Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Collin Chia"'
Autor:
Surajit Dey, Wenying Lu, Heinrich C. Weber, Collin Chia, Prabuddha S. Pathinayake, Peter A.B. Wark, Mathew Suji Eapen, Sukhwinder Singh Sohal
Publikováno v:
ERJ Open Research, Vol 10, Iss 4 (2024)
Externí odkaz:
https://doaj.org/article/6b30d2c786a040b292e813692a8578fc
Autor:
Prem Bhattarai, Wenying Lu, Ashutosh Hardikar, Surajit Dey, Archana Vijay Gaikwad, Affan Mahmood Shahzad, Collin Chia, Andrew Williams, Gurpreet Kaur Singhera, Tillie-Louise Hackett, Mathew Suji Eapen, Sukhwinder Singh Sohal
Publikováno v:
ERJ Open Research, Vol 10, Iss 1 (2024)
Background We have previously reported pulmonary arterial remodelling in smokers and patients with early COPD, which can be attributed to endothelial to mesenchymal transition (EndMT). In this study, we aimed to evaluate if EndMT is an active mechani
Externí odkaz:
https://doaj.org/article/bb5fe1dc35c645afbd125122e5bbbdf6
Autor:
Surajit Dey, Wenying Lu, Greg Haug, Collin Chia, Josie Larby, Heinrich C. Weber, Archana Vijay Gaikwad, Prem Bhattarai, Affan Mahmood Shahzad, Prabuddha S. Pathinayake, Peter A. B. Wark, Mathew Suji Eapen, Sukhwinder Singh Sohal
Publikováno v:
Respiratory Research, Vol 24, Iss 1, Pp 1-21 (2023)
Abstract Background Although asthma and chronic obstructive pulmonary disease (COPD) are two distinct chronic airway inflammatory diseases, they often co-exist in a patient and the condition is referred to as asthma-COPD overlap (ACO). Lack of eviden
Externí odkaz:
https://doaj.org/article/5e348fad49dd4876b16753136037991c
Autor:
Wenying Lu, Mathew Suji Eapen, Ashutosh Hardikar, Collin Chia, Iain Robertson, Gurpreet Kaur Singhera, Tillie L. Hackett, Sukhwinder Singh Sohal
Publikováno v:
ERJ Open Research, Vol 9, Iss 6 (2023)
Background Epithelial–mesenchymal transition (EMT) might be central to lung cancer development in smokers and COPD. We illustrate EMT changes in a broader demographic of patient groups who were diagnosed with nonsmall cell lung cancer (adenocarcino
Externí odkaz:
https://doaj.org/article/d565a218566142e5adbcfe18992f330c
Autor:
Samuel James Brake, Wenying Lu, Collin Chia, Greg Haug, Josie Larby, Ashutosh Hardikar, Gurpreet K. Singhera, Tillie L. Hackett, Mathew Suji Eapen, Sukhwinder Singh Sohal
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
BackgroundCOPD is a common disease characterized by respiratory airflow obstruction. TGF-β1 and SMAD pathway is believed to play a role in COPD pathogenesis by driving epithelial mesenchymal transition (EMT).MethodsWe investigated TGF-β1 signalling
Externí odkaz:
https://doaj.org/article/1785ac62c9de46619da72af6e7aa262d
Autor:
Archana Vijay Gaikwad, Wenying Lu, Surajit Dey, Prem Bhattarai, Greg Haug, Josie Larby, Collin Chia, Jade Jaffar, Glen Westall, Gurpreet Kaur Singhera, Tillie-Louise Hackett, Mathew Suji Eapen, Sukhwinder Singh Sohal
Publikováno v:
ERJ Open Research, Vol 9, Iss 2 (2023)
Background We have previously reported arterial remodelling in patients with idiopathic pulmonary fibrosis (IPF) and suggested that endothelial-to-mesenchymal transition (EndMT) might be central to these changes. This study aims to provide evidence f
Externí odkaz:
https://doaj.org/article/b49ad27c47024587a61b641213c727bf
Autor:
Prem Bhattarai, Wenying Lu, Archana Vijay Gaikwad, Surajit Dey, Collin Chia, Josie Larby, Greg Haug, Ashutosh Hardikar, Andrew Williams, Gurpreet Kaur Singhera, Tillie-Louise Hackett, Mathew Suji Eapen, Sukhwinder Singh Sohal
Publikováno v:
ERJ Open Research, Vol 8, Iss 4 (2022)
Introduction Pulmonary vascular remodelling in chronic obstructive pulmonary disease (COPD) has detrimental consequences for lung physiology. The aim of our study was to provide a comprehensive size-based morphometric quantification of pulmonary arte
Externí odkaz:
https://doaj.org/article/52836600fe7a4a06ad575edb484c53ab
Autor:
Fraser Brims, John Zalcberg, Sue Evans, Nick Pavlakis, Jennifer Philip, Ross Lawrenson, Susan Harden, Henry Marshall, Gavin M Wright, Paul Dawkins, Emily Stone, Shantelle Smith, Margaret Brand, Lisa Briggs, Lillian Leigh, Mark Brooke, Vanessa N Brunelli, Collin Chia, Mary Duffy, Tracy Leong, Dainik Patel, Nicole Rankin, Nimit Singhal, Rebecca Tay, Shalini Vinod, Morgan Windsor, David Leong, Rob G Stirling
Publikováno v:
BMJ Open, Vol 12, Iss 8 (2022)
Introduction Lung cancer is the leading cause of cancer mortality, comprising the largest national cancer disease burden in Australia and New Zealand. Regional reports identify substantial evidence-practice gaps, unwarranted variation from best pract
Externí odkaz:
https://doaj.org/article/4c1f01498a6343608d4ac0b034715ec9
Autor:
Archana Vijay Gaikwad, Wenying Lu, Surajit Dey, Prem Bhattarai, Collin Chia, Josie Larby, Greg Haug, Stephen Myers, Jade Jaffar, Glen Westall, Gurpreet Kaur Singhera, Tillie-Louise Hackett, James Markos, Mathew Suji Eapen, Sukhwinder Singh Sohal
Publikováno v:
ERJ Open Research, Vol 8, Iss 1 (2022)
Background Idiopathic pulmonary fibrosis (IPF) is a progressive, irreversible fibrotic interstitial lung disease. We performed size-based quantitation of pulmonary arterial remodelling in IPF and examined the role of endothelial-to-mesenchymal transi
Externí odkaz:
https://doaj.org/article/cf0b599125c9433998a32829faa4515e
Autor:
Archana Vijay Gaikwad, Wenying Lu, Surajit Dey, Prem Bhattarai, Collin Chia, Josie Larby, Greg Haug, Stephen Myers, Jade Jaffar, Glen Westall, Gurpreet Kaur Singhera, Tillie-Louise Hackett, James Markos, Mathew Suji Eapen, Sukhwinder Singh Sohal
Publikováno v:
ERJ Open Research. :00571-2021
BackgroundIPF is a progressive, irreversible fibrotic interstitial lung disease. We performed size-based quantitation of pulmonary arterial remodelling in IPF, examined the role of EndMT and effects on lung physiology.MethodsResected lung tissues fro