Capability and dependency in the Newcastle 85+ cohort study. Projections of future care needs

Autor: von Zglinicki Thomas, Eccles Martin P, Robinson Louise A, Kingston Andrew, Davies Karen, Collerton Joanna C, Jagger Carol, Martin-Ruiz Carmen, James Oliver FW, Kirkwood Tom BL, Bond John

Publikováno v: BMC Geriatrics, Vol 11, Iss 1, p 21 (2011)

Abstract Background Little is known of the capabilities of the oldest old, the fastest growing age group in the population. We aimed to estimate capability and dependency in a cohort of 85 year olds and to project future demand for care. Methods Stru

Externí odkaz: https://doaj.org/article/8a3db84274f34cd6a3bfce58131d652d

Publisher Correction: A meta-analysis of genome-wide association studies identifies multiple longevity genes (Nature Communications, (2019), 10, 1, (3669), 10.1038/s41467-019-11558-2)

Autor: Deelen, Joris, Evans, Daniel S., Arking, Dan E., Tesi, Niccolò, Nygaard, Marianne, Liu, Xiaomin, Wojczynski, Mary K., Biggs, Mary L., van der Spek, Ashley, Atzmon, Gil, Ware, Erin B., Sarnowski, Chloé, Smith, Albert V., Seppälä, Ilkka, Cordell, Heather J., Dose, Janina, Amin, Najaf, Arnold, Alice M., Ayers, Kristin L., Barzilai, Nir, Becker, Elizabeth J., Beekman, Marian, Blanché, Hélène, Christensen, Kaare, Christiansen, Lene, Collerton, Joanna C., Cubaynes, Sarah, Cummings, Steven R., Davies, Karen, Debrabant, Birgit, Deleuze, Jean François, Duncan, Rachel, Faul, Jessica D., Franceschi, Claudio, Galan, Pilar, Gudnason, Vilmundur, Harris, Tamara B., Huisman, Martijn, Hurme, Mikko A., Jagger, Carol, Jansen, Iris, Jylhä, Marja, Kähönen, Mika, Karasik, David, Kardia, Sharon L.R., Kingston, Andrew, Kirkwood, Thomas B.L., Launer, Lenore J., Lehtimäki, Terho, Lieb, Wolfgang, Lyytikäinen, Leo Pekka, Martin-Ruiz, Carmen, Min, Junxia, Nebel, Almut, Newman, Anne B., Nie, Chao, Nohr, Ellen A., Orwoll, Eric S., Perls, Thomas T., Province, Michael A., Psaty, Bruce M., Raitakari, Olli T., Reinders, Marcel J.T., Robine, Jean Marie, Rotter, Jerome I., Sebastiani, Paola, Smith, Jennifer, Sørensen, Thorkild I.A., Taylor, Kent D., Uitterlinden, André G., van der Flier, Wiesje, van der Lee, Sven J., van Duijn, Cornelia M., van Heemst, Diana, Vaupel, James W., Weir, David, Ye, Kenny, Zeng, Yi, Zheng, Wanlin, Holstege, Henne, Kiel, Douglas P., Lunetta, Kathryn L., Slagboom, P. Eline, Murabito, Joanne M.

