Výsledky vyhledávání - "Collin, Bowe"

Serum and Colonic Mucosal Immune Markers in Irritable Bowel Syndrome

Autor: Lin, Chang, Mopelola, Adeyemo, Iordanis, Karagiannides, Iordanis, Karagiannidis, Elizabeth J, Videlock, Collin, Bowe, Wendy, Shih, Angela P, Presson, Pu-Qing, Yuan, Galen, Cortina, Hua, Gong, Sharat, Singh, Arlene, Licudine, Minou, Mayer, Yvette, Tache, Charalabos, Pothoulakis, Emeran A, Mayer

Publikováno v: American Journal of Gastroenterology. 107:262-272

Low-grade colonic mucosal inflammation has been postulated to have an important role in the pathophysiology of irritable bowel syndrome (IBS). The objectives of this study were (i) to identify serum and tissue-based immunological and neuroendocrine m

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd302617a79161acff8723b084b7afc5
https://doi.org/10.1038/ajg.2011.423

Zobrazit plný text záznamu

Substance P (SP)-Neurokinin-1 Receptor (NK-1R) Alters Adipose Tissue Responses to High-Fat Diet and Insulin Action

Autor: Iordanes Karagiannides, Miriam A Nuno, Dimitris Stavrakis, James M. Bugni, Norma P. Gerard, Bao Lu, Susan E. Leeman, Kyriaki Bakirtzi, Efi Kokkotou, Tamara Pirtskhalava, James L. Kirkland, Charalabos Pothoulakis, Collin Bowe, Hamed Nayeb-Hashemi

Publikováno v: Endocrinology. 152:2197-2205

Peripheral administration of a specific neurokinin-1 receptor (NK-1R) antagonist to mice leads to reduced weight gain and circulating levels of insulin and leptin after high-fat diet (HFD). Here, we assessed the contribution of substance P (SP) and N

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::491032b5166b63e1ec34061256bec863
https://doi.org/10.1210/en.2010-1345

Zobrazit plný text záznamu

Effects of obesity on severity of colitis and cytokine expression in mouse mesenteric fat. Potential role of adiponectin receptor 1

Autor: Aristea Sideri, Violeta Arsenescu, Phillip Fleshner, Jerrold R. Turner, Dimitris Stavrakis, Collin Bowe, Razvan Arsenescu, Charalabos Pothoulakis, David Q. Shih, Iordanes Karagiannides

Publikováno v: Sideri, A; Stavrakis, D; Bowe, C; Shih, DQ; Fleshner, P; Arsenescu, V; et al.(2015). Effects of obesity on severity of colitis and cytokine expression in mouse mesenteric fat. Potential role of adiponectin receptor 1. American Journal of Physiology-Gastrointestinal and Liver Physiology, 308(7), G591-G604. doi: 10.1152/ajpgi.00269.2014. UCLA: Retrieved from: http://www.escholarship.org/uc/item/327448pb

© 2015 the American Physiological Society. In inflammatory bowel disease (IBD), obesity is associated with worsening of the course of disease. Here, we examined the role of obesity in the development of colitis and studied mesenteric fat-epithelial

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c20b4b623f1656fe426a66abd57207e8
https://pubmed.ncbi.nlm.nih.gov/25591865

Zobrazit plný text záznamu

Substance P promotes expansion of human mesenteric preadipocytes through proliferative and antiapoptotic pathways

Autor: James L. Kirkland, Charalabos Pothoulakis, Hon Wai Koon, Tamara Tchkonia, Tamara Pirtskhalava, Nino Giorgadze, Ho Kim, Thomas Thomou, Collin Bowe, Kara J. Gross, Iordanes Karagiannides

Publikováno v: American journal of physiology. Gastrointestinal and liver physiology. 296(5)

White adipose tissue is intimately involved in the regulation of immunity and inflammation. We reported that human mesenteric preadipocytes express the substance P (SP)-mediated neurokinin-1 receptor (NK-1R), which signals proinflammatory responses.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6201a2cdaefacfb49ae079f079f30724
https://pubmed.ncbi.nlm.nih.gov/19282377

Zobrazit plný text záznamu

Substance P-mediated expression of the pro-angiogenic factor CCN1 modulates the course of colitis

Autor: Alan C. Moss, Collin Bowe, Charalabos Pothoulakis, Dezheng Zhao, Hua Xu, Hon Wai Koon, Mary Pat Moyer

Publikováno v: The American journal of pathology. 173(2)

Substance P (SP) regulates important intestinal functions, such as mucosal permeability, motility, chloride secretion, and inflammation via the neurokinin-1 receptor (NK-1R). Previous reports showed that vascularization and expression of angiogenic f

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09d20c8e50ba5659d25d1fb6a42fce20
https://pubmed.ncbi.nlm.nih.gov/18599605

Zobrazit plný text záznamu

Substance P as a novel anti-obesity target

Autor: Efi Kokkotou, Yu-Hua Tseng, Daniel Torres, Charalabos Pothoulakis, Daniel Espinoza, Iordanes Karagiannides, Eugenia Carvalho, Collin Bowe

Publikováno v: Gastroenterology. 134(3)

Background & Aims: Substance P (SP) is an 11-amino acid peptide that belongs to the tachykinin family of peptides. SP acts in the brain and in the periphery as a neuropeptide, neurotransmitter, and hormone affecting diverse physiologic pathways, main

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d917501071c7476c44c56f1ae6adc6e
https://pubmed.ncbi.nlm.nih.gov/18325388

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání