Zobrazeno 1 - 10
of 79
pro vyhledávání: '"Colleen L Forster"'
Autor:
Peng Liu, Jennifer B Paulson, Colleen L Forster, Samantha L Shapiro, Karen H Ashe, Kathleen R Zahs
Publikováno v:
PLoS ONE, Vol 10, Iss 5, p e0126317 (2015)
Amyloid plaques composed of β-amyloid (Aβ) protein are a pathological hallmark of Alzheimer's disease. We here report the generation and characterization of a novel transgenic mouse model of Aβ toxicity. The rTg9191 mice harbor a transgene encodin
Externí odkaz:
https://doaj.org/article/d5e49ffb28e44ff3b5acdc4a0130a87f
Publikováno v:
PLoS ONE, Vol 10, Iss 8, p e0136729 (2015)
The Rb and Pten tumor suppressor genes are important regulators of bone development and both are frequently mutated in the bone cancer osteosarcoma (OS). To determine if Rb1 and Pten synergize as tumor suppressor genes for osteosarcoma, we co-deleted
Externí odkaz:
https://doaj.org/article/34b836e40c194654aeac89eee276b929
Autor:
Sarah E Tarullo, Yuyu He, Claire Daughters, Todd P Knutson, Christine M Henzler, Matthew A Price, Ryan Shanley, Patrice Witschen, Cornelia Tolg, Rachael E Kaspar, Caroline Hallstrom, Lyubov Gittsovich, Megan L Sulciner, Xihong Zhang, Colleen L Forster, Carol A Lange, Oleg Shats, Michelle Desler, Kenneth H Cowan, Douglas Yee, Kathryn L Schwertfeger, Eva A Turley, James B McCarthy, Andrew C Nelson
Publikováno v:
The Journal of Pathology.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8b000ae59732a9e903afa72e86e0d31f
https://doi.org/10.1002/path.6082
https://doi.org/10.1002/path.6082
Autor:
David A. Largaespada, Nancy Ratner, Stephen C. Schmechel, Margaret R. Wallace, Aaron L. Sarver, Margaret H. Collins, Colleen L. Forster, Anthony E. Rizzardi, Vincent W. Keng, Brian R. Wahl, Leah K. Anderson, Amanda L. Halfond, Andrew D. Greeley, Caitlin B. Conboy, Kwangmin Choi, Branden S. Moriarity, Eric P. Rahrmann, Adrienne L. Watson
Supplementary Figure 4 - PDF file 111K, Reduction of Wnt signaling by β-catenin knockdown or GSK3B overexpression reduces tumor growth in xenograft models
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9bce1b4500ae8aa47f763841e42aa42b
https://doi.org/10.1158/2159-8290.22530711
https://doi.org/10.1158/2159-8290.22530711
Autor:
Jaime F. Modiano, Kerstin Lindblad-Toh, Matthew Breen, Elinor K. Karlsson, Jason Turner-Maier, Ross Swofford, Ingegerd Elvers, Colleen L. Forster, LeAnn Oseth, Paari Murugan, Michael A. Linden, Ashley J. Schulte, Nuojin Cheng, Yoon Tae Kim, Jung Min Song, Aaron L. Sarver, Rachael Thomas, Kate Megquier, Jong Hyuk Kim
Table S1. Demographic and pathological features of human patients with angiosarcoma Table S2. Demographic and pathological features of dogs with HSA Table S3. Primary antibodies for immunohistochemical evaluation Table S4. Gene ontology and biologica
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35ab93e5f9c6d85ffd7e05a785309457
https://doi.org/10.1158/1541-7786.22526675
https://doi.org/10.1158/1541-7786.22526675
Autor:
David A. Largaespada, Nancy Ratner, Stephen C. Schmechel, Margaret R. Wallace, Aaron L. Sarver, Margaret H. Collins, Colleen L. Forster, Anthony E. Rizzardi, Vincent W. Keng, Brian R. Wahl, Leah K. Anderson, Amanda L. Halfond, Andrew D. Greeley, Caitlin B. Conboy, Kwangmin Choi, Branden S. Moriarity, Eric P. Rahrmann, Adrienne L. Watson