Publikováno v: Nature Communications, 12(1):2463. Nature Publishing Group
Deelen, J, Evans, D S, Arking, D E, Tesi, N, Nygaard, M, Liu, X, Wojczynski, M K, Biggs, M L, van der Spek, A, Atzmon, G, Ware, E B, Sarnowski, C, Smith, A V, Seppälä, I, Cordell, H J, Dose, J, Amin, N, Arnold, A M, Ayers, K L, Barzilai, N, Becker, E J, Beekman, M, Blanché, H, Christensen, K, Christiansen, L, Collerton, J C, Cubaynes, S, Cummings, S R, Davies, K, Debrabant, B, Deleuze, J-F, Duncan, R, Faul, J D, Franceschi, C, Galan, P, Gudnason, V, Harris, T B, Huisman, M, Hurme, M A, Jagger, C, Jansen, I, Jylhä, M, Kähönen, M, Karasik, D, Kardia, S L R, Kingston, A, Kirkwood, T B L, Launer, L J, Lehtimäki, T, Lieb, W, Lyytikäinen, L-P, Martin-Ruiz, C, Min, J, Nebel, A, Newman, A B, Nie, C, Nohr, E A, Orwoll, E S, Perls, T T, Province, M A, Psaty, B M, Raitakari, O T, Reinders, M J T, Robine, J-M, Rotter, J I, Sebastiani, P, Smith, J, Sørensen, T I A, Taylor, K D, Uitterlinden, A G, van der Flier, W, van der Lee, S J, van Duijn, C M, van Heemst, D, Vaupel, J W, Weir, D, Ye, K, Zeng, Y, Zheng, W, Holstege, H, Kiel, D P, Lunetta, K L, Slagboom, P E & Murabito, J M 2021, ' Publisher Correction : A meta-analysis of genome-wide association studies identifies multiple longevity genes (Nature Communications, (2019), 10, 1, (3669), 10.1038/s41467-019-11558-2) ', Nature Communications, vol. 12, no. 1, 2463 . https://doi.org/10.1038/s41467-021-22613-2
Deelen, J, Evans, D S, Arking, D E, Tesi, N, Nygaard, M, Liu, X, Wojczynski, M K, Biggs, M L, van der Spek, A, Atzmon, G, Ware, E B, Sarnowski, C, Smith, A V, Seppälä, I, Cordell, H J, Dose, J, Amin, N, Arnold, A M, Ayers, K L, Barzilai, N, Becker, E J, Beekman, M, Blanché, H L, Christensen, K, Christiansen, L, Collerton, J C, Cubaynes, S, Cummings, S R, Davies, K, Debrabant, B, Deleuze, J-F, Duncan, R, Faul, J D, Franceschi, C, Galan, P, Gudnason, V, Harris, T B, Huisman, M, Hurme, M A, Jagger, C, Jansen, I, Jylhä, M, Kähönen, M, Karasik, D, Kardia, S L R, Kingston, A, Kirkwood, T B L, Launer, L J, Lehtimäki, T, Lieb, W, Lyytikäinen, L-P, Martin-Ruiz, C, Min, J, Nebel, A, Newman, A B, Nie, C, Nohr, E A, Orwoll, E S, Perls, T T, Province, M A, Psaty, B M, Raitakari, O T, Reinders, M J T, Robine, J-M, Rotter, J I, Sebastiani, P, Smith, J, Sørensen, T I A, Taylor, K D, Uitterlinden, A G, van der Flier, W, van der Lee, S J, van Duijn, C M, van Heemst, D, Vaupel, J W, Weir, D, Ye, K, Zeng, Y, Zheng, W, Holstege, H, Kiel, D P, Lunetta, K L, Slagboom, P E & Murabito, J M 2021, ' Publisher Correction: A meta-analysis of genome-wide association studies identifies multiple longevity genes (Nature Communications, (2019), 10, 1, (3669), 10.1038/s41467-019-11558-2) ', Nature Communications, vol. 12, no. 1, 2463 . https://doi.org/10.1038/s41467-021-22613-2
Deelen, J, Evans, D S, Arking, D E, Tesi, N, Nygaard, M, Liu, X, Wojczynski, M K, Biggs, M L, van der Spek, A, Atzmon, G, Ware, E B, Sarnowski, C, Smith, A V, Seppälä, I, Cordell, H J, Dose, J, Amin, N, Arnold, A M, Ayers, K L, Barzilai, N, Becker, E J, Beekman, M, Blanché, H, Christensen, K, Christiansen, L, Collerton, J C, Cubaynes, S, Cummings, S R, Davies, K, Debrabant, B, Deleuze, J-F, Duncan, R, Faul, J D, Franceschi, C, Galan, P, Gudnason, V, Harris, T B, Huisman, M, Hurme, M A, Jagger, C, Jansen, I, Jylhä, M, Kähönen, M, Karasik, D, Kardia, S L R, Kingston, A, Kirkwood, T B L, Launer, L J, Lehtimäki, T, Lieb, W, Lyytikäinen, L-P, Martin-Ruiz, C, Min, J, Nebel, A, Newman, A B, Nie, C, Nohr, E A, Orwoll, E S, Perls, T T, Province, M A, Psaty, B M, Raitakari, O T, Reinders, M J T, Robine, J-M, Rotter, J I, Sebastiani, P, Smith, J, Sørensen, T I A, Taylor, K D, Uitterlinden, A G, van der Flier, W, van der Lee, S J, van Duijn, C M, van Heemst, D, Vaupel, J W, Weir, D, Ye, K, Zeng, Y, Zheng, W, Holstege, H, Kiel, D P, Lunetta, K L, Slagboom, P E & Murabito, J M 2021, ' Publisher Correction : A meta-analysis of genome-wide association studies identifies multiple longevity genes (Nature Communications, (2019), 10, 1, (3669), 10.1038/s41467-019-11558-2) ', Nature Communications, vol. 12, 2463 . https://doi.org/10.1038/s41467-021-22613-2

© 2021, The Author(s).The original version of this Article contained an error in Fig. 1c, in which the top SNP was incorrectly labelled ‘rs4293358’. The correct label is ‘rs429358’. This has been corrected in both the PDF and HTML versions o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::8e1c89e3de74bbcc866af4835f87366a
https://research.vumc.nl/en/publications/eebb35c2-1f44-47f3-b9db-f81f4301e69f

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Publisher Correction: A meta-analysis of genome-wide association studies identifies multiple longevity genes.

