Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Colleen A. Burns"'
Autor:
Ruslan Novosiadly, Malcolm A. Smith, Peter J. Houghton, James T. DeLigio, David Surguladze, Marie C. Prewett, Heinz H. Fiebig, Nina Zanella, Gregory P. Donoho, Colleen A. Burns, Ying Wang, Christopher B. Damoci, Dale L. Ludwig, Michael Amatulli, Amelie Forest
Supplemental Tables 1-2 & Figures 1-4. Supplemental Table 1. Total IR, IR-A, IR-B, IGF-IR, IGF-I and IGF-II mRNA expression in preclinical models of pediatric solid tumors. Supplemental Table 2. Patient-derived xenograft models of lung adenocarcinoma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a081c5e60efb4377fed1664d1b1a0c24
https://doi.org/10.1158/1541-7786.22511881.v1
https://doi.org/10.1158/1541-7786.22511881.v1
Autor:
Ruslan Novosiadly, Malcolm A. Smith, Peter J. Houghton, James T. DeLigio, David Surguladze, Marie C. Prewett, Heinz H. Fiebig, Nina Zanella, Gregory P. Donoho, Colleen A. Burns, Ying Wang, Christopher B. Damoci, Dale L. Ludwig, Michael Amatulli, Amelie Forest
Supplemental Information. This file contains Supplemental Materials and Methods, Tables and Figure Legends
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84c646aa5b0835e16453e5cd8af32839
https://doi.org/10.1158/1541-7786.22511884
https://doi.org/10.1158/1541-7786.22511884
Autor:
Douglas Burtrum, Helen Kotanides, Leyi Shen, Darin Chin, Ruslan D. Novosiadly, Amelie Forest, Rose Marie Sattler, Xinlei Chen, Yiwei Zhang, Michael Topper, David Surguladze, Jingxing Li, Jaafar N. Haidar, Ivan Inigo, Gregory D. Plowman, Colleen A. Burns, Lauren Boucher, Andreas Sonyi, Prachi Sharma, Michael Kalos, Dale L. Ludwig, Maria B. Lebron, Anthony Pennello, Carmine Carpenito, Juqun Shen
Publikováno v:
Molecular Cancer Therapeutics. 19:988-998
The CD137 receptor plays a key role in mediating immune response by promoting T cell proliferation, survival, and memory. Effective agonism of CD137 has the potential to reinvigorate potent antitumor immunity either alone or in combination with other
Autor:
David Surguladze, Dale L. Ludwig, Ying Wang, Gregory P. Donoho, Nina Zanella, Ruslan D. Novosiadly, Christopher B. Damoci, Malcolm A. Smith, Colleen A. Burns, James T. DeLigio, Marie Prewett, Heinz H. Fiebig, Michael Amatulli, Peter J. Houghton, Amelie Forest
Publikováno v:
Molecular Cancer Research. 13:1615-1626
Despite a recent shift away from anti–insulin-like growth factor I receptor (IGF-IR) therapy, this target has been identified as a key player in the resistance mechanisms to various conventional and targeted agents, emphasizing its value as a thera
Autor:
Timothy Bailey, Nick Loizos, Jason E. Toombs, David E. Gerber, Jennifer Malaby, Colleen A. Burns, Michael Peyton, Rolf A. Brekken, Inga J Duignan, Michael T. Dellinger, Puja Gupta
Publikováno v:
Molecular Cancer Therapeutics. 11:2473-2482
In lung cancer, platelet-derived growth factor receptor α (PDGFRα) is expressed frequently by tumor-associated stromal cells and by cancer cells in a subset of tumors. We sought to determine the effect of targeting stromal PDGFRα in preclinical lu
Publikováno v:
Active Learning in Higher Education. 13:191-201
The use of classroom capture systems (systems that capture audio and video footage of a lecture and attempt to replicate a classroom experience) is becoming increasingly popular at the university level. However, research on the effectiveness of class
Autor:
Scott W. Eastman, Swee-Seong Wong, Michael Topper, Thompson N. Doman, David Schaer, Jason Manro, Amaladas Nelusha, Sau-Chi Betty Yan, Ruslan D. Novosiadly, Gerald Hall, Julie Stewart, Michael Kalos, Victoria L. Peek, Any T. Pappas, Bruce W. Konicek, Jennifer R. Stephens, Beverly L. Falcon, Philip W. Iversen, Richard A. Walgren, Um L. Um, Kelly M. Credille, Colleen A. Burns
Publikováno v:
Cancer Research. 77:5590-5590
The combination of tumor targeted therapeutics with PD-L1 checkpoint blockade is being explored as a method to increase the clinical benefits of immunotherapy, and expand response to additional cancer types. Merestinib (Mer) is a kinase inhibitor tar
Publikováno v:
Science. 267:1491-1494
RNA encoding the B subunit of the alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) subtype of ionotropic glutamate receptor (GluR-B) undergoes a posttranscriptional modification in which a genomically encoded adenosine is represented a
Autor:
Andrew J. Dropsey, Amelie Forest, William John Feaver, Colleen Burns Burns, Nick Loizos, Jennifer Gruber, Xuemei Guo, Armando R. Irizarry, Marie Prewett, Ruslan D. Novosiadly, Timothy R. Mack
Publikováno v:
Molecular Cancer Therapeutics. 14:C129-C129
While FGFR4 and its ligand FGF19 represent a promising target for cancers in which FGF19 is overexpressed or gene amplified, inhibition of this pathway carries a potential toxicity risk due to the role of FGFR4 in bile acid homeostasis. Treatment wit
Publikováno v:
Optometry (St. Louis, Mo.). 76(5)
Background Leber's hereditary optic neuropathy (LHON) is a bilateral optic neuropathy of mitochondrial inheritance that produces significant painless, central vision loss and dyschromatopsia. LHON usually occurs in young males between the ages of 15