Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Collin Polucha"'
Autor:
Rajeev J. Kant, Kiera D. Dwyer, Jang-Hoon Lee, Collin Polucha, Momoka Kobayashi, Stephen Pyon, Arvin H. Soepriatna, Jonghwan Lee, Kareen L. K. Coulombe
Publikováno v:
Cells, Vol 12, Iss 13, p 1698 (2023)
Heart regeneration after myocardial infarction (MI) using human stem cell-derived cardiomyocytes (CMs) is rapidly accelerating with large animal and human clinical trials. However, vascularization methods to support the engraftment, survival, and dev
Externí odkaz:
https://doaj.org/article/05c0d69b5ab745648949c984eb650893
Autor:
Nora Bloise, Isobel Rountree, Collin Polucha, Giulia Montagna, Livia Visai, Kareen L. K. Coulombe, Fabiola Munarin
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 8 (2020)
Coronary artery disease is a severe ischemic condition characterized by the reduction of blood flow in the arteries of the heart that results in the dysfunction and death of cardiac tissue. Despite research over several decades on how to reduce long-
Externí odkaz:
https://doaj.org/article/c258e407b9f24328b8ac3944f5d29c66
Publikováno v:
Journal of Innovative Optical Health Sciences, Vol 13, Iss 1, Pp 2030002-1-2030002-16 (2020)
Optical coherence tomography angiography (OCTA) has emerged as an advanced in vivo imaging modality, which is widely used for the clinic ophthalmology and neuroscience research in the rodent brain cortex among others. Based on the high numerical aper
Externí odkaz:
https://doaj.org/article/3bcb60fd87194866a69d5bdc52d87a0a
Autor:
Coulombe, Rajeev J. Kant, Kiera D. Dwyer, Jang-Hoon Lee, Collin Polucha, Momoka Kobayashi, Stephen Pyon, Arvin H. Soepriatna, Jonghwan Lee, Kareen L. K.
Publikováno v:
Cells; Volume 12; Issue 13; Pages: 1698
Heart regeneration after myocardial infarction (MI) using human stem cell-derived cardiomyocytes (CMs) is rapidly accelerating with large animal and human clinical trials. However, vascularization methods to support the engraftment, survival, and dev
Publikováno v:
Tissue Eng Part A
With this work, we design alginate-based hydrogels for therapeutically directing revascularization and repair processes in vivo. We immobilize pleiotrophin (PTN) in injectable hydrogel formulations as the target factor to stimulate proangiogenic resp
Publikováno v:
Circulation Research. 131
Over 800,000 myocardial infarctions (MI) occur annually in the United States alone, 25% of which represent a repeat occurrence further indicating chronic ischemia in the myocardium. Cardiovascular regeneration is largely dependent on the stimulation
Publikováno v:
Circulation Research. 131
Globally, >6 million patients with heart failure (HF) have reduced ejection fraction due to prior myocardial infarction (MI). In the U.S., 50,000 become refractory to treatment each year and novel therapies are urgently needed to treat systolic dysfu
Autor:
Alicia Minor, Stephanie Roser, Keyana Zahiri, Elena Song, Momoka Kobayashi, Collin Polucha, Kareen L Coulombe
Publikováno v:
Circulation Research. 131
The limited regenerative capacity of the adult human heart presents a critical need to stabilize and support injured heart muscle to mitigate the progression of heart failure. The effectiveness of remuscularization therapies using human induced pluri
Autor:
Nora Bloise, Isobel Rountree, Collin Polucha, Giulia Montagna, Livia Visai, Kareen L. K. Coulombe, Fabiola Munarin
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 8 (2020)
Frontiers in Bioengineering and Biotechnology
Frontiers in Bioengineering and Biotechnology
Coronary artery disease is a severe ischemic condition characterized by the reduction of blood flow in the arteries of the heart that results in the dysfunction and death of cardiac tissue. Despite research over several decades on how to reduce long-
Publikováno v:
Journal of Innovative Optical Health Sciences, Vol 13, Iss 1, Pp 2030002-1-2030002-16 (2020)
Optical coherence tomography angiography (OCTA) has emerged as an advanced in vivo imaging modality, which is widely used for the clinic ophthalmology and neuroscience research in the rodent brain cortex among others. Based on the high numerical aper