Zobrazeno 1 - 10
of 117
pro vyhledávání: '"Colleen Dunn"'
Publikováno v:
PLoS ONE, Vol 12, Iss 4, p e0175486 (2017)
We optically measured effects of orally available ivacaftor (Kalydeco®) on sweat rates of identified glands in 3 R117H subjects, each having a unique set of additional mutations, and compared them with 5 healthy control subjects tested contemporaneo
Externí odkaz:
https://doaj.org/article/bab51c2ebaf049ac8b2c7e1cfb55db0e
Autor:
Jeeyeon Kim, Miesha Farahmand, Colleen Dunn, Zoe Davies, Eric Frisbee, Carlos Milla, Jeffrey J Wine
Publikováno v:
PLoS ONE, Vol 11, Iss 10, p e0165254 (2016)
Beta-adrenergically-stimulated sweat rates determined by evaporimetry or by sweat bubble imaging are useful for measuring CFTR function because they provide a near-linear readout across almost the full range of CFTR function. They differentiate cysti
Externí odkaz:
https://doaj.org/article/63fab2c3cf4b440d9b4c2fb294ac9655
Autor:
Jessica E Char, Marlene H Wolfe, Hyung-Ju Cho, Il-Ho Park, Jin Hyeok Jeong, Eric Frisbee, Colleen Dunn, Zoe Davies, Carlos Milla, Richard B Moss, Ewart A C Thomas, Jeffrey J Wine
Publikováno v:
PLoS ONE, Vol 9, Iss 2, p e88564 (2014)
To determine if oral dosing with the CFTR-potentiator ivacaftor (VX-770, Kalydeco) improves CFTR-dependent sweating in CF subjects carrying G551D or R117H-5T mutations, we optically measured sweat secretion from 32-143 individually identified glands
Externí odkaz:
https://doaj.org/article/0401acd3a79e4cd98a0cdfc673e9e1c9
Autor:
Jeffrey J Wine, Jessica E Char, Jonathan Chen, Hyung-Ju Cho, Colleen Dunn, Eric Frisbee, Nam Soo Joo, Carlos Milla, Sara E Modlin, Il-Ho Park, Ewart A C Thomas, Kim V Tran, Rohan Verma, Marlene H Wolfe
Publikováno v:
PLoS ONE, Vol 8, Iss 10, p e77114 (2013)
To assess CFTR function in vivo, we developed a bioassay that monitors and compares CFTR-dependent and CFTR-independent sweat secretion in parallel for multiple (~50) individual, identified glands in each subject. Sweating was stimulated by intraderm
Externí odkaz:
https://doaj.org/article/b1ebef50c03b401e9418ca3fcc1b2069
Autor:
Christopher H. Goss, Sonya L. Heltshe, Natalie E. West, Michelle Skalland, Don B. Sanders, Raksha Jain, Tara L. Barto, Barbra Fogarty, Bruce C. Marshall, Donald R. VanDevanter, Patrick A. Flume, Gregory Omlor, Brenda Bourne, Dion Roberts, Vicki Roberts, Samya Nasr, Dawn Kruse, Rachel Linnemann, Tsion Hailemichael, Caralee Forseen, Heidi Stapp, Natalie West, S. Patel, A. Claudio, Jerimiah Lysinger, Amy Harmala, George Solomon, Latona Kersh, Karen Miller, Dixie Durham, Ahmet Uluer, Robert Fowler, Carla Frederick, Nadine Caci, Charlotte Teneback, Julie Sweet, Michael Parkins, Clare Smith, Jennifer Goralski, Kelsey Haywood, Patrick Flume, Caroline Brailsford, Dana Albon, Christie Aderholt, Kimberly McBennett, Cindy Schaefer, Alpa Patel, April Hunt, Lauren Schumacher, Hari Polenakovik, Linda Clark, Jerry Nick, Katie Poch, Dana Kissner, James Cahill, Jorge Lascano, Erin Silverman, John McArdle, Alison Champagne, Robert Vender, Lisa Allwein, Lance Cohen, Norma (Jean) Barton, Tara Barto, Ami Patel, Cynthia Brown, Nia Vorhees, Michael Crosser, Lawrence Scott, Alix Ashare, Barbara Rodgers, Robert Zanni, Lisa Koval, Andrew Braun, Sophia Chiron Stevens, Maria Tupayachi Ortiz, Patricia Graham, Julie Biller, Erin Hubertz, Kathryn Moffett, Tammy Clark, Rebecca Griffith, Nancy Martinez, Sabiha Hussain, Fei Chen, Marie Egan, Catalina Guzman, Janice Wang, Aileen Espinal, Patricia Walker, Anne Kukral, Emily DiMango, Sarah Fracasso Francis, Carlos Milla, Colleen Dunn, Subramanyam Chittivelu, Ashley Scott, Daniel Dorgan, Sharon Ng, Joseph Pilewski, Rose Lanzo, Nauman Chaudary, Ryan Hayden, Steven Scofield, Barb Johnson, Brian Morrissey, Brandt Robinson, Douglas Conrad, Jenna Mielke, Moira Aitken, Chami Sanlors, Ravi Nayak, Freda Branch, Daniel Rosenbluth, Molly Siegel, Anil Ghimire, Mary Forell, Cori Daines, Monica Varela, Leslie Couch, Rebekah Hibbard, Allen Dozor, Armando Ramirez, Victor Ortega, Kathryn Kennedy, David Fish, Karen Longtine
