Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Colleen A. McHugh"'
Autor:
Cameron A. Burnett, Ashley T. Wong, Carlos A. Vasquez, Colleen A. McHugh, Gene W. Yeo, Alexis C. Komor
Publikováno v:
Frontiers in Genome Editing, Vol 4 (2022)
Base editors (BEs) are genome editing agents that install point mutations with high efficiency and specificity. Due to their reliance on uracil and inosine DNA damage intermediates (rather than double-strand DNA breaks, or DSBs), it has been hypothes
Externí odkaz:
https://doaj.org/article/37e53c2e41c141609f3005612da1186e
Publikováno v:
Earth's Future, Vol 11, Iss 12, Pp n/a-n/a (2023)
Abstract The frequency and intensity of heat extremes over the United States have increased since the mid‐20th century and are projected to increase with additional anthropogenic greenhouse gas forcing. We define heat extremes as summertime (June
Externí odkaz:
https://doaj.org/article/bb3d9fdfcd0443bb956ff40418da461f
Publikováno v:
Methods in Molecular Biology ISBN: 9781071631904
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f80f7500fba8ee92dc0d0f60e2e66408
https://doi.org/10.1007/978-1-0716-3191-1_16
https://doi.org/10.1007/978-1-0716-3191-1_16
Publikováno v:
Cancer Research. 83:3745-3745
Long non-coding RNAs (lncRNAs) control numerous biological processes, including epigenetic regulation, gene expression, proliferation and metabolism. However, the detailed biological mechanisms by which lncRNAs regulate cellular processes are still p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ea4014470aa989f6210274ead69c4328
https://doi.org/10.1158/1538-7445.am2023-3745
https://doi.org/10.1158/1538-7445.am2023-3745
Autor:
Mitchell Guttman, Colleen A. McHugh
Publikováno v:
Methods in Molecular Biology ISBN: 9781493972128
RNA molecules interact with proteins to perform a variety of functions in living cells. The binding partners of many RNAs, in particular the newly discovered class of long noncoding RNAs (lncRNAs), remain largely unknown. RNA antisense purification c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5fcbc7b9f21359165e168e491c5e9f39
https://doi.org/10.1007/978-1-4939-7213-5_31
https://doi.org/10.1007/978-1-4939-7213-5_31
Autor:
Colleen A, McHugh, Mitchell, Guttman
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 1649
RNA molecules interact with proteins to perform a variety of functions in living cells. The binding partners of many RNAs, in particular the newly discovered class of long noncoding RNAs (lncRNAs), remain largely unknown. RNA antisense purification c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5bb5b2d0b6fa7391cc95ae78447e5733
https://pubmed.ncbi.nlm.nih.gov/29130217
https://pubmed.ncbi.nlm.nih.gov/29130217
Publikováno v:
Molecular Microbiology. 80:1031-1051
Summary Bactofilins are fibre-forming bacterial cytoskeletal proteins. Here, we report the structural and biochemical characterization of MXAN_7475 (BacM), one of the four bactofilins of Myxococcus xanthus. Absence of BacM leads to a characteristic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5ede07788c39c04bebcca665cd659889
https://doi.org/10.1111/j.1365-2958.2011.07629.x
https://doi.org/10.1111/j.1365-2958.2011.07629.x
Autor:
Colleen A. McHugh, Martin Devenport, John R. Yates, M. Donnelly-Doman, Laurence Florens, Marcelo Jacobs-Lorena, Daniel J. Carucci, Jeffrey R. Johnson, Rhoel R. Dinglasan
Publikováno v:
Insect Biochemistry and Molecular Biology. 39:125-134
Malaria is a devastating disease. For transmission to occur, Plasmodium, the causative agent of malaria, must complete a complex developmental cycle in its mosquito vector. Thus, the mosquito is a potential target for disease control. Plasmodium ooki
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62858c4efd0ba2efe5d89347e2a6a239
https://doi.org/10.1016/j.ibmb.2008.10.010
https://doi.org/10.1016/j.ibmb.2008.10.010
Autor:
Christine Surka, Chun-Kan Chen, Julia Su, Sonja Hess, Christina Burghard, Mitchell Guttman, Michael J. Sweredoski, Kathrin Plath, Colleen A. McHugh, Eric S. Lander, Mario Blanco, Patrick McDonel, Amy Y. M. Chow, Amy Pandya-Jones, Annie Moradian, Christina Tran, Alexander A. Shishkin
Publikováno v:
PMC
Nature
Nature, vol 521, iss 7551
Nature
Nature, vol 521, iss 7551
Many long non-coding RNAs (lncRNAs) affect gene expression, but the mechanisms by which they act are still largely unknown. One of the best-studied lncRNAs is Xist, which is required for transcriptional silencing of one X chromosome during developmen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d74ecd79b2194665bca139bd00dee6f
http://hdl.handle.net/1721.1/106883
http://hdl.handle.net/1721.1/106883
Autor:
Naiqian Cheng, Juan Fontana, Egbert Hoiczyk, Daniel Nemecek, Colleen A. McHugh, Joseph S. Wall, Anastasia A. Aksyuk, Alasdair C. Steven, Dennis C. Winkler, J. Bernard Heymann, Alan S Lam
Living cells compartmentalize materials and enzymatic reactions to increase metabolic efficiency. While eukaryotes use membrane-bound organelles, bacteria and archaea rely primarily on protein-bound nanocompartments. Encapsulins constitute a class of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::147b81f8a4272c73138e195428ac7864
https://europepmc.org/articles/PMC4195785/
https://europepmc.org/articles/PMC4195785/