Zobrazeno 1 - 10
of 130
pro vyhledávání: '"Colleen A McClung"'
Autor:
Madeline R Scott, Wei Zong, Kyle D Ketchesin, Marianne L Seney, George C Tseng, Bokai Zhu, Colleen A McClung
Publikováno v:
PLoS Biology, Vol 21, Iss 1, p e3001688 (2023)
Twelve-hour (12 h) ultradian rhythms are a well-known phenomenon in coastal marine organisms. While 12 h cycles are observed in human behavior and physiology, no study has measured 12 h rhythms in the human brain. Here, we identify 12 h rhythms in tr
Externí odkaz:
https://doaj.org/article/2d696377f12e4c7ea7023dba6e4fe7d5
Autor:
Yinghong Pan, Heather Ballance, Huan Meng, Naomi Gonzalez, Sam-Moon Kim, Leymaan Abdurehman, Brian York, Xi Chen, Yisrael Schnytzer, Oren Levy, Clifford C Dacso, Colleen A McClung, Bert W O'Malley, Silvia Liu, Bokai Zhu
Publikováno v:
PLoS Biology, Vol 18, Iss 1, p e3000580 (2020)
Our group recently characterized a cell-autonomous mammalian 12-h clock independent from the circadian clock, but its function and mechanism of regulation remain poorly understood. Here, we show that in mouse liver, transcriptional regulation signifi
Externí odkaz:
https://doaj.org/article/c2dd094cb87d4a129031aa33f2653b0a
Autor:
Angela Renee Ozburn, Kush ePurohit, Puja K Parekh, Gabrielle N Kaplan, Edgardo eFalcon, Shibani eMukherjee, Hannah M Cates, Colleen A McClung
Publikováno v:
Frontiers in Psychiatry, Vol 7 (2016)
Circadian rhythm disruptions are prominently associated with Bipolar Disorder (BD). Circadian rhythms are regulated by the molecular clock, a family of proteins that function together in a transcriptional-translational feedback loop. The CLOCK protei
Externí odkaz:
https://doaj.org/article/8d976a29193749af877455eb254ab54e
Autor:
Puja K Parekh, Colleen A McClung
Publikováno v:
Frontiers in Psychiatry, Vol 6 (2016)
Evidence from clinical and preclinical research provides an undeniable link between disruptions in the circadian clock and the development of psychiatric diseases including mood and substance abuse disorders. The molecular clock, which controls daily
Externí odkaz:
https://doaj.org/article/f58df25a2330499b9bb92c7aa1ed3452
Autor:
Michelle M Sidor, Colleen A Mcclung
Publikováno v:
Frontiers in Behavioral Neuroscience, Vol 8 (2014)
The ability to probe defined neural circuits with both the spatial and temporal resolution imparted by optogenetics has transformed the field of neuroscience. Although much attention has been paid to the advantages of manipulating neural activity at
Externí odkaz:
https://doaj.org/article/f552e18164204a25ac934e7d0aa60e36
Publikováno v:
PLoS ONE, Vol 8, Iss 6, p e66438 (2013)
Several studies have suggested that disruptions in circadian rhythms contribute to the pathophysiology of multiple psychiatric diseases, including drug addiction. In fact, a number of the genes involved in the regulation of circadian rhythms are also
Externí odkaz:
https://doaj.org/article/ee191efc6e1948529e4242b225b590e6
Autor:
Taylor A Stowe, Colleen A McClung
Publikováno v:
Clinical Interventions in Aging. 18:655-666
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::33f8d371183a0aff3d2b2cbf95c92dd5
https://doi.org/10.2147/cia.s380436
https://doi.org/10.2147/cia.s380436
Astrocyte Molecular Clock Function in the Nucleus Accumbens Is Important for Reward-Related Behavior
Autor:
Darius D. Becker-Krail, Kyle D. Ketchesin, Jennifer N. Burns, Wei Zong, Mariah A. Hildebrand, Lauren M. DePoy, Chelsea A. Vadnie, George C. Tseng, Ryan W. Logan, Yanhua H. Huang, Colleen A. McClung
Publikováno v:
Biol Psychiatry
BACKGROUND: Substance use disorders (SUDs) are associated with disruptions in circadian rhythms. Both human and animal work has shown the integral role for circadian clocks in the modulation of reward behaviors. Interestingly, astrocytes have emerged
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52fa48ae0094260e4fb29f3ec81c2ffd
https://doi.org/10.1016/j.biopsych.2022.02.007
https://doi.org/10.1016/j.biopsych.2022.02.007
Publikováno v:
Scientific Reports. 13
N-linked glycosylation is a critical post translational modification of eukaryotic proteins. N-linked glycans are present on surface and secreted filarial proteins that play a role in host parasite interactions. Examples of glycosylated Brugia malayi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e714a0146a6247e6ae4e8adff0b21adc
https://doi.org/10.1038/s41598-023-34936-9
https://doi.org/10.1038/s41598-023-34936-9
Autor:
Kyle D. Ketchesin, Panos Roussos, Colleen A. McClung, Gabriel E. Hoffman, Ryan W. Logan, George C. Tseng, Xiangning Xue, Marianne L. Seney
Publikováno v:
Biol Psychiatry
Background Diurnal rhythms in gene expression have been detected in the human brain. Previous studies found that males and females exhibit 24-hour rhythms in known circadian genes, with earlier peak expression in females. Whether there are sex differ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f6160140082a6c605d7be96d4093603
https://doi.org/10.1016/j.biopsych.2021.03.005
https://doi.org/10.1016/j.biopsych.2021.03.005