Publikováno v:
American Journal of Respiratory and Critical Care Medicine
Am J Respir Crit Care Med
Am J Respir Crit Care Med
RATIONALE: People with cystic fibrosis (CF) experience acute worsening of respiratory symptoms and lung function known as pulmonary exacerbations. Treatment with intravenous antimicrobials is common; however, there is scant evidence to support a stan
Autor:
Colleen Dunn
Publikováno v:
New Readings on Women and Early Medieval English Literature and Culture. :141-158
Autor:
Paul L. Bollyky, Sean P. Ryan, Alexander A. Yacob, Colleen Dunn, Carlos Milla, Jacquelyn Zirbes, Jayakumar Rajadas, Andrey V. Malkovskiy
Publikováno v:
Analytical Chemistry. 91:7929-7934
Improved methods are needed to reliably assess Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) function in vivo in light of recent therapeutic developments targeting the CFTR protein. Oral fluid from patients with cystic fibrosis (CF) and
Autor:
Haitham S. Al Ashry, Hugi Hilmisson, Yuenan Ni, Robert J. Thomas, Clete A. Kushida, Deborah A. Nichols, Eileen B. Leary, Pamela R. Hyde, Tyson H. Holmes, Daniel A. Bloch, William C. Dement, Rik Jadrnicek, Ric Miller, Usman Aijaz, Aamir Farooq, Darryl Thomander, Chia-Yu Cardell, Emily Kees, Michael E. Sorel, Oscar Carrillo, Tami Crabtree, Ray Balise, Tracy Kuo, Rhonda M. Wong, Pete Silva, Max Hirshkowitz, Alan Gevins, Gary Kay, Linda K. McEvoy, Cynthia S. Chan, Sylvan Green, Christian Guilleminault, David Claman, Stephen Brooks, Julianne Blythe, Jennifer Blair, Pam Simi, Ronelle Broussard, Emily Greenberg, Bethany Franklin, Amirah Khouzam, Sanjana Behari Black, Viola Arias, Romelyn Delos Santos, Tara Tanaka, Stuart F. Quan, James L. Goodwin, Wei Shen, Phillip Eichling, Rohit Budhiraja, Charles Wynstra, Cathy Ward, Colleen Dunn, Terry Smith, Dane Holderman, Michael Robinson, Osmara Molina, Aaron Ostrovsky, Jesus Wences, Sean Priefert, Julia Rogers, Megan Ruiter, Leslie Crosby, Richard D. Simon, Kevin Hurlburt, Michael Bernstein, Timothy Davidson, Jeannine Orock-Takele, Shelly Rubin, Phillip Smith, Erica Roth, Julie Flaa, Jennifer Schwartz, Anna Simon, Amber Randall, James K. Walsh, Paula K. Schweitzer, Anup Katyal, Rhody Eisenstein, Stephen Feren, Nancy Cline, Dena Robertson, Sheri Compton, Susan Greene, Kara Griffin, Janine Hall, Daniel J. Gottlieb, David P. White, Denise Clarke, Kevin Moore, Grace Brown, Paige Hardy, Kerry Eudy, Lawrence Epstein, Sanjay Patel
Publikováno v:
Annals of the American Thoracic Society. 18(5)
Rationale: The increased prevalence of obstructive sleep apnea (OSA) coincides with a severe shortage of sleep physicians. There is a need for widescale home-sleep-testing devices with accurate aut...
Publikováno v:
Journal of Cystic Fibrosis. 17:179-185
Background To determine in vivo effects of CFTR modulators on mutation S945L. Methods We measured effects of CFTR modulators on CFTR-dependent sweating (‘C-sweat') in two pancreatic sufficient cystic fibrosis (CF) subjects. S1 (S945L/G542X) took iv