, Jorge Guzman‐Lepe, Edgar N. Tafaleng, Amitava Mukherjee, Kris Troy, Swati Banerjee, Shirish Paranjpe, George K. Michalopoulos, Aaron Bell, Deepak Nagrath, Sarah J. Hainer, Ira J. Fox, Alejandro Soto‐Gutierrez
Publikováno v:
Hepatology Communications, Vol 4, Iss 6, Pp 859-875 (2020)
Hepatocyte nuclear factor 4 alpha (HNF4α) is a transcription factor that plays a critical role in hepatocyte function, and HNF4α‐based reprogramming corrects terminal liver failure in rats with chronic liver disease. In the livers of patients wit
Externí odkaz:
https://doaj.org/article/a366b3ff63454cfe85adee4824c052ae
Autor:
Collin de l’Hortet, Alexandra, Takeishi, Kazuki, Guzman-Lepe, Jorge, Morita, Kazutoyo, Achreja, Abhinav, Popovic, Branimir, Wang, Yang, Handa, Kan, Mittal, Anjali, Meurs, Noah, Zhu, Ziwen, Weinberg, Frank, Salomon, Michael, Fox, Ira J., Deng, Chu-Xia, Nagrath, Deepak, Soto-Gutierrez, Alejandro
Publikováno v:
In Cell Metabolism 6 August 2019 30(2):385-401
Publikováno v:
In The American Journal of Pathology March 2019 189(3):502-512
Publikováno v:
In The American Journal of Pathology June 2018 188(6):1316-1327
Autor:
Kazuki Takeishi, Alexandra Collin de l’Hortet, Yang Wang, Kan Handa, Jorge Guzman-Lepe, Kentaro Matsubara, Kazutoyo Morita, Sae Jang, Nils Haep, Rodrigo M. Florentino, Fangchao Yuan, Ken Fukumitsu, Kimimasa Tobita, Wendell Sun, Jonathan Franks, Evan R. Delgado, Erik M. Shapiro, Nicolas A. Fraunhoffer, Andrew W. Duncan, Hiroshi Yagi, Tomoji Mashimo, Ira J. Fox, Alejandro Soto-Gutierrez
Publikováno v:
Cell Reports, Vol 31, Iss 9, Pp - (2020)
Summary: The availability of an autologous transplantable auxiliary liver would dramatically affect the treatment of liver disease. Assembly and function in vivo of a bioengineered human liver derived from induced pluripotent stem cells (iPSCs) has n
Externí odkaz:
https://doaj.org/article/2669d2ed58534d89a4a0eccc2bf0473f
Autor:
Collin de l’Hortet, A., Takeishi, K., Guzman-Lepe, J., Handa, K., Matsubara, K., Fukumitsu, K., Dorko, K., Presnell, S.C., Yagi, H., Soto-Gutierrez, A. *
Publikováno v:
In American Journal of Transplantation June 2016 16(6):1688-1696
Autor:
Takamasa Tobita, Jorge Guzman-Lepe, Kazuki Takeishi, Toshimasa Nakao, Yang Wang, Fanying Meng, Chu-Xia Deng, Alexandra Collin de l'Hortet, Alejandro Soto-Gutierrez
Publikováno v:
PLoS ONE, Vol 11, Iss 2, p e0149344 (2016)
There are unprecedented epidemics of obesity, such as type II diabetes and non-alcoholic fatty liver diseases (NAFLD) in developed countries. A concerning percentage of American children are being affected by obesity and NAFLD. Studies have suggested
Externí odkaz:
https://doaj.org/article/c62d8a4077434fafb542fe025ce4aff0
Publikováno v:
Journal of Nuclear Engineering and Radiation Science. 8
The present work aims at testing the computational fluid dynamics capabilities to simulate erosion of materials which interact with a corium mass. The main foreseen application is the design of external/internal core catchers or in-vessel retentions