Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Colleen Pappas"'
Autor:
Brittany A. Larsen, Brandon S. Klinedinst, Scott T. Le, Colleen Pappas, Tovah Wolf, Nathan F. Meier, Ye‐Lim Lim, Auriel A. Willette
Publikováno v:
Obesity Science & Practice, Vol 8, Iss 5, Pp 641-656 (2022)
Abstract BACKGROUND Aging is characterized by body composition alterations, including increased visceral adiposity accumulation and bone loss. Alcohol consumption may partially drive these alterations, but findings are mixed. This study primarily aim
Externí odkaz:
https://doaj.org/article/4fe202b35155420a8cbd3f0de28fffca
Autor:
Auriel A. Willette, Sara A. Willette, Qian Wang, Colleen Pappas, Brandon S. Klinedinst, Scott Le, Brittany Larsen, Amy Pollpeter, Tianqi Li, Jonathan P. Mochel, Karin Allenspach, Nicole Brenner, Tim Waterboer
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-11 (2022)
Abstract Many risk factors have emerged for novel 2019 coronavirus disease (COVID-19). It is relatively unknown how these factors collectively predict COVID-19 infection risk, as well as risk for a severe infection (i.e., hospitalization). Among aged
Externí odkaz:
https://doaj.org/article/d6bb23701777496e9e4a3a5a3286f653
Autor:
Colleen Pappas, Brandon S. Klinedinst, Scott Le, Qian Wang, Brittany Larsen, Kelsey McLimans, Samuel N. Lockhart, Karin Allenspach‐Jorn, Jonathan P. Mochel, Auriel A. Willette, for the Alzheimer's Disease Neuroimaging Initiative
Publikováno v:
Alzheimer’s & Dementia: Translational Research & Clinical Interventions, Vol 6, Iss 1, Pp n/a-n/a (2020)
Abstract Introduction Glucose hypometabolism and tau formation are key features of Alzheimer's disease (AD). Less is known about the relationship between fasting glucose and regional tau accumulation. Methods Cerebrospinal fluid (CSF) glucose was lin
Externí odkaz:
https://doaj.org/article/4a64a0b3d34e45ada6072a775f7e5dfa
Autor:
Yuji Kaneko, Colleen Pappas, Teresita Malapira, Fernando Ĺ. Vale, Naoki Tajiri, Cesar V. Borlongan
Publikováno v:
Cellular Physiology and Biochemistry, Vol 41, Iss 3, Pp 947-959 (2017)
Background/Aims: Neuroinflammatory processes have been implicated in the pathophysiology of seizure/epilepsy. High mobility group box 1 (HMGB1), a non-histone DNA binding protein, behaves like an inflammatory cytokine in response to epileptogenic ins
Externí odkaz:
https://doaj.org/article/a856e9ae0ff74a42bf5ad25e56bc3bc0
Autor:
Jessica J. Matchynski-Franks, Colleen Pappas, Julien Rossignol, Tiffany Reinke, Kyle Fink, Andrew Crane, Alison Twite, Steven A. Lowrance, Cheng Song, Gary L. Dunbar Ph.D
Publikováno v:
Cell Transplantation, Vol 25 (2016)
Alzheimer's disease (AD) is characterized by a progressive loss of memory and other cognitive disturbances. The neuropathology of AD includes the major hallmarks of toxic amyloid-β oligomer accumulation and neurofibrillary tangles, as well as increa
Externí odkaz:
https://doaj.org/article/c2728c88abd34d7999f66831176d6b74
Autor:
Tianqi Li, Colleen Pappas, Brandon Klinedinst, Amy Pollpeter, Brittany Larsen, Nathan Hoth, Faith Anton, Qian Wang, Auriel A. Willette
Publikováno v:
Journal of Alzheimer's Disease. :1-10
Background: Insulin-like growth factor (IGF)-1 plays an important role in Alzheimer’s disease (AD) pathogenesis and increases disease risk. However, prior research examining IGF-1 levels and brain neural network activity is mixed. Objective: The pr
Autor:
Brittany A. Larsen, Brandon S. Klinedinst, Scott T. Le, Colleen Pappas, Tovah Wolf, Nathan F. Meier, Ye‐Lim Lim, Auriel A. Willette
Publikováno v:
Obesity Science & Practice. 8:641-656
BACKGROUND: Aging is characterized by body composition alterations, including increased visceral adiposity accumulation and bone loss. Alcohol consumption may partially drive these alterations, but findings are mixed. This study primarily aimed to in
Autor:
Auriel A Willette, Tianqi Li, Sara A Willette, Brittany A Larsen, Amy Pollpeter, Brandon S Klinedinst, Shannin Moody, Neil Barnett, Mohammadiarvejeh Parvin, Colleen Pappas, Mochel Jonathan, Karin Allenspach‐Jorn, Qian Wang
Publikováno v:
Alzheimer's & Dementia. 18
Autor:
Ana D. Collazo-Martinez, Qian Wang, Sara A. Willette, Brandon S. Klinedinst, Nathan Hoth, Colleen Pappas, Brittany Larsen, Robert Dantzer, Karin Allenspach, Scott T. Le, Auriel A. Willette, Jonathan P. Mochel, Amy Pollpeter, Tianqi Li
Publikováno v:
Brain Behav Immun
Background Depressive symptoms in Alzheimer’s disease (AD) predict worse cognitive and functional outcomes. Both AD and major depression inflammatory processes are characterized by shunted tryptophan metabolism away from serotonin (5-HT) and toward
Publikováno v:
Cerebral cortex (New York, N.Y. : 1991).
Aging is associated with brain iron accumulation, which has been linked to cognitive decline. However, how brain iron affects the structure and function of cognitive brain networks remains unclear. Here, we explored the possibility that iron load in