Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Collin Xia"'
Autor:
Collin Xia
Publikováno v:
Caribbean Quilt, Vol 6, Iss 1 (2022)
Beginning in the 1780s, British Caribbean plantocracies faced the looming threat of slave trade abolition which would end the flow of enslaved labour fundamental to colonial plantation economies. Enslaved women’s function as the source of blackness
Externí odkaz:
https://doaj.org/article/594068f365244c1ab200e4ec023a5053
Autor:
Lawrence J. Thomas, Laura A. Vitale, Michael Murphy, Collin Xia, Zeyu Peng, Asma Ejas, Montu Patel, James Boyer, April R. Baronas, Thomas O'Neill, Jenifer Widger, Laura Mills-Chen, Andrea Crocker, Mark Ma, Mingjiu Chen, Hugh M. Davis, Russ A. Hammond, Cherie Taglienti, Michael Yellin, Joel Goldstein, Diego Alvarado, Henry C. Marsh, Tibor Keler
Publikováno v:
Cancer Research. 83:2963-2963
Both PD-1 and ILT4 (LILRB2, CD85d) have well established immunosuppressive effects that enable tumors to evade anti-tumor immunity. Tumor expression of PD-L1 and ILT4 has been associated with poor clinical outcomes in several cancer types. Recently,
Autor:
Linda Crew, Zeyu Peng, Thomas O'Neill, James L. Boyer, Mark Z. Ma, Michael T. Murphy, Lawrence J. Thomas, Jeff Weidlick, Colleen Patterson, Russell A. Hammond, Diego Alvarado, Anna Wasiuk, April R. Baronas, Joel Goldstein, Laura Mills-Chen, Tibor Keler, Andrea Crocker, Jay S. Lillquist, Jenifer Widger, Laura Vitale, Ed Natoli, Collin Xia, Henry C. Marsh, Hugh Davis
Publikováno v:
Journal for ImmunoTherapy of Cancer. 9:A833-A833
BackgroundActivation of the ITIM-bearing ILT4/LILRB2 receptor by its cognate ligands (HLA-G and HLA Class I) has been postulated as a resistance mechanism for checkpoint blockade of PD-1 and CTLA-4. Dual inhibition of receptors that suppress myeloid