Výsledky vyhledávání - "Collin J. Anderson"

Akademický článek

Neural selectivity, efficiency, and dose equivalence in deep brain stimulation through pulse width tuning and segmented electrodes

Autor: Collin J. Anderson, Daria Nesterovich Anderson, Stefan M. Pulst, Christopher R. Butson, Alan D. Dorval

Publikováno v: Brain Stimulation, Vol 13, Iss 4, Pp 1040-1050 (2020)

Background: Achieving deep brain stimulation (DBS) dose equivalence is challenging, especially with pulse width tuning and directional contacts. Further, the precise effects of pulse width tuning are unknown, and recent reports of the effects of puls

Externí odkaz: https://doaj.org/article/6d3d0cf6bca74f63be417cad6521f43e

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Targeting Staufen 1 with antisense oligonucleotides for treating ALS and SCA2

Autor: Daniel R. Scoles, Sharan Paul, Warunee Dansithong, Karla P. Figueroa, Mandi Gandelman, Feliks Royzen, Collin J. Anderson, Stefan M. Pulst

Staufen1 (STAU1) is a multifunctional RNA binding protein that controls mRNA degradation and subcellular localization. STAU1 interacts with the ATXN2 protein, that is polyglutamine expanded in spinocerebellar ataxia type 2 (SCA2). We previously showe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9569bf3f080e1c58dee80a1d9c9f40af
https://doi.org/10.1101/2022.11.16.516816

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Slc9a6 mutation causes Purkinje cell loss and ataxia in the shaker rat

Autor: Karla P Figueroa, Collin J Anderson, Sharan Paul, Warunee Dansithong, Mandi Gandelman, Daniel R Scoles, Stefan M Pulst

BackgroundThe shaker rat carries a naturally occurring mutation leading to progressive ataxia characterized by Purkinje cell (PC) loss. We previously reported on fine-mapping the shaker locus to the long arm of the rat X chromosome. In this work, we

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db67cdb69c527324328f8e3b1abba267
https://doi.org/10.1101/2022.03.28.486143

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Current Opinions and Consensus for Studying Tremor in Animal Models

Publikováno v: Cerebellum

Tremor is the most common movement disorder; however, we are just beginning to understand the brain circuitry that generates tremor. Various neuroimaging, neuropathological, and physiological studies in human tremor disorders have been performed to f

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd9875072fd92889c60b34121078cfdc
https://doi.org/10.1007/s12311-019-01037-1

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Computational investigation of the impact of deep brain stimulation contact size and shape on neural selectivity

Autor: Daria Nesterovich Anderson, Collin J. Anderson, Stefan M. Pulst, John D. Rolston, Alan D. Dorval

Publikováno v: J Neural Eng

BACKGROUND. Understanding neural selectivity is essential for optimizing medical applications of deep brain stimulation (DBS). We previously showed that modulation of the DBS waveform can induce changes in orientation-based selectivity, and that leng

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a84c9264c952abc36ef58d6986129803
https://doi.org/10.1088/1741-2552/abeeaa

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Case Report of Lambert Eaton Myasthenic Syndrome in a Patient with Small Cell Lung Cancer on Immune Checkpoint Inhibitor Therapy

Autor: Amanda C. Guidon, Michael K. Hehir, Farrah B. Khan, Carolyne Riehle, Collin J. Anderson, Noah Kolb, Alissa A. Thomas

Publikováno v: OBM Neurobiology. 5

Lambert Eaton myasthenic syndrome (LEMS) is a rare autoimmune neuromuscular junction disorder involving loss of functional pre-synaptic P/Q-type voltage-gated calcium channels. Many cases occur as a paraneoplastic disorder, often in small cell lung c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8e16307709db951caa6b3cc244d94f85
https://doi.org/10.21926/obm.neurobiol.2101086

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Detecting and Quantifying Ataxia-Related Motor Impairments in Rodents Using Markerless Motion Tracking With Deep Neural Networks

Autor: Stefan M. Pulst, Collin J. Anderson, Eva Haas, Jana Lang, Jeannette Hübener-Schmid, Martin A. Giese, Winfried Ilg

Publikováno v: Annu Int Conf IEEE Eng Med Biol Soc
EMBC

In this study we evaluate the application of video-based markerless motion tracking based on deep neural networks for the analysis of ataxia-specific movement abnormalities in rodent models of cerebellar ataxia. Based on a small amount (

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a3b1ee3ca26ad1823fbe32ede729a96
https://pubmed.ncbi.nlm.nih.gov/33018791

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Defining the impact of deep brain stimulation contact size and shape on neural selectivity

Autor: Alan D. Dorval, Collin J. Anderson, Daria Nesterovich Anderson, Stefan M. Pulst, John D. Rolston

BackgroundUnderstanding neural selectivity is essential for optimizing medical applications of deep brain stimulation (DBS). We previously showed that modulation of the DBS waveform can induce changes in orientation-based selectivity, and that length

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::49b34abe1e2170e6eabccef4ac1fa6ba
https://doi.org/10.1101/2020.06.11.147157

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