Zobrazeno 1 - 10
of 96
pro vyhledávání: '"Colleen G Julian"'
Autor:
Benjamin J Ryan, Nadine B Wachsmuth, Walter F Schmidt, William C Byrnes, Colleen G Julian, Andrew T Lovering, Andrew W Subudhi, Robert C Roach
Publikováno v:
PLoS ONE, Vol 9, Iss 10, p e108788 (2014)
It is classically thought that increases in hemoglobin mass (Hbmass) take several weeks to develop upon ascent to high altitude and are lost gradually following descent. However, the early time course of these erythropoietic adaptations has not been
Externí odkaz:
https://doaj.org/article/90e889f7762f4134a3bff40e0bd5de15
Autor:
Andrew W Subudhi, Nicolas Bourdillon, Jenna Bucher, Christopher Davis, Jonathan E Elliott, Morgan Eutermoster, Oghenero Evero, Jui-Lin Fan, Sonja Jameson-Van Houten, Colleen G Julian, Jonathan Kark, Sherri Kark, Bengt Kayser, Julia P Kern, See Eun Kim, Corinna Lathan, Steven S Laurie, Andrew T Lovering, Ryan Paterson, David M Polaner, Benjamin J Ryan, James L Spira, Jack W Tsao, Nadine B Wachsmuth, Robert C Roach
Publikováno v:
PLoS ONE, Vol 9, Iss 3, p e92191 (2014)
An understanding of human responses to hypoxia is important for the health of millions of people worldwide who visit, live, or work in the hypoxic environment encountered at high altitudes. In spite of dozens of studies over the last 100 years, the b
Externí odkaz:
https://doaj.org/article/c923b4453ad34a8982e035a8ee50a6a2
Autor:
Abigail Bigham, Marc Bauchet, Dalila Pinto, Xianyun Mao, Joshua M Akey, Rui Mei, Stephen W Scherer, Colleen G Julian, Megan J Wilson, David López Herráez, Tom Brutsaert, Esteban J Parra, Lorna G Moore, Mark D Shriver
Publikováno v:
PLoS Genetics, Vol 6, Iss 9, p e1001116 (2010)
High-altitude hypoxia (reduced inspired oxygen tension due to decreased barometric pressure) exerts severe physiological stress on the human body. Two high-altitude regions where humans have lived for millennia are the Andean Altiplano and the Tibeta
Externí odkaz:
https://doaj.org/article/39cb3d049f7b49aca867b424e226bc0d
Autor:
Amanda K. Jones, Paul J. Rozance, Laura D. Brown, Ramón A. Lorca, Colleen G. Julian, Lorna G. Moore, Sean W. Limesand, Stephanie R. Wesolowski
Publikováno v:
Physiological Reports, Vol 9, Iss 18, Pp n/a-n/a (2021)
Abstract Gestational hypoxemia is often associated with reduced birth weight, yet how hypoxemia controls uteroplacental nutrient metabolism and supply to the fetus is unclear. This study tested the effects of maternal hypoxemia (HOX) between 0.8 and
Externí odkaz:
https://doaj.org/article/6d39b3d4d081446c8544893989d2a34f
Publikováno v:
American journal of physiology. Regulatory, integrative and comparative physiology. 323(5)
In healthy near-term women, blood flow to the uteroplacental circulation is estimated as 841 mL/min, which is greater than in other mammalian species. We argue that as uterine venous Po2 sets the upper limit for O2 diffusion to the fetus, high uterin
Publikováno v:
Frontiers in Oncology, Vol 9 (2020)
Lactate is a ubiquitous molecule in cancer. In this exploratory study, our aim was to test the hypothesis that lactate could function as an oncometabolite by evaluating whether lactate exposure modifies the expression of oncogenes, or genes encoding
Externí odkaz:
https://doaj.org/article/34090f45daff4f7fb6b8ca855fba9ea2
Autor:
Colleen G. Julian
Publikováno v:
Frontiers in Physiology, Vol 10 (2019)
In recent years, high-throughput genomic technologies and computational advancements have invigorated efforts to identify the molecular mechanisms regulating human adaptation to high altitude. Although exceptional progress regarding the identificatio
Externí odkaz:
https://doaj.org/article/2313acea8b324ab6ab99e4ffa7ea152c
Autor:
Hannah M. Kyllo, Dong Wang, Ramón A. Lorca, Colleen G. Julian, Lorna G. Moore, Randall B. Wilkening, Paul J. Rozance, Laura D. Brown, Stephanie R. Wesolowski
Publikováno v:
American Journal of Physiology-Endocrinology and Metabolism.
Glucose, lactate, and amino acids are major fetal nutrients. During placental insufficiency-induced intrauterine growth restriction (PI-IUGR), uteroplacental weight-specific oxygen consumption rates are maintained yet fetal glucose and amino acid sup
Publikováno v:
J Matern Fetal Neonatal Med
OBJECTIVES: To determine whether the full spectrum of hypertensive disorders of pregnancy (HDP) -- comprising gestational hypertension; preeclampsia with or without severe features; eclampsia; and Hemolysis, Elevated Liver enzymes, and Low Platelets
Autor:
William Mundo, Lilian Toledo-Jaldin, Alexandrea Heath-Freudenthal, Jaime Huayacho, Litzi Lazo-Vega, Alison Larrea-Alvarado, Valquiria Miranda-Garrido, Rodrigo Mizutani, Lorna G. Moore, Any Moreno-Aramayo, Richard Gomez, Patricio Gutierrez, Colleen G. Julian
Publikováno v:
High altitude medicinebiology. 23(4)
Mundo, William, Lilian Toledo-Jaldin, Alexandrea Heath-Freudenthal, Jaime Huayacho, Litzi Lazo-Vega, Alison Larrea-Alvarado, Valquiria Miranda-Garrido, Rodrigo Mizutani, Lorna G. Moore, Any Moreno-Aramayo, Richard Gomez, Patricio Gutierrez, and Colle