Supplementary Table 2 - PDF 69K, QPCR primer sequences
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54f54fa0e01e8181316838630811d03c
https://doi.org/10.1158/2159-8290.22530705
https://doi.org/10.1158/2159-8290.22530705
Autor:
Daniel A. Vallera, Jaime F. Modiano, Kristy Pilbeam, Felix Oh, Kerstin Lindblad-Toh, Matthew Breen, Michael S. Henson, Jillian Walz, Jerry Froelich, Jong-Hyuk Kim, Colleen L. Forster, Stephen Schmechel, Jonathan C. Henriksen, Anthony E. Rizzardi, Deborah Todhunter, Kathleen Stuebner, Amber L. Winter, Aaron L. Sarver, Joseph S. Koopmeiners, Antonella Borgatti
Detailed Methods for Immunohistochemistry Detailed Description of the Canine Clinical Study eBAT Pharmacokinetics and Neutralizing Antibody Assays Supplementary Table 1. Correlation between patient covariates and death Supplementary Table 2: Patient
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97a4aa52c0607ee0942297b84a938356
https://doi.org/10.1158/1535-7163.22505770
https://doi.org/10.1158/1535-7163.22505770
Autor:
David A. Largaespada, Nancy Ratner, Stephen C. Schmechel, Margaret R. Wallace, Aaron L. Sarver, Margaret H. Collins, Colleen L. Forster, Anthony E. Rizzardi, Vincent W. Keng, Brian R. Wahl, Leah K. Anderson, Amanda L. Halfond, Andrew D. Greeley, Caitlin B. Conboy, Kwangmin Choi, Branden S. Moriarity, Eric P. Rahrmann, Adrienne L. Watson
Supplementary Figure 2 - PDF file 109K, Overexpression of activated β-catenin and knockdown of AXIN1 or GSK3B results in increased Wnt signaling and an induction of oncogenic properties in immortalized human Schwann cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e365a917fcd11f9e3331f28e9d12a11
https://doi.org/10.1158/2159-8290.22530717.v1
https://doi.org/10.1158/2159-8290.22530717.v1
Autor:
David A. Largaespada, Nancy Ratner, Stephen C. Schmechel, Margaret R. Wallace, Aaron L. Sarver, Margaret H. Collins, Colleen L. Forster, Anthony E. Rizzardi, Vincent W. Keng, Brian R. Wahl, Leah K. Anderson, Amanda L. Halfond, Andrew D. Greeley, Caitlin B. Conboy, Kwangmin Choi, Branden S. Moriarity, Eric P. Rahrmann, Adrienne L. Watson
Supplementary Table and Figure Legends-PDF file 123K, Supplementary Table and Figure Legends
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ccc12018854f2621735d0c850c71419
https://doi.org/10.1158/2159-8290.22530702.v1
https://doi.org/10.1158/2159-8290.22530702.v1
Autor:
Daniel A. Vallera, Jaime F. Modiano, Kristy Pilbeam, Felix Oh, Kerstin Lindblad-Toh, Matthew Breen, Michael S. Henson, Jillian Walz, Jerry Froelich, Jong-Hyuk Kim, Colleen L. Forster, Stephen Schmechel, Jonathan C. Henriksen, Anthony E. Rizzardi, Deborah Todhunter, Kathleen Stuebner, Amber L. Winter, Aaron L. Sarver, Joseph S. Koopmeiners, Antonella Borgatti
Sarcomas differ from carcinomas in their mesenchymal origin. Therapeutic advancements have come slowly, so alternative drugs and models are urgently needed. These studies report a new drug for sarcomas that simultaneously targets both tumor and tumor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4a17472aa6c47bead566c16a06a42417
https://doi.org/10.1158/1535-7163.c.6538177.v1
https://doi.org/10.1158/1535-7163.c.6538177.v1