Autor: Deelen J; Max Planck Institute for Biology of Ageing, Cologne, Germany. Joris.Deelen@age.mpg.de.; Molecular Epidemiology, Department of Biomedical Data Sciences, Leiden University Medical Center, Leiden, The Netherlands. Joris.Deelen@age.mpg.de., Evans DS; California Pacific Medical Center Research Institute, San Francisco, CA, USA. DEvans@sfcc-cpmc.net., Arking DE; McKusick-Nathans Institute of Genetic Medicine, Department of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Tesi N; Alzheimer Center Amsterdam, Department of Neurology, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, Amsterdam UMC, Amsterdam, The Netherlands.; Department of Clinical Genetics, Amsterdam UMC, Amsterdam, The Netherlands.; Delft Bioinformatics Lab, Delft University of Technology, Delft, The Netherlands., Nygaard M; The Danish Aging Research Center, Department of Public Health, University of Southern Denmark, Odense C, Denmark., Liu X; BGI-Shenzhen, Shenzhen, China.; China National Genebank, BGI-Shenzhen, Shenzhen, China., Wojczynski MK; Division of Statistical Genomics, Department of Genetics, Washington University School of Medicine, Saint Louis, MO, USA., Biggs ML; Department of Biostatistics, University of Washington, Seattle, WA, USA.; Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, WA, USA., van der Spek A; Department of Epidemiology, Erasmus MC, Rotterdam, The Netherlands., Atzmon G; Department of Biology, Faculty of Natural Science, University of Haifa, Haifa, Israel.; Departments of Medicine and Genetics, Albert Einstein College of Medicine, Bronx, NY, USA., Ware EB; Institute for Social Research, Survey Research Center, University of Michigan, Ann Arbor, MI, USA., Sarnowski C; Department of Biostatistics, Boston University School of Public Health, Boston, MA, USA., Smith AV; School of Public Health, Department of Biostatistics, University of Michigan, Ann Arbor, MI, USA.; Icelandic Heart Association, Kópavogur, Iceland., Seppälä I; Department of Clinical Chemistry, Fimlab Laboratories and Finnish Cardiovascular Research Center-Tampere, Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland., Cordell HJ; Institute of Genetic Medicine, Newcastle University, Newcastle upon Tyne, UK., Dose J; Institute of Clinical Molecular Biology, Kiel University, Kiel, Germany., Amin N; Department of Epidemiology, Erasmus MC, Rotterdam, The Netherlands., Arnold AM; Department of Biostatistics, University of Washington, Seattle, WA, USA., Ayers KL; Sema4, a Mount Sinai venture, Stamford, CT, USA., Barzilai N; Departments of Medicine and Genetics, Albert Einstein College of Medicine, Bronx, NY, USA., Becker EJ; Bioinformatics Program, Boston University, Boston, MA, USA., Beekman M; Molecular Epidemiology, Department of Biomedical Data Sciences, Leiden University Medical Center, Leiden, The Netherlands., Blanché H; Fondation Jean Dausset-CEPH, Paris, France., Christensen K; The Danish Aging Research Center, Department of Public Health, University of Southern Denmark, Odense C, Denmark.; Clinical Biochemistry and Pharmacology, Odense University Hospital, Odense C, Denmark.; Department of Clinical Genetics, Odense University Hospital, Odense C, Denmark., Christiansen L; The Danish Aging Research Center, Department of Public Health, University of Southern Denmark, Odense C, Denmark.; Department of Clinical Immunology, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark., Collerton JC; Institute of Health & Society, Newcastle University, Newcastle upon Tyne, UK., Cubaynes S; MMDN, Univ. Montpellier, EPHE, Unité Inserm 1198, PSL Research University, Montpellier, France., Cummings SR; California Pacific Medical Center Research Institute, San Francisco, CA, USA., Davies K; Institute of Neuroscience, Newcastle University, Newcastle upon Tyne, UK., Debrabant B; Department of Public Health, University of Southern Denmark, Odense C, Denmark., Deleuze JF; Fondation Jean Dausset-CEPH, Paris, France.; Centre National de Recherche en Génomique Humaine, CEA-Institut de Biologie François Jacob, Evry, France., Duncan R; Institute of Health & Society, Newcastle University, Newcastle upon Tyne, UK.; Newcastle University Institute for Ageing, Newcastle University, Newcastle upon Tyne, UK., Faul