Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Colleen Barrick"'
Autor:
Gianluca Fulgenzi, Zhenyi Hong, Francesco Tomassoni-Ardori, Luiz F. Barella, Jodi Becker, Colleen Barrick, Deborah Swing, Sudhirkumar Yanpallewar, Brad St Croix, Jürgen Wess, Oksana Gavrilova, Lino Tessarollo
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-18 (2020)
Glucose metabolism is regulated by hypothalamic brain functions and factors produced by peripheral tissues. Here, the authors show that the regulator of food intake Brain-derived neurotrophic factor is also produced and secreted by muscle and stimula
Externí odkaz:
https://doaj.org/article/b80c90e12332437a928a3eef0743440d
Autor:
Francesco Tomassoni-Ardori, Gianluca Fulgenzi, Jodi Becker, Colleen Barrick, Mary Ellen Palko, Skyler Kuhn, Vishal Koparde, Maggie Cam, Sudhirkumar Yanpallewar, Shalini Oberdoerffer, Lino Tessarollo
Publikováno v:
eLife, Vol 8 (2019)
Brain-derived neurotrophic factor (BDNF) is a potent modulator of brain synaptic plasticity. Signaling defects caused by dysregulation of its Ntrk2 (TrkB) kinase (TrkB.FL) and truncated receptors (TrkB.T1) have been linked to the pathophysiology of s
Externí odkaz:
https://doaj.org/article/6be4432cf992446394ab3d65b077132c
Autor:
Jürgen Wess, Luiz Felipe Barella, Brad St. Croix, Sudhirkumar Yanpallewar, Jodi Becker, Gianluca Fulgenzi, Deborah A. Swing, Zhenyi Hong, Francesco Tomassoni-Ardori, Oksana Gavrilova, Colleen Barrick, Lino Tessarollo
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-18 (2020)
Nature Communications
Nature Communications
BDNF signaling in hypothalamic circuitries regulates mammalian food intake. However, whether BDNF exerts metabolic effects on peripheral organs is currently unknown. Here, we show that the BDNF receptor TrkB.T1 is expressed by pancreatic β-cells whe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f45e3c3df92a52d566e5b9fac3aead1d
https://doaj.org/article/b80c90e12332437a928a3eef0743440d
https://doaj.org/article/b80c90e12332437a928a3eef0743440d
Autor:
Gianluca Fulgenzi, Colleen Barrick, Francesco Tomassoni-Ardori, Lino Tessarollo, Sudhirkumar Yanpallewar
Publikováno v:
Exp Neurol
The pathophysiology of Amyotrophic Lateral Sclerosis (ALS), a disease caused by the gradual degeneration of motoneurons, is still largely unknown. Insufficient neurotrophic support has been cited as one of the causes of motoneuron cell death. Neurotr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da09af50cd66b3d67e54143aead0dfe4
https://europepmc.org/articles/PMC9229840/
https://europepmc.org/articles/PMC9229840/
Autor:
Lino Tessarollo, Francesco Tomassoni-Ardori, Jodi Becker, Colleen Barrick, Gianluca Fulgenzi, Vishal N. Koparde, Sudhirkumar Yanpallewar, Mary Ellen Palko, Skyler Kuhn, Maggie Cam, Shalini Oberdoerffer
Publikováno v:
eLife, Vol 8 (2019)
eLife
eLife
Brain-derived neurotrophic factor (BDNF) is a potent modulator of brain synaptic plasticity. Signaling defects caused by dysregulation of its Ntrk2 (TrkB) kinase (TrkB.FL) and truncated receptors (TrkB.T1) have been linked to the pathophysiology of s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::395fd1df188a71b19a171fae3c8449ce
https://elifesciences.org/articles/49673
https://elifesciences.org/articles/49673
Autor:
Vishal N. Koparde, Maggie Cam, Colleen Barrick, Sudhirkumar Yanpallewar, Mary Ellen Palko, Skyler Kuhn, Francesco Tomassoni-Ardori, Lino Tessarollo, Jodi Becker, Gianluca Fulgenzi, Shalini Oberdoerffer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9eb747b7984a1405e2792503e67388f0
https://doi.org/10.7554/elife.49673.027
https://doi.org/10.7554/elife.49673.027
Autor:
Gianluca Fulgenzi, Sandrine Puverel, Lucia Babini, Lino Tessarollo, Jodi Becker, Francesco Tomassoni-Ardori, Colleen Barrick
Publikováno v:
The Journal of Cell Biology
BDNF exerts inotropic function in the adult mammalian heart through TrkB.T1 receptor and loss of this ligand/receptor system in cardiomyocytes impairs calcium signaling and causes cardiomyopathy, suggesting an essential physiological role for this pa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a24001b9cfb265058fbd58136d0e0681
https://doi.org/10.1083/jcb.201502100
https://doi.org/10.1083/jcb.201502100
Autor:
Colleen Barrick, Yuya Kunisaki, Christoph Scheiermann, Lino Tessarollo, Daniel Lucas, Paul S. Frenette, Andrew Chow, Ingmar Bruns
Publikováno v:
Nature Medicine, Vol. 19, No 6 (2013) pp. 695-703
Anticancer chemotherapy drugs challenge hematopoietic tissues to regenerate but commonly produce long-term sequelae. Chemotherapy-induced deficits in hematopoietic stem or stromal cell function have been described, but the mechanisms mediating hemato
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3c54e3f4b8a716f7c06e524eaca53c8
https://doi.org/10.1038/nm.3155
https://doi.org/10.1038/nm.3155
Autor:
Ryan M. Wyatt, Sandra Ott, Kevan M. Shokat, Xinyue Liu, Cynthia L. Renn, Naomi Sengamalay, Carmen C. Leitch, Richard M. Lovering, Claire M. Fraser-Liggett, Chao Zhang, Abhishek Pratap, Rita J. Balice-Gordon, Gianluca Fulgenzi, Jodi Becker, Christopher W. Ward, Lino Tessarollo, Kristie M. Jones, Robert J. Talmadge, Luke J. Tallon, Colleen Barrick, Lisa Sadzewicz, Kevin A. Voelker, Brandon K. Harvey, Susan G. Dorsey, Elizabeth Vernon-Pitts
Publikováno v:
American Journal of Physiology-Cell Physiology. 302:C141-C153
Neurotrophin-dependent activation of the tyrosine kinase receptor trkB.FL modulates neuromuscular synapse maintenance and function; however, it is unclear what role the alternative splice variant, truncated trkB ( trkB.T1), may have in the peripheral
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e240057d766f44c19d96df5763548515
https://doi.org/10.1152/ajpcell.00469.2010
https://doi.org/10.1152/ajpcell.00469.2010
Publikováno v:
Development. 138:2511-2521
RanBPM is a recently identified scaffold protein that links and modulates interactions between cell surface receptors and their intracellular signaling pathways. RanBPM has been shown to interact with a variety of functionally unrelated proteins; how
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e1505a7d35217030a5eb5042416b427
https://doi.org/10.1242/dev.062505
https://doi.org/10.1242/dev.062505