Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Colleen A. Burns"'
Autor:
Ruslan Novosiadly, Malcolm A. Smith, Peter J. Houghton, James T. DeLigio, David Surguladze, Marie C. Prewett, Heinz H. Fiebig, Nina Zanella, Gregory P. Donoho, Colleen A. Burns, Ying Wang, Christopher B. Damoci, Dale L. Ludwig, Michael Amatulli, Amelie Forest
Supplemental Tables 1-2 & Figures 1-4. Supplemental Table 1. Total IR, IR-A, IR-B, IGF-IR, IGF-I and IGF-II mRNA expression in preclinical models of pediatric solid tumors. Supplemental Table 2. Patient-derived xenograft models of lung adenocarcinoma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a081c5e60efb4377fed1664d1b1a0c24
https://doi.org/10.1158/1541-7786.22511881.v1
https://doi.org/10.1158/1541-7786.22511881.v1
Autor:
Ruslan Novosiadly, Malcolm A. Smith, Peter J. Houghton, James T. DeLigio, David Surguladze, Marie C. Prewett, Heinz H. Fiebig, Nina Zanella, Gregory P. Donoho, Colleen A. Burns, Ying Wang, Christopher B. Damoci, Dale L. Ludwig, Michael Amatulli, Amelie Forest
Supplemental Information. This file contains Supplemental Materials and Methods, Tables and Figure Legends
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84c646aa5b0835e16453e5cd8af32839
https://doi.org/10.1158/1541-7786.22511884
https://doi.org/10.1158/1541-7786.22511884
Autor:
Douglas Burtrum, Helen Kotanides, Leyi Shen, Darin Chin, Ruslan D. Novosiadly, Amelie Forest, Rose Marie Sattler, Xinlei Chen, Yiwei Zhang, Michael Topper, David Surguladze, Jingxing Li, Jaafar N. Haidar, Ivan Inigo, Gregory D. Plowman, Colleen A. Burns, Lauren Boucher, Andreas Sonyi, Prachi Sharma, Michael Kalos, Dale L. Ludwig, Maria B. Lebron, Anthony Pennello, Carmine Carpenito, Juqun Shen
Publikováno v:
Molecular Cancer Therapeutics. 19:988-998
The CD137 receptor plays a key role in mediating immune response by promoting T cell proliferation, survival, and memory. Effective agonism of CD137 has the potential to reinvigorate potent antitumor immunity either alone or in combination with other
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc94399303b472e397241fa6366ca08f
https://doi.org/10.1158/1535-7163.mct-19-0893
https://doi.org/10.1158/1535-7163.mct-19-0893
Autor:
David Surguladze, Dale L. Ludwig, Ying Wang, Gregory P. Donoho, Nina Zanella, Ruslan D. Novosiadly, Christopher B. Damoci, Malcolm A. Smith, Colleen A. Burns, James T. DeLigio, Marie Prewett, Heinz H. Fiebig, Michael Amatulli, Peter J. Houghton, Amelie Forest
Publikováno v:
Molecular Cancer Research. 13:1615-1626
Despite a recent shift away from anti–insulin-like growth factor I receptor (IGF-IR) therapy, this target has been identified as a key player in the resistance mechanisms to various conventional and targeted agents, emphasizing its value as a thera
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4b69b3f29f01f65c076e6f007937ac0
https://doi.org/10.1158/1541-7786.mcr-15-0279
https://doi.org/10.1158/1541-7786.mcr-15-0279
Autor:
Scott W. Eastman, Swee-Seong Wong, Michael Topper, Thompson N. Doman, David Schaer, Jason Manro, Amaladas Nelusha, Sau-Chi Betty Yan, Ruslan D. Novosiadly, Gerald Hall, Julie Stewart, Michael Kalos, Victoria L. Peek, Any T. Pappas, Bruce W. Konicek, Jennifer R. Stephens, Beverly L. Falcon, Philip W. Iversen, Richard A. Walgren, Um L. Um, Kelly M. Credille, Colleen A. Burns
Publikováno v:
Cancer Research. 77:5590-5590
The combination of tumor targeted therapeutics with PD-L1 checkpoint blockade is being explored as a method to increase the clinical benefits of immunotherapy, and expand response to additional cancer types. Merestinib (Mer) is a kinase inhibitor tar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::be254af902ace0bd3b087abf257fdef7
https://doi.org/10.1158/1538-7445.am2017-5590
https://doi.org/10.1158/1538-7445.am2017-5590
Autor:
Timothy Bailey, Nick Loizos, Jason E. Toombs, David E. Gerber, Jennifer Malaby, Colleen A. Burns, Michael Peyton, Rolf A. Brekken, Inga J Duignan, Michael T. Dellinger, Puja Gupta
Publikováno v:
Molecular Cancer Therapeutics. 11:2473-2482
In lung cancer, platelet-derived growth factor receptor α (PDGFRα) is expressed frequently by tumor-associated stromal cells and by cancer cells in a subset of tumors. We sought to determine the effect of targeting stromal PDGFRα in preclinical lu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a42ffbcb8964f2384bc84c79c499123
https://doi.org/10.1158/1535-7163.mct-12-0431
https://doi.org/10.1158/1535-7163.mct-12-0431
Publikováno v:
Active Learning in Higher Education. 13:191-201
The use of classroom capture systems (systems that capture audio and video footage of a lecture and attempt to replicate a classroom experience) is becoming increasingly popular at the university level. However, research on the effectiveness of class
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::335f0c9c98b12ccd05b705229c36b8b7
https://doi.org/10.1177/1469787412452982
https://doi.org/10.1177/1469787412452982
Autor:
Andrew J. Dropsey, Amelie Forest, William John Feaver, Colleen Burns Burns, Nick Loizos, Jennifer Gruber, Xuemei Guo, Armando R. Irizarry, Marie Prewett, Ruslan D. Novosiadly, Timothy R. Mack
Publikováno v:
Molecular Cancer Therapeutics. 14:C129-C129
While FGFR4 and its ligand FGF19 represent a promising target for cancers in which FGF19 is overexpressed or gene amplified, inhibition of this pathway carries a potential toxicity risk due to the role of FGFR4 in bile acid homeostasis. Treatment wit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9d18d5ae96b2321302e9996189507782
https://doi.org/10.1158/1535-7163.targ-15-c129
https://doi.org/10.1158/1535-7163.targ-15-c129
Publikováno v:
Science. 267:1491-1494
RNA encoding the B subunit of the alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) subtype of ionotropic glutamate receptor (GluR-B) undergoes a posttranscriptional modification in which a genomically encoded adenosine is represented a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c97073c9c3135db91dcf029403c2c3c
https://doi.org/10.1126/science.7878468
https://doi.org/10.1126/science.7878468
Publikováno v:
Optometry (St. Louis, Mo.). 76(5)
Background Leber's hereditary optic neuropathy (LHON) is a bilateral optic neuropathy of mitochondrial inheritance that produces significant painless, central vision loss and dyschromatopsia. LHON usually occurs in young males between the ages of 15
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1abeb6fdc03551b210afd731761e6e0a
https://pubmed.ncbi.nlm.nih.gov/15884420
https://pubmed.ncbi.nlm.nih.gov/15884420