JD; Institute for Social Research, Survey Research Center, University of Michigan, Ann Arbor, MI, USA., Franceschi C; Department of Applied Mathematics and Centre of Bioinformatics, Lobachevsky State University of Nizhny Novgorod, Nizhny Novgorod, Russia.; IRCCS Institute of Neurological Sciences of Bologna (ISNB), Bologna, Italy., Galan P; EREN, UMR U1153 Inserm/U1125 Inra/Cnam/Paris 13, Université Paris 13, CRESS, Bobigny, France., Gudnason V; Icelandic Heart Association, Kópavogur, Iceland.; Faculty of Medicine, University of Iceland, Reykjavik, Iceland., Harris TB; Laboratory of Epidemiology and Population Sciences, National Institute on Aging, NIH, Bethesda, MD, USA., Huisman M; Department of Epidemiology and Biostatistics, Vrije Universiteit Amsterdam, Amsterdam UMC, Amsterdam, The Netherlands.; Amsterdam Public Health Research Institute, Amsterdam, The Netherlands., Hurme MA; Department of Microbiology and Immunology, Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland., Jagger C; Institute of Health & Society, Newcastle University, Newcastle upon Tyne, UK.; Newcastle University Institute for Ageing, Newcastle University, Newcastle upon Tyne, UK., Jansen I; Alzheimer Center Amsterdam, Department of Neurology, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, Amsterdam UMC, Amsterdam, The Netherlands.; Department of Complex Trait Genetics, Center for Neurogenomics and Cognitive Research, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands., Jylhä M; Faculty of Social Sciences (Health Sciences) and Gerontology Research Center (GEREC), Tampere University, Tampere, Finland., Kähönen M; Department of Clinical Physiology, Tampere University Hospital and Finnish Cardiovascular Research Center-Tampere, Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland., Karasik D; Azrieli Faculty of Medicine, Bar Ilan University, Safed, Israel.; Hinda and Arthur Marcus Institute for Aging Research, Hebrew SeniorLife, Boston, MA, USA., Kardia SLR; School of Public Health, Epidemiology, University of Michigan, Ann Arbor, MI, USA., Kingston A; Institute of Health & Society, Newcastle University, Newcastle upon Tyne, UK.; Newcastle University Institute for Ageing, Newcastle University, Newcastle upon Tyne, UK., Kirkwood TBL; Newcastle University Institute for Ageing, Newcastle University, Newcastle upon Tyne, UK., Launer LJ; Laboratory of Epidemiology and Population Sciences, National Institute on Aging, NIH, Bethesda, MD, USA., Lehtimäki T; Department of Clinical Chemistry, Fimlab Laboratories and Finnish Cardiovascular Research Center-Tampere, Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland., Lieb W; Institute of Epidemiology and Biobank PopGen, Kiel University, Kiel, Germany., Lyytikäinen LP; Department of Clinical Chemistry, Fimlab Laboratories and Finnish Cardiovascular Research Center-Tampere, Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland., Martin-Ruiz C; Institute of Neuroscience, Newcastle University, Newcastle upon Tyne, UK., Min J; Institute of Translational Medicine, School of Medicine, Zhejiang University, Hangzhou, China., Nebel A; Institute of Clinical Molecular Biology, Kiel University, Kiel, Germany., Newman AB; Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA, USA., Nie C; BGI-Shenzhen, Shenzhen, China., Nohr EA; Research Unit of Gynecology and Obstetrics, Department of Clinical Research, University of Southern Denmark, Odense C, Denmark., Orwoll ES; Bone and Mineral Unit, Oregon Health Sciences University, Portland, OR, USA., Perls TT; Department of Medicine, Geriatrics Section, Boston Medical Center, Boston University School of Medicine, Boston, MA, USA., Province MA; Division of Statistical Genomics, Department of Genetics, Washington University School of Medicine, Saint Louis, MO, USA., Psaty BM; Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, WA, USA.; Department of Epidemiology, University of Washington, Seattle, WA, USA.; Department of Health Services, University of Washington, Seattle, WA, USA.; Kaiser Permanente Washington Health Research Institute, Seattle, WA, USA., Raitakari OT; Department of Clinical Physiology and Nuclear Medicine, Turku University Hospital, Turku, Finland.; Research Centre of Applied and Preventive