Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Colleen M Witt"'
Publikováno v:
PLoS Biology, Vol 3, Iss 10 (2005)
Externí odkaz:
https://doaj.org/article/ffa9de6e7f9d449e8dbf97330c972d55
Publikováno v:
PLoS Biology, Vol 3, Iss 6, p e160 (2005)
Development of many vertebrate tissues involves long-range cell migrations. In most cases, these migrations have been inferred from analysis of single time points and the migration process has not been directly observed and quantitated in real time.
Externí odkaz:
https://doaj.org/article/804870b1d0904a73b1323cfb91774db9
Publikováno v:
Mycopathologia. 167:307-314
Cryptococcus neoformans is an opportunistic fungal pathogen with a propensity to infect the central nervous system of immune compromised individuals causing life-threatening meningoencephalitis. Cryptococcal biofilms have been described as a protecti
Publikováno v:
Journal of Theoretical Biology. 249:384-394
T cell development occurs in the thymus throughout life. Recent experimental findings show that the seeding of the thymus by multi-potent stem cells from the bone marrow is periodic rather than continuous, as previously assumed. However it is well kn
Autor:
Miguel Jose-Yacaman, George Perry, Jieh Juen Yu, Germán Plascencia-Villa, Annette R. Rodriguez, James P. Chambers, Colleen M. Witt, M. Neal Guentzel, Bernard P. Arulanandam
The human pathogen Chlamydia pneumoniae has been implicated in chronic inflammatory diseases including type 2 diabetes. Therefore, we designed a study to evaluate pancreatic beta cells and mast cells during chlamydial infection. Our study revealed th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8435b5da4c654b8a771732175c9e38f0
https://europepmc.org/articles/PMC4533996/
https://europepmc.org/articles/PMC4533996/
Autor:
Kay Robbins, Colleen M. Witt
Publikováno v:
Seminars in Immunology. 17:421-430
The dynamic process of thymocyte migration can now be visualized in real-time and in the context of the native thymic environment. With improved computational resources, key information can be extracted from real-time imaging data and the migratory b
Publikováno v:
Journal of Experimental Medicine. 201:501-504
Immunological phenomena that were once deduced from genetic, biochemical, and in situ approaches are now being witnessed in living color, in three dimensions, and in real time. The information in time-lapse imaging can provide valuable mechanistic in
Autor:
Ellen A. Robey, Colleen M. Witt
Publikováno v:
Seminars in Immunology. 17:95-102
Developing T cells undergo long-range migrations in the thymus that are tightly linked to their developmental program. In this review, we discuss the anatomical positioning of developing T cells in the thymus, review what we know about how cells move
Autor:
Colleen M. Witt, Ellen A. Robey
Publikováno v:
The Journal of Experimental Medicine
T cell differentiation in the adult thymus depends on sequential interactions between lymphoid progenitors and stromal cells found in distinct regions of the cortex and medulla. Therefore, migration of T cell progenitors through distinct stromal envi
Publikováno v:
Molecular and Cellular Biology. 23:8637-8650
Although studies have shown that the Notch2 family member is critical for embryonic development, little is known concerning its role in hematopoiesis. In this study, we show that the effects of an activated form of Notch2 (N2IC) on the T-cell lineage