Zobrazeno 1 - 10
of 315
pro vyhledávání: '"Colleen C Nelson"'
Autor:
Michelle L Maugham, Inge Seim, Patrick B Thomas, Gabrielle J Crisp, Esha T Shah, Adrian C Herington, Kristy A Brown, Laura S Gregory, Colleen C Nelson, Penny L Jeffery, Lisa K Chopin
Publikováno v:
PLoS ONE, Vol 13, Iss 11, p e0198495 (2018)
Ghrelin is a peptide hormone which, when acylated, regulates appetite, energy balance and a range of other biological processes. Ghrelin predominately circulates in its unacylated form (unacylated ghrelin; UAG). UAG has a number of functions independ
Externí odkaz:
https://doaj.org/article/075dfcd2b0854101a8510da856b3357e
Autor:
Charles L. Bidgood, Lisa K. Philp, Anja Rockstroh, Melanie Lehman, Colleen C. Nelson, Martin C. Sadowski, Jennifer H. Gunter
Publikováno v:
Cell Death and Disease, Vol 15, Iss 7, Pp 1-12 (2024)
Abstract Metabolic reprogramming and energetic rewiring are hallmarks of cancer that fuel disease progression and facilitate therapy evasion. The remodelling of oxidative phosphorylation and enhanced lipogenesis have previously been characterised as
Externí odkaz:
https://doaj.org/article/5811d1732bff4d279de2e125b6da8d03
Autor:
Mannan eNouri, Ellca eRatther, Nataly eStylianou, Colleen C Nelson, Brett G Hollier, Elizabeth D Williams
Publikováno v:
Frontiers in Oncology, Vol 4 (2014)
Androgens regulate biological pathways to promote proliferation, differentiation and survival of benign and malignant prostate tissue. Androgen receptor targeted therapies exploit this dependence and are used in advanced prostate cancer to control di
Externí odkaz:
https://doaj.org/article/a5e211f812b54d929e26e9e1d9ebd024
Publikováno v:
PLoS ONE, Vol 9, Iss 11, p e112122 (2014)
Weak cell-surface adhesion of cell lines to tissue culture surfaces is a common problem and presents technical limitations to the design of experiments. To overcome this problem, various surface coating protocols have been developed. However, a compa
Externí odkaz:
https://doaj.org/article/33b8e568550442799e47cad1c3fd3d72
Publikováno v:
PLoS ONE, Vol 7, Iss 8, p e42431 (2012)
BACKGROUND: Accumulated biological research outcomes show that biological functions do not depend on individual genes, but on complex gene networks. Microarray data are widely used to cluster genes according to their expression levels across experime
Externí odkaz:
https://doaj.org/article/d0c14c7b542c4eb08cc21c5b41939a56
Autor:
Shirly Sieh, Anna V Taubenberger, Simone C Rizzi, Martin Sadowski, Melanie L Lehman, Anja Rockstroh, Jiyuan An, Judith A Clements, Colleen C Nelson, Dietmar W Hutmacher
Publikováno v:
PLoS ONE, Vol 7, Iss 9, p e40217 (2012)
Biophysical and biochemical properties of the microenvironment regulate cellular responses such as growth, differentiation, morphogenesis and migration in normal and cancer cells. Since two-dimensional (2D) cultures lack the essential characteristics
Externí odkaz:
https://doaj.org/article/3ae1c03cc7664588b81ef6f282d896d5
Autor:
Patrick B. Thomas, Saeid Alinezhad, Andre Joshi, Katrina Sweeney, Brian W. C. Tse, Gregor Tevz, Stephen McPherson, Colleen C. Nelson, Elizabeth D. Williams, Ian Vela
Publikováno v:
Current Oncology, Vol 30, Iss 11, Pp 9437-9447 (2023)
Patient-derived xenograft (PDX) models have been established as important preclinical cancer models, overcoming some of the limitations associated with the use of cancer cell lines. The utility of prostate cancer PDX models has been limited by an ina
Externí odkaz:
https://doaj.org/article/21c1299ac58a487cb97e5ad972e9f1c4
Autor:
Reuben S.E. Young, Andrew P. Bowman, Elizabeth D. Williams, Kaylyn D. Tousignant, Charles L. Bidgood, Venkateswara R. Narreddula, Rajesh Gupta, David L. Marshall, Berwyck L.J. Poad, Colleen C. Nelson, Shane R. Ellis, Ron M.A. Heeren, Martin C. Sadowski, Stephen J. Blanksby
Publikováno v:
Cell Reports, Vol 34, Iss 6, Pp 108738- (2021)
Summary: Canonical fatty acid metabolism describes specific enzyme-substrate interactions that result in products with well-defined chain lengths, degree(s), and positions of unsaturation. Deep profiling of lipids across a range of prostate cancer ce
Externí odkaz:
https://doaj.org/article/27b8a1a8bbb5417e805cadd5a720a7a8
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 7, Iss 6, Pp 1731-1741 (2017)
The bone metastasis-derived PC3 and the lymph node metastasis-derived LNCaP prostate cancer cell lines are widely studied, having been described in thousands of publications over the last four decades. Here, we report short-read whole-genome sequenci
Externí odkaz:
https://doaj.org/article/4867ebe73c74490ca8a86827a84a2f53
Autor:
Colleen C. Nelson, Rohan A. Davis, Melanie Lehman, Maria Kavallaris, Brian Gabrielli, Anja Rockstroh, Martin C. Sadowski, Claire Levrier
HeLa-H2B-GFP cells were imaged using an Olympus IX81 (1 image/5 min for 24 h). Top panels: brightfield, bottom panels: GFP channel. 6-AA increased in a concentration-dependent manner mitotic duration, leading to cell death or asymmetric division. Sca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d089ae51ff6dd3909643e653283b08c
https://doi.org/10.1158/1535-7163.22507932.v1
https://doi.org/10.1158/1535-7163.22507932.v1