Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Collin Laaker"'
Publikováno v:
IBRO Neuroscience Reports, Vol 15, Iss , Pp S279-S280 (2023)
Externí odkaz:
https://doaj.org/article/0f1048f019234eb09fb7400e307e1690
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
In recent decades there has been a large focus on understanding the mechanisms of peripheral immune cell infiltration into the central nervous system (CNS) in neuroinflammatory diseases. This intense research led to several immunomodulatory therapies
Externí odkaz:
https://doaj.org/article/4c6be1d8a65b48b999ee550a499d3c33
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 15 (2021)
The central nervous system (CNS) undergoes immunosurveillance despite the lack of conventional antigen presenting cells and lymphatic vessels in the CNS parenchyma. Additionally, the CNS is bathed in a cerebrospinal fluid (CSF). CSF is continuously p
Externí odkaz:
https://doaj.org/article/857980c654af458f9e4e5ee24dec8273
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 17, p 9486 (2021)
Stroke disrupts the homeostatic balance within the brain and is associated with a significant accumulation of necrotic cellular debris, fluid, and peripheral immune cells in the central nervous system (CNS). Additionally, cells, antigens, and other f
Externí odkaz:
https://doaj.org/article/17f84f8b93344605b758580947bdaf4a
Autor:
Zsuzsanna Fabry, Collin Laaker
Publikováno v:
Trends in Immunology. 42:940-942
A new study by Da Mesquita et al. reports on how meningeal lymphatic modulation may influence amyloid-beta immunotherapy and microglial function in mouse models of Alzheimer's disease (AD). This research has broad implications for unraveling the role
Publikováno v:
Current Protocols. 1
Autor:
Dinesh C. Joshi, Krisztian Kovacs, Collin Laaker, Thanthrige Thiunuwan Priyathilaka, Shing Yan Chiu, TaeHee Kim, Peter Cismaru, Julie A. Kijak, Lee Kissel, Raghu Vemuganti, Matyas Sandor, Martin Hsu, Anders Lindstedt, Zsuzsanna Fabry, Aditya Rayasam
Background: Ischemic stroke is a leading cause of mortality worldwide, largely due to the inflammatory response to brain ischemia during post-stroke reperfusion. Despite ongoing intensive research, there have not been any clinically approved drugs ta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::709cb24ba18707a6d07bb2b2b47ab201
https://doi.org/10.21203/rs.3.rs-1032310/v1
https://doi.org/10.21203/rs.3.rs-1032310/v1
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 9486, p 9486 (2021)
International Journal of Molecular Sciences
International Journal of Molecular Sciences
Stroke disrupts the homeostatic balance within the brain and is associated with a significant accumulation of necrotic cellular debris, fluid, and peripheral immune cells in the central nervous system (CNS). Additionally, cells, antigens, and other f
Autor:
Melinda Herbáth, Zsuzsanna Fabry, Andy Madrid, Martin Hsu, Yun Hwa Choi, Collin Laaker, Matyas Sandor
Publikováno v:
Nat Immunol
Meningeal lymphatic vessels residing in the dural layer above the sinuses of the brain, meninges at the base of the brain, and near the cribriform plate have all been shown to drain fluid, cells, and antigens. We have previously reported that meninge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab753bac549a406bfcb6e8197b315db4
https://doi.org/10.21203/rs.3.rs-543816/v1
https://doi.org/10.21203/rs.3.rs-543816/v1
Autor:
Zsuzsanna Fabry, Martin Hsu, Andy Madrid, Yun Hwa Choi, Matyas Sandor, Melinda Herbáth, Collin Laaker
Meningeal lymphatic vessels residing in the dural layer surrounding the dorsal regions of the brain, basal regions, and near the cribriform plate have all been implicated in the management of neuroinflammation and edema. Interestingly, only the lymph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9b947467733c509c1685b1358899c071
https://doi.org/10.1101/2020.10.08.331801
https://doi.org/10.1101/2020.10.08.331801