Cardiovascular Medicine, University of Turku, Turku, Finland., Reinders MJT; Delft Bioinformatics Lab, Delft University of Technology, Delft, The Netherlands., Robine JM; MMDN, Univ. Montpellier, EPHE, Unité Inserm 1198, PSL Research University, Montpellier, France.; CERMES3, UMR CNRS 8211-Unité Inserm 988-EHESS-Université Paris Descartes, Paris, France., Rotter JI; Institute for Translational Genomics and Population Sciences, Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center, Torrance, CA, USA.; Division of Genetic Outcomes, Department of Pediatrics, Harbor-UCLA Medical Center, Torrance, CA, USA., Sebastiani P; Department of Biostatistics, Boston University School of Public Health, Boston, MA, USA., Smith J; Institute for Social Research, Survey Research Center, University of Michigan, Ann Arbor, MI, USA.; School of Public Health, Epidemiology, University of Michigan, Ann Arbor, MI, USA., Sørensen TIA; Novo Nordisk Foundation Center for Basic Metabolic Research, Section of Metabolic Genetics, and Department of Public Health, Section of Epidemiology, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen N, Denmark.; MRC Integrative Epidemiology Unit, Bristol University, Bristol, UK., Taylor KD; Institute for Translational Genomics and Population Sciences, Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center, Torrance, CA, USA.; Department of Pediatrics, Harbor-UCLA Medical Center, Torrance, CA, USA., Uitterlinden AG; Department of Epidemiology, Erasmus MC, Rotterdam, The Netherlands.; Department of Internal Medicine, Erasmus MC, Rotterdam, The Netherlands., van der Flier W; Alzheimer Center Amsterdam, Department of Neurology, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, Amsterdam UMC, Amsterdam, The Netherlands.; Department of Epidemiology and Biostatistics, Vrije Universiteit Amsterdam, Amsterdam UMC, Amsterdam, The Netherlands., van der Lee SJ; Alzheimer Center Amsterdam, Department of Neurology, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, Amsterdam UMC, Amsterdam, The Netherlands.; Department of Clinical Genetics, Amsterdam UMC, Amsterdam, The Netherlands., van Duijn CM; Department of Epidemiology, Erasmus MC, Rotterdam, The Netherlands.; Nuffield Department of Population Health, University of Oxford, Oxford, UK., van Heemst D; Department of Gerontology and Geriatrics, Leiden University Medical Center, Leiden, The Netherlands., Vaupel JW; Max Planck Institute for Demographic Research, Rostock, Germany., Weir D; Institute for Social Research, Survey Research Center, University of Michigan, Ann Arbor, MI, USA., Ye K; Department of Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, NY, USA., Zeng Y; Center for Healthy Aging and Development Studies, National School of Development and Raissun Institute for Advanced Studies, Peking University, Beijing, China.; Center for the Study of Aging and Human Development and Geriatrics Division, Medical School of Duke University, Durham, NC, USA., Zheng W; California Pacific Medical Center Research Institute, San Francisco, CA, USA., Holstege H; Alzheimer Center Amsterdam, Department of Neurology, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, Amsterdam UMC, Amsterdam, The Netherlands.; Department of Clinical Genetics, Amsterdam UMC, Amsterdam, The Netherlands.; Delft Bioinformatics Lab, Delft University of Technology, Delft, The Netherlands., Kiel DP; Hinda and Arthur Marcus Institute for Aging Research, Hebrew SeniorLife, Boston, MA, USA.; Department of Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA, USA.; Broad Institute of MIT & Harvard, Cambridge, MA, USA., Lunetta KL; Department of Biostatistics, Boston University School of Public Health, Boston, MA, USA., Slagboom PE; Molecular Epidemiology, Department of Biomedical Data Sciences, Leiden University Medical Center, Leiden, The Netherlands. P.Slagboom@lumc.nl., Murabito JM; NHLBI's and Boston University's Framingham Heart Study, Framingham, MA, USA. murabito@bu.edu.; Section of General Internal Medicine, Department of Medicine, Boston University School of Medicine, Boston, MA, USA. murabito@bu.edu.

Publikováno v: Nature communications [Nat Commun] 2021 Apr 23; Vol. 12 (1), pp. 2463. Date of Electronic Publication: 2021 Apr 23.