Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Colleen Fullenkamp"'
Autor:
Nicole Merritt, Keith Garcia, Dushyandi Rajendran, Zhen-Yuan Lin, Xiaomeng Zhang, Katrina A Mitchell, Nicholas Borcherding, Colleen Fullenkamp, Michael S Chimenti, Anne-Claude Gingras, Kieran F Harvey, Munir R Tanas
Publikováno v:
eLife, Vol 10 (2021)
Epithelioid hemangioendothelioma (EHE) is a vascular sarcoma that metastasizes early in its clinical course and lacks an effective medical therapy. The TAZ-CAMTA1 and YAP-TFE3 fusion proteins are chimeric transcription factors and initiating oncogeni
Externí odkaz:
https://doaj.org/article/f5236ab6208a49dc9d2f318dd8878eee
Autor:
Kelly N Messingham, Heather M Holahan, Alexandra S Frydman, Colleen Fullenkamp, Rupasree Srikantha, Janet A Fairley
Publikováno v:
PLoS ONE, Vol 9, Iss 9, p e107725 (2014)
Bullous pemphigoid (BP) is an autoimmune blistering disease mediated by autoantibodies targeting BP180 (type XVII collagen). Patient sera and tissues typically have IgG and IgE autoantibodies and elevated eosinophil numbers. Although the pathogenicit
Externí odkaz:
https://doaj.org/article/3cb22036c55947899d7cd3128ee634a2
Autor:
Zhen-Yuan Lin, Nicholas Borcherding, Munir R. Tanas, Colleen Fullenkamp, Katrina A. Mitchell, Nicole Merritt, Dushyandi Rajendran, Xiaomeng Zhang, Michael S. Chimenti, Keith Garcia, Anne-Claude Gingras, Kieran F. Harvey
Publikováno v:
eLife, Vol 10 (2021)
eLife
eLife
Epithelioid hemangioendothelioma (EHE) is a vascular sarcoma that metastasizes early in its clinical course and lacks an effective medical therapy. The TAZ-CAMTA1 and YAP-TFE3 fusion proteins are chimeric transcription factors and initiating oncogeni
Autor:
Dushyandi Rajendran, Keith Garcia, Xiaomeng Zhang, Zhen-Yuan Lin, Nicholas Borcherding, Anne-Claude Gingras, Michael S. Chimenti, Nicole Merritt, Katrina A. Mitchell, Colleen Fullenkamp, Kieran F. Harvey, Munir R. Tanas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::919c5e1ccac7bacf4fc8d2bfd8a0f175
https://doi.org/10.7554/elife.62857.sa2
https://doi.org/10.7554/elife.62857.sa2
Autor:
Anne-Claude Gingras, Munir R. Tanas, Xiaomeng Zhang, Colleen Fullenkamp, Nicole Merritt, Keith Garcia, Michael S. Chimenti, Kieran F. Harvey, Dushyandi Rajendran, Katrina M. Mitchell, Zhen-Yuan Lin, Nicholas Borcherding
Epithelioid hemangioendothelioma (EHE) is a vascular sarcoma that metastasizes early and lacks an effective medical therapy. The TAZ-CAMTA1 and YAP-TFE3 fusion proteins are chimeric transcription factors and initiating oncogenic drivers of EHE. A com
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a9abdb159814342e588eb2c8ade2c12c
https://doi.org/10.1101/2020.09.07.286633
https://doi.org/10.1101/2020.09.07.286633
Autor:
Chandni Desai, Jon Thomason, Qining Qian, Sarah L. Hall, Benjamin W. Darbro, Colleen Fullenkamp, Munir R. Tanas, Adam J. Dupuy, Nicole Merritt, Allyn M. Lambertz
Publikováno v:
Oncotarget
TAZ and YAP are transcriptional coactivators negatively regulated by the Hippo pathway that have emerged as key oncoproteins in several cancers including sarcomas. We hypothesized that loss of expression of the Hippo kinases might be a mechanism of a
Autor:
Benjamin J. Miller, Georgina K. Ofori-Amanfo, Mohammed M. Milhem, Johanna Savage, Colleen Fullenkamp, Erica C. Savage, Munir R. Tanas, Christopher S. Stipp, Stephanie D. Ivins, Omar I. Jaber, Brittany L. Pakalniskis, Sarah L. Hall, Allyn M. Lambertz
Publikováno v:
Oncotarget
TAZ (WWTR1) and YAP are transcriptional coactivators and oncoproteins inhibited by the Hippo pathway. Herein we evaluate 159 sarcomas representing the most prevalent sarcoma types by immunohistochemistry for expression and activation (nuclear localiz
Autor:
Munir R. Tanas, Nicole Merritt, Kieran F. Harvey, Xiaomeng Zhang, Colleen Fullenkamp, Zhen-Yuan Lin, Dushyandi Rajendran, Keith Garcia, Katrina A. Mitchell, Anne-Claude Gingras
Publikováno v:
Molecular Cancer Research. 18:B44-B44
Background: Epithelioid hemangioendothelioma (EHE) is a vascular sarcoma characterized by WWTR1(TAZ)-CAMTA1 (85%) and YAP1-TFE3 gene fusions (15%). The fusion proteins contain the N-terminus of TAZ and YAP, including their TEAD binding domains, fused
Autor:
Zhen-Yuan Lin, Katrina A. Mitchell, Xiaomeng Zhang, Colleen Fullenkamp, Kieran F. Harvey, Anne-Claude Gingras, Nicole Merritt, Dushyandi Rajendran, Munir R. Tanas
Publikováno v:
Cancer Research. 78:3359-3359
Introduction: Sarcomas are cancers that originate from mesenchymal-derived tissues and represent 1% of adult cancers and 15% of pediatric cancers. No effective medical therapy exists for sarcomas, and the 5-year survival of metastatic sarcomas is 16%
Autor:
Jon C. D. Houtman, Colleen Fullenkamp, Paul W. Naumann, Jonathan W. Heusel, Catherine A. Forbes, Anthony A. Scalzo, Natalya V. Guseva, Zuhair K. Ballas, Michael R. Shey
Publikováno v:
European Journal of Immunology. 40:2618-2631
Natural killer (NK) cell-mediated resistance to murine cytomegalovirus (MCMV) is controlled by allelic Ly49 receptors, including activating Ly49H (C57BL/6 strain) and inhibitory Ly49I (129 strain), which specifically recognize MCMV m157, a glycosylph