Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Colleen Kowal"'
Autor:
Huai-Xiang Hao, Giordano Caponigro, Morvarid Mohseni, Tinya J. Abrams, Peter S. Hammerman, Juliet A. Williams, Jeffrey A. Engelman, Matthew J. LaMarche, Susan E. Moody, Matthew J. Meyer, Hui Gao, Karrie Wong, William D. Hastings, Silvia Goldoni, Ye Wang, Scott Delach, Colleen Kowal, Guizhi Yang, Xiamei Zhang, Alice Loo, Hongyun Wang, Hengyu Lu, Chen Liu
CSF1R-driven SHP2-dependent MAPK signaling in GDM-1 cells and SHP2 dependency of the viability in M-CSF-stimulated monocytes in the T cell co-culture assay, and the in vivo combination benefit in suppressing tumor associated macrophage by anti-PD-1 a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06731a1fc427831477507d6aebca12e0
https://doi.org/10.1158/1078-0432.22478133
https://doi.org/10.1158/1078-0432.22478133
Autor:
Huai-Xiang Hao, Giordano Caponigro, Morvarid Mohseni, Tinya J. Abrams, Peter S. Hammerman, Juliet A. Williams, Jeffrey A. Engelman, Matthew J. LaMarche, Susan E. Moody, Matthew J. Meyer, Hui Gao, Karrie Wong, William D. Hastings, Silvia Goldoni, Ye Wang, Scott Delach, Colleen Kowal, Guizhi Yang, Xiamei Zhang, Alice Loo, Hongyun Wang, Hengyu Lu, Chen Liu
Supplementary Figure Legend
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f4250d56edcf37820adc098681f1006
https://doi.org/10.1158/1078-0432.22478130
https://doi.org/10.1158/1078-0432.22478130
Autor:
Huai-Xiang Hao, Giordano Caponigro, Morvarid Mohseni, Tinya J. Abrams, Peter S. Hammerman, Juliet A. Williams, Jeffrey A. Engelman, Matthew J. LaMarche, Susan E. Moody, Matthew J. Meyer, Hui Gao, Karrie Wong, William D. Hastings, Silvia Goldoni, Ye Wang, Scott Delach, Colleen Kowal, Guizhi Yang, Xiamei Zhang, Alice Loo, Hongyun Wang, Hengyu Lu, Chen Liu
The synergy in the MAPK pathway suppression and anti-proliferation effect by KRASG12C inhibitor and TNO155.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::013172c44043cee447214f4abb7b9e85
https://doi.org/10.1158/1078-0432.22478136.v1
https://doi.org/10.1158/1078-0432.22478136.v1
Autor:
Peter K. Sorger, Juliet A. Williams, William R. Sellers, Hans Bitter, Jeffrey A. Engelman, Esther Kurth, Alice Loo, Ronald Meyer, Paul Fordjour, GiNell Elliott, Daniel P. Rakiec, Stacy Rivera, Caroline Bullock, Julie Muszynski, Colleen Kowal, David A. Ruddy, Margaret E. McLaughlin, Roberto Velazquez, Xiamei Zhang, John Green, Guizhi Yang, Joshua M. Korn, Hui Gao, Deborah Plana, Adam C. Palmer
Ovarian cancer cell lines do not reproduce the clinical association between BRCA loss of function and sensitivity to olaparib, but patient-derived ovarian tumor xenografts do.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4a8bdb0443db0d690f202fb6d397c35
https://doi.org/10.1158/0008-5472.22424928.v1
https://doi.org/10.1158/0008-5472.22424928.v1
Autor:
Peter K. Sorger, Juliet A. Williams, William R. Sellers, Hans Bitter, Jeffrey A. Engelman, Esther Kurth, Alice Loo, Ronald Meyer, Paul Fordjour, GiNell Elliott, Daniel P. Rakiec, Stacy Rivera, Caroline Bullock, Julie Muszynski, Colleen Kowal, David A. Ruddy, Margaret E. McLaughlin, Roberto Velazquez, Xiamei Zhang, John Green, Guizhi Yang, Joshua M. Korn, Hui Gao, Deborah Plana, Adam C. Palmer
Ovarian PDX raw growth and sequencing data.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed4d25989d00c86918a38bd7a3c59547
https://doi.org/10.1158/0008-5472.22424910
https://doi.org/10.1158/0008-5472.22424910
Autor:
Peter K. Sorger, Juliet A. Williams, William R. Sellers, Hans Bitter, Jeffrey A. Engelman, Esther Kurth, Alice Loo, Ronald Meyer, Paul Fordjour, GiNell Elliott, Daniel P. Rakiec, Stacy Rivera, Caroline Bullock, Julie Muszynski, Colleen Kowal, David A. Ruddy, Margaret E. McLaughlin, Roberto Velazquez, Xiamei Zhang, John Green, Guizhi Yang, Joshua M. Korn, Hui Gao, Deborah Plana, Adam C. Palmer
Candidate biomarkers are not independently prognostic of survival in primary ovarian tumor samples from TCGA.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::571218df64e392384c1eb90b15269506
https://doi.org/10.1158/0008-5472.22424922.v1
https://doi.org/10.1158/0008-5472.22424922.v1
Autor:
Peter K. Sorger, Juliet A. Williams, William R. Sellers, Hans Bitter, Jeffrey A. Engelman, Esther Kurth, Alice Loo, Ronald Meyer, Paul Fordjour, GiNell Elliott, Daniel P. Rakiec, Stacy Rivera, Caroline Bullock, Julie Muszynski, Colleen Kowal, David A. Ruddy, Margaret E. McLaughlin, Roberto Velazquez, Xiamei Zhang, John Green, Guizhi Yang, Joshua M. Korn, Hui Gao, Deborah Plana, Adam C. Palmer
Genomic landscape analysis of epithelial ovarian carcinoma of PDXs, patient tumors (TCGA) and cell lines (CCLE).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a53ec9fa68a58ce9c1d5944def743bca
https://doi.org/10.1158/0008-5472.22424925.v1
https://doi.org/10.1158/0008-5472.22424925.v1
Autor:
Huai-Xiang Hao, Giordano Caponigro, Morvarid Mohseni, Tinya J. Abrams, Peter S. Hammerman, Juliet A. Williams, Jeffrey A. Engelman, Matthew J. LaMarche, Susan E. Moody, Matthew J. Meyer, Hui Gao, Karrie Wong, William D. Hastings, Silvia Goldoni, Ye Wang, Scott Delach, Colleen Kowal, Guizhi Yang, Xiamei Zhang, Alice Loo, Hongyun Wang, Hengyu Lu, Chen Liu
Identification of the feedback activated RTK and the synergy in anti-proliferation effect by the combination of respective RTK inhibitors and dabrafenib plus trametinib in RKO and MDST8 cells.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e7cb8da75cd0e34edbe53dd9cde73d8
https://doi.org/10.1158/1078-0432.22478139
https://doi.org/10.1158/1078-0432.22478139
Autor:
Peter K. Sorger, Juliet A. Williams, William R. Sellers, Hans Bitter, Jeffrey A. Engelman, Esther Kurth, Alice Loo, Ronald Meyer, Paul Fordjour, GiNell Elliott, Daniel P. Rakiec, Stacy Rivera, Caroline Bullock, Julie Muszynski, Colleen Kowal, David A. Ruddy, Margaret E. McLaughlin, Roberto Velazquez, Xiamei Zhang, John Green, Guizhi Yang, Joshua M. Korn, Hui Gao, Deborah Plana, Adam C. Palmer
Advanced ovarian cancers are a leading cause of cancer-related death in women and are currently treated with surgery and chemotherapy. This standard of care is often temporarily successful but exhibits a high rate of relapse, after which, treatment o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::075a73ef2ce4a4d5935e44e4cefec0a0
https://doi.org/10.1158/0008-5472.c.6511893
https://doi.org/10.1158/0008-5472.c.6511893
Autor:
Huai-Xiang Hao, Giordano Caponigro, Morvarid Mohseni, Tinya J. Abrams, Peter S. Hammerman, Juliet A. Williams, Jeffrey A. Engelman, Matthew J. LaMarche, Susan E. Moody, Matthew J. Meyer, Hui Gao, Karrie Wong, William D. Hastings, Silvia Goldoni, Ye Wang, Scott Delach, Colleen Kowal, Guizhi Yang, Xiamei Zhang, Alice Loo, Hongyun Wang, Hengyu Lu, Chen Liu
Purpose:SHP2 inhibitors offer an appealing and novel approach to inhibit receptor tyrosine kinase (RTK) signaling, which is the oncogenic driver in many tumors or is frequently feedback activated in response to targeted therapies including RTK inhibi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23801ceeb7ba68ce8b8d9fedfdac102e
https://doi.org/10.1158/1078-0432.c.6529860
https://doi.org/10.1158/1078-0432.c.6529860