Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Colleen J. Wurden"'
Publikováno v:
Epilepsy Research. 52:79-83
Multiple studies suggest that phenytoin concentrations increase with CBZ co-medication. This study evaluated the hypothesis that CBZ and/or its major metabolite (CBZE) inhibit CYP2C19-mediated phenytoin metabolism using human liver microsomes and cDN
Autor:
RenéH. Levy, Colleen J. Wurden, Kenneth E. Thummel, Deanna L. Kroetz, Frank J. Gonzalez, Susan M. Klein, Bradley M. Kerr
Publikováno v:
Biochemical Pharmacology. 47:1969-1979
A number of drugs inhibit the metabolism of carbamazepine catalyzed by cytochrome P450, sometimes resulting in carbamazepine intoxication. However, there is little information available concerning the identity of the specific isoforms of P450 respons
Autor:
William Trager, Jean Marie Gillardin, Georges Olive, Marina Rousseau, Kent L. Kunze, Frances E. Bishop, Elisabeth Rey, Agnès Tran, Gary G. Mather, Francis Lepage, René H. Levy, J. Vincent, Colleen J. Wurden, Kenneth E. Thummel, Philippe d'Athis, Rita Labroo, Gérard Pons
Publikováno v:
Clinical pharmacology and therapeutics. 62(5)
Objective The spectrum of cytochrome P450 inhibition of stiripentol, a new anticonvulsant, was characterized in vitro and in vivo. Methods Stiripentol was incubated in vitro with (R)-warfarin, coumarin, (S)-warfarin, (S)-mephenytoin, bufuralol, p-nit
Publikováno v:
Epilepsia (Series 4); Oct2002 Supplement 7, Vol. 43, p1, 351p
Autor:
Tran, Agnès, Rey, Elisabeth, Pons, Gérard, Rousseau, Marina, d'Athis, Philippe, Olive, Georges, Mather, Gary G., Bishop, Frances E., Wurden, Colleen J., Labroo, Rita, Trager, William F., Kunze, Kent L., Thummel, Kenneth E., Vincent, Jean C., Gillardin, Jean-Marie, Lepage, Francis, Levy, René H.
Publikováno v:
Clinical Pharmacology & Therapeutics; Nov1997, Vol. 62 Issue 5, p490-504, 15p