Zobrazeno 1 - 10
of 79
pro vyhledávání: '"Colleen, Shea"'
Autor:
David J. Szalda, Youwen Xu, Wenchao Qu, Michael J. Schueller, David Alexoff, Richard A. Ferrieri, Tassilo Gleede, Aylin Sibel Cankaya, Ruma Hoque, So Jeong Lee, Barbara Riehl, Lena Kersting, Colleen Shea, Joanna S. Fowler
Publikováno v:
Chemistry - A European Journal. 24:6848-6853
The development of a convenient and rapid method to synthesize radiolabeled, enantiomerically pure amino acids (AAs) as potential positron emission tomography (PET) imaging agents for mapping various biochemical transformations in living organisms re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::784184a6506984c4dcc6e0aa2fe970dc
https://doi.org/10.1002/chem.201801029
https://doi.org/10.1002/chem.201801029
Autor:
Youwen, Xu, Aylin Sibel, Cankaya, Ruma, Hoque, So Jeong, Lee, Colleen, Shea, Lena, Kersting, Michael, Schueller, Joanna S, Fowler, David, Szalda, David, Alexoff, Barbara, Riehl, Tassilo, Gleