Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Colleen M. Woods"'
Autor:
Stephen J. Savarino, Michael G. Prouty, Julianne E. Rollenhagen, Greg Glenn, Larry Ellingsworth, Jing Hui Tian, Steven T. Poole, Colleen M. Woods, Mimi Guebre-Xabier, Aisling O’Dowd
Publikováno v:
Vaccine. 37:6134-6138
dscCfaE is a recombinant form of the CFA/I tip adhesin CfaE, expressed by a large proportion of enterotoxigenic E. coli (ETEC). It is highly immunogenic by the intranasal route in mice and Aotus nancymaae, protective against challenge with CFA/I+ ETE
Autor:
Chad K. Porter, David R. Tribble, Barbara DeNearing, Stephen J. Savarino, Robin McKenzie, Shannon L. Grahek, Aisling O'Dowd, Stephanie A. Sincock, Carl Brinkley, Steven T. Poole, Joseph H. Crabb, Colleen M. Woods, A. Louis Bourgeois, Hye Kim
Publikováno v:
The Journal of Infectious Diseases. 220:505-513
BackgroundEnterotoxigenic Escherichia coli (ETEC) commonly cause diarrhea in children living in developing countries and in travelers to those regions. ETEC are characterized by colonization factors (CFs) that mediate intestinal adherence. We assesse
Autor:
Colleen M. Woods, Michael J. Gregory, Stephen J. Savarino, Milton Maciel, Michael G. Prouty, Steven T. Poole, Julianne E. Rollenhagen, Stephanie A. Sincock, Ryan C. Maves, Michael G. Jobling, Randall K. Holmes, Annette L. McVeigh, Aisling O'Dowd
Publikováno v:
Infect Immun
Recent efforts to develop an enterotoxigenic Escherichia coli (ETEC) vaccine have focused on the antigenically conserved tip adhesins of colonization factors. We showed previously that intranasal immunization with dsc(19)CfaE, a soluble variant of th
Autor:
Chad K. Porter, Stephanie A. Sincock, Stephen J. Savarino, Joseph H. Crabb, Shannon L. Grahek, Colleen M. Woods, Joyce A. Cantrell, David R. Tribble, Robin McKenzie, A. Louis Bourgeois, Aisling O'Dowd, Carl Brinkley, Barbara DeNearing, Hye Kim, Steven T. Poole
Publikováno v:
The Journal of Infectious Diseases. 216:7-13
Background Tip-localized adhesive proteins of bacterial fimbriae from diverse pathogens confer protection in animal models, but efficacy in humans has not been reported. Enterotoxigenic Escherichia coli (ETEC) commonly elaborate colonization factors
Autor:
Daniel Emerling, William R. Schief, S.W. Scally, Jean-Philippe Julien, A. Bosch, Sebastian Rämisch, Hanjun Shin, Ngan Nguyen, Stephen J. Streatfield, C. Richter King, Jessica A. Chichester, Brandon McLeod, Wayne Volkmuth, Colleen M. Woods, Dongkyoon Kim, Kazutoyo Miura
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
Nature Communications
Nature Communications
Transmission-blocking vaccines have the potential to be key contributors to malaria elimination. Such vaccines elicit antibodies that inhibit parasites during their development in Anopheles mosquitoes, thus breaking the cycle of transmission. To date
Autor:
Aisling O'Dowd, Colleen M. Woods, Steven T. Poole, Eric R. Hall, Stephen J. Savarino, Stephanie A. Sincock, Gladys Nunez, Milagros Miller, Annette L. McVeigh, Nereyda Espinoza
Publikováno v:
Vaccine. 34:284-291
Enterotoxigenic Escherichia coli (ETEC) are the most common cause of bacterial diarrhea in young children in developing countries and in travelers. Efforts to develop an ETEC vaccine have intensified in the past decade, and intestinal colonization fa
Autor:
Stephanie A. Sincock, David R. Tribble, Chad K. Porter, A. Louis Bourgeois, Joyce A. Cantrell, Colleen M. Woods, Robin McKenzie, Peter J. Sebeny, Barbara DeNearing, Shannon L. Grahek, David A. Sack, Aisling O'Dowd, Stephen J. Savarino
Publikováno v:
The Journal of infectious diseases. 204(1)
Human challenges with enterotoxigenic Escherichia coli (ETEC) have broadened our understanding of this important enteropathogen. We report findings from the first challenge studies using ETEC-expressing colonization factor fimbria CS17 and CS19. LSN0