Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Collin M. Hagen"'
Autor:
David B. Rozema, So C. Wong, Vladimir S. Trubetskoy, Almeida Lauren J, Jonathan D. Benson, Julia Hegge, Darren H. Wakefield, Holly Hamilton, Jeffrey C. Carlson, Jon A. Wolff, Eric A. Kitas, David L. Lewis, Qili Chu, Jason Klein, Anthony Nicholas, Collin M. Hagen, Andrei V. Blokhin
Publikováno v:
Journal of Controlled Release. 209:57-66
The safe and efficacious delivery of membrane impermeable therapeutics requires cytoplasmic access without the toxicity of nonspecific cytoplasmic membrane lysis. We have developed a mechanism for control of cytoplasmic release which utilizes endogen
Autor:
Gary Christensen, Aaron Andersen, Collin M. Hagen, Holly Hamilton, Julia Hegge, Zhen Li, Qili Chu, Tracie Milarch, Tao Pei, Christine Chapman, Steven B. Kanner, Crystal Klas, Stacey Melquist, Megan Walters, Casi Schienebeck, Zach Trilling, Jeff Casper
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 37
Introduction: Current anticoagulants effectively prevent thromboembolic (TBE) events, but unmet medical need remains due to elevated risk of major bleeding events, particularly where Factor Xa inhibitors are contraindicated. Factor XII (F12) zymogen
Autor:
Thomas R. Ward, Thomas Bürgi, Georg Süss-Fink, Gaël Labat, Richard G. Finke, Antonia Neels, Collin M. Hagen, Ludovic Vieille-Petit, Helen Stœckli-Evans, Bruno Therrien, Lydia Karmazin-Brelot
Publikováno v:
Organometallics, Vol. 24, No 25 (2005) pp. 6104-6119
To bring evidence for or against the hypothesis of catalytic hydrogenation by intact trinuclear arene ruthenium clusters containing an oxo cap, cationic Ru3O clusters with three different arene ligands (intrinsically chiral tetrahedra) have been synt
Autor:
Georg Süss-Fink, Gábor Laurenczy, Collin M. Hagen, Richard G. Finke, Ludovic Vieille-Petit, Florence Geneste, Claude Moinet, Mathieu J.-L. Tschan
Publikováno v:
Polyhedron. 24:1961-1967
The synthesis of the trinuclear cluster cation [H3RU3(C6H6)(C6Me6)(2)(O)](+) (1) has been considerably improved by changes in the NaBH4 addition step and by introducing chromatographic methods; in addition, the redox and ligand exchange properties of
Publikováno v:
Organometallics. 24:1819-1831
The question is addressed of whether the triruthenium cluster cation [Ru-3(mu(2)-H)(3)(eta(6)C(6)H(6))(eta(6)-C6Me6)(2)(mu(3)-O)](+), 1, is a supramolecular, outer-sphere benzene hydrogenation catalyst or is 1 a precatalyst to well-known Ru(0)(n) cat
Publikováno v:
Journal of the American Chemical Society. 127:4423-4432
Addressed herein is the 20+ year-old question of whether the true benzene and cyclohexene hydrogenation catalysts derived from the organometallic precursor [Rh(eta5-C5Me5)Cl2]2, 1, are homogeneous or heterogeneous. The methodology employed is that de
Autor:
Vladimir S. Trubetskoy, Holly Hamilton, David L. Lewis, Collin M. Hagen, Alan McLachlan, Christine I. Wooddell, Anthony L. Perillo-Nicholas, Jacob B. Griffin, Qili Chu, David B. Rozema
Publikováno v:
Gastroenterology. 144:S-973
Chronic hepatitis B virus (HBV) infection is a major disease for which there remains an unmet medical need. Current therapies for chronic hepatitis B include reverse transcriptase inhibitors and interferon. These therapies either require life-long ad