Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Colleen Satorius"'
Autor:
Elaine F. Remmers, Ahmet Gül, Yohei Kirino, Sofia A. Oliveira, Fahmida Ghaderibarmi, Bahar Sadeghi Abdollahi, Daniel L. Kastner, Mary Blake, Masaki Takeuchi, Michael J. Ombrello, Nobuhisa Mizuki, Yilmaz Ozyazgan, Massimo Gadina, Fereydoun Davatchi, Atsuhisa Ueda, Burak Erer, Julie Le, Vânia Francisco, Ilknur Tugal-Tutkun, Abdolhadi Nadji, Niloofar Mojarad Shafiee, Akira Meguro, Colleen Satorius, Farhad Shahram, Tatsukata Kawagoe, Yoshiaki Ishigatsubo, Emire Seyahi, Shigeaki Ohno, Duran Ustek, Inês Sousa
Publikováno v:
Nature genetics
Daniel Kastner, Elaine Remmers and colleagues perform an association study of Behcet's disease based on dense genotyping of immune-related loci. They identify new association signals near genes involved in host response to microbial exposure and exte
Autor:
Linda M. Scott, Glenn Cruse, Daniel L. Kastner, Kenneth K. Kidd, André Mégarbané, Ana Olivera, Andrew J. Pakstis, Myrna Medlej-Hashim, James C. Mullikin, A. Robin Eisch, Hirsh D. Komarow, R. Daniel Long, Avanti Desai, Dean D. Metcalfe, Steven E. Boyden, Michael L. Young, Eliane Chouery, Chyi-Chia Richard Lee, Colleen Satorius, Hyejeong Bolan
Publikováno v:
New England Journal of Medicine. 374:656-663
Patients with autosomal dominant vibratory urticaria have localized hives and systemic manifestations in response to dermal vibration, with coincident degranulation of mast cells and increased histamine levels in serum. We identified a previously unk
Autor:
Yoonhee Kim, Neslihan Abaci, Atilla Cakar, Colleen Satorius, Yohei Kirino, Zeliha Emrence, Ilknur Tugal-Tutkun, Daniel L. Kastner, Burak Erer, Nobuhisa Mizuki, F Sevgi Sacli, George Bertsias, Yilmaz Ozyazgan, Geryl Wood, Akira Meguro, Atsuhisa Ueda, Duran Ustek, Ahmet Gül, Michael J. Ombrello, Yoshiaki Ishigatsubo, Elaine F. Remmers, Mitsuhiro Takeno, Hidetoshi Inoko, Emire Seyahi
Publikováno v:
Nature genetics
Individuals with Behcet's disease suffer from episodic inflammation often affecting the orogenital mucosa, skin and eyes. To discover new susceptibility loci for Behcet's disease, we performed a genome-wide association study (GWAS) of 779,465 SNPs wi
Autor:
Marta E. Alarcón-Riquelme, Elaine F. Remmers, Lucy R. Wedderburn, Sampath Prahalad, Seza Ozen, Daniel L. Kastner, Rae S. M. Yeung, John F. Bohnsack, Elisa Docampo, Ioanna Tachmazidou, Rosenberg Am, Andrew Zeft, Ricardo Russo, Johannes Peter Haas, Yelda Bilginer, Xavier Estivill, Elizabeth Baskin, Stephen W. Scherer, Jane Park, Wendy Thomson, Buhm Han, Dalila Pinto, Carl D. Langefeld, Eleftheria Zeggini, Richard H. Duerr, Jean-Paul Achkar, Dirk Foell, Michael J. Ombrello, J Cobb, Sara Signa, Ahmet Gül, Jordi Anton, Sheila Knupp Feitosa de Oliveira, Marco Gattorno, Anne Hinksb, Alberto Martini, Kenneth M. Kaufman, Patricia Woo, Maria Odete Esteves Hilário, Norman T. Ilowite, Claudio Arnaldo Len, Paul I.W. de Bakker, Susan D. Thompson, M. Ilyas Kamboh, Alexei A. Grom, Elizabeth D. Mellins, Tobias Schwarza, Soumya Raychaudhuri, Leah C. Kottyan, Colleen Satorius
Publikováno v:
Ombrello, M J, Remmers, E F, Tachmazidou, I, Grom, A, Foell, D, Haas, J-P, Martini, A, Gattorno, M, Özen, S, Prahalad, S, Zeft, A S, Bohnsack, J F, Mellins, E D, Ilowite, N T, Russo, R, Len, C, Hilario, M O E, Oliveira, S, Yeung, R S M, Rosenberg, A, Wedderburn, L R, Anton, J, Schwarz, T, Hinks, A, Bilginer, Y, Park, J, Cobb, J, Satorius, C, Buhm Hand, Baskin, E, Signa, S, Duerr, R H, Achkar, J-P, Kamboh, M I, Kaufman, K, Kottyan, L C, Pinto, D, Scherer, S W, Alarcón-Riquelme, M E, Docampo, E, Estivill, X, Gül, A, de Bakker, P I W, Raychaudhuri, S, Langefeld, C D, Thompson, S, Zeggini, E, Thomson, W, Kastner, D L & Wood, P 2015, ' HLA-DRB1*11 and variants of the MHC class II locus are strong risk factors for systemic juvenile idiopathic arthritis. ' Proceedings of the National Academy of Sciences of the United States of America, vol. 112, no. 52, pp. 15970-15975 . https://doi.org/10.1073/pnas.1520779112
Proceedings of the National Academy of Sciences of the United States of America, 112(52), 15970
British Society of Pediatric and Adolescent Rheumatology (BSPAR) Study Group, Childhood Arthritis Prospective Study (CAPS) Group, Randomized Placebo Phase Study of Rilonacept in sJIA (RAPPORT) Investigators, Sparks-Childhood Arthritis Response to Medication Study (CHARMS) Group, Biologically Based Outcome Predictors in JIA (BBOP) Group, International Childhood Arthritis Genetics (INCHARGE) Consortium, Ombrello, M J, Remmers, E F, Tachmazidou, I, Grom, A, Foell, D, Haas, J-P, Martini, A, Gattorno, M, Özen, S, Prahalad, S, Zeft, A S, Bohnsack, J F, Mellins, E D, Ilowite, N T, Russo, R, Len, C, Hilario, M O E, Oliveira, S, Yeung, R S M, Rosenberg, A, Wedderburn, L R, Anton, J, Schwarz, T, Hinks, A, Bilginer, Y, Park, J, Cobb, J, Satorius, C, Buhm Hand, Baskin, E, Signa, S, Duerr, R H, Achkar, J-P, Kamboh, M I, Kaufman, K, Kottyan, L C, Pinto, D, Scherer, S W, Alarcón-Riquelme, M E, Docampo, E, Estivill, X, Gül, A, de Bakker, P I W, Raychaudhuri, S, Langefeld, C D, Thompson, S, Zeggini, E, Thomson, W, Kastner, D L & Wood, P 2015, ' HLA-DRB1*11 and variants of the MHC class II locus are strong risk factors for systemic juvenile idiopathic arthritis. ', Proceedings of the National Academy of Sciences of the United States of America, vol. 112, no. 52, pp. 15970-15975 . https://doi.org/10.1073/pnas.1520779112
Proceedings of the National Academy of Sciences of the United States of America, 112(52), 15970
British Society of Pediatric and Adolescent Rheumatology (BSPAR) Study Group, Childhood Arthritis Prospective Study (CAPS) Group, Randomized Placebo Phase Study of Rilonacept in sJIA (RAPPORT) Investigators, Sparks-Childhood Arthritis Response to Medication Study (CHARMS) Group, Biologically Based Outcome Predictors in JIA (BBOP) Group, International Childhood Arthritis Genetics (INCHARGE) Consortium, Ombrello, M J, Remmers, E F, Tachmazidou, I, Grom, A, Foell, D, Haas, J-P, Martini, A, Gattorno, M, Özen, S, Prahalad, S, Zeft, A S, Bohnsack, J F, Mellins, E D, Ilowite, N T, Russo, R, Len, C, Hilario, M O E, Oliveira, S, Yeung, R S M, Rosenberg, A, Wedderburn, L R, Anton, J, Schwarz, T, Hinks, A, Bilginer, Y, Park, J, Cobb, J, Satorius, C, Buhm Hand, Baskin, E, Signa, S, Duerr, R H, Achkar, J-P, Kamboh, M I, Kaufman, K, Kottyan, L C, Pinto, D, Scherer, S W, Alarcón-Riquelme, M E, Docampo, E, Estivill, X, Gül, A, de Bakker, P I W, Raychaudhuri, S, Langefeld, C D, Thompson, S, Zeggini, E, Thomson, W, Kastner, D L & Wood, P 2015, ' HLA-DRB1*11 and variants of the MHC class II locus are strong risk factors for systemic juvenile idiopathic arthritis. ', Proceedings of the National Academy of Sciences of the United States of America, vol. 112, no. 52, pp. 15970-15975 . https://doi.org/10.1073/pnas.1520779112
Systemic juvenile idiopathic arthritis (sJIA) is an often severe, potentially life-threatening childhood inflammatory disease, the pathophysiology of which is poorly understood. To determine whether genetic variation within the MHC locus on chromosom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cef15701e9a8cb2080ea7a73e7cb84ed
https://www.research.manchester.ac.uk/portal/en/publications/hladrb111-and-variants-of-the-mhc-class-ii-locus-are-strong-risk-factors-for-systemic-juvenile-idiopathic-arthritis(3c2e2540-0cf8-4275-a590-693aec444069).html
https://www.research.manchester.ac.uk/portal/en/publications/hladrb111-and-variants-of-the-mhc-class-ii-locus-are-strong-risk-factors-for-systemic-juvenile-idiopathic-arthritis(3c2e2540-0cf8-4275-a590-693aec444069).html
Autor:
Marwen Ghabra, Farida Fortune, Neslihan Abaci, Phaedon G. Kaklamanis, Oznur Aglar, Oliver J. Brand, John M O'Shea, Ahmet Gül, Benjamin D. Korman, Miles Stanford, Hulya Azakli, Colleen Satorius, Dongsik Bang, Young-Hun Cho, Ilknur Tugal-Tutkun, Elaine F. Remmers, Virginia G. Kaklamani, Gulsen Akman-Demir, Michael B. Dizon, Afet Akdag Kose, Burak Erer, Graham R. Wallace, Daniel L. Kastner, Duran Ustek, Massimo Gadina, Wei-Wei Chen, William E R Ollier, Christopher I. Amos, Aris Cakiris, Julie M. Le, Eldad Ben-Chetrit, Fulya Cosan, Michael J. Ombrello, Yohei Kirino, Zeliha Emrence, Gülsevim Azizlerli, Barbara Yang
Publikováno v:
Nature genetics
Behçet's disease is a genetically complex disease of unknown etiology characterized by recurrent inflammatory attacks affecting the orogenital mucosa, eyes and skin. We performed a genome-wide association study with 311,459 SNPs in 1,215 individuals
Publikováno v:
Biophysical Journal. 83:359-370
Kinetic analysis of contracting fast and slow rabbit muscle fibers in the presence of the tension inhibitor 2,3-butanedione monoxime suggests that regulatory light chain (RLC) phosphorylation up-regulates the flux of weakly attached cross-bridges ent
Autor:
Yoshiaki Ishigatsubo, Neslihan Abaci, Nobuhisa Mizuki, Ahmet Gül, Gustavo Gutierrez-Cruz, Daniel L. Kastner, Yoonhee Kim, Emire Seyahi, Hidetoshi Inoko, Yilmaz Ozyazgan, Ilknur Tugal-Tutkun, Burak Erer, Atsuhisa Ueda, Baishali Maskeri, Mitsuhiro Takeno, Elaine F. Remmers, Hong-Wei Sun, Akira Meguro, Alexander F. Wilson, Qing Zhou, Colleen Satorius, Duran Ustek, Serdal Ugurlu, Michael J. Ombrello, James C. Mullikin, Yohei Kirino
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 110(20)
Genome-wide association studies (GWAS) are a powerful means of identifying genes with disease-associated common variants, but they are not well-suited to detecting genes with disease-associated rare and low-frequency variants. In the current study of
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 181(2)
Somatic hypermutation (SHM) of Ig genes depends upon the deamination of C nucleotides in WRCY (W = A/T, R = A/G, Y = C/T) motifs by activation-induced cytidine deaminase (AICDA). Despite this, a large number of mutations occur in WA motifs that can b
Autor:
Neal D. Epstein, Abhiram Prasad, Toren Finkel, Colleen Satorius, Arshed A. Quyyumi, Arthur Li, Rita Mincemoyer
Publikováno v:
American journal of medical genetics. 86(1)
Patients with coronary artery disease (CAD) have impaired endothelial function in part due to an increase in vascular oxidant stress. p22phox, an essential component of the NADPH oxidase, is thought to play a critical role in the generation of supero
Publikováno v:
The Journal of Immunology. 178:LB46-LB46
Germinal center (GC) B cells express high levels of activation induced cytidine deaminase (AID) which targets WRC (W=A/T, R=A/G) motifs generating a uracil:guanidine mismatch. During somatic hypermutation (SHM) 76% of the mutations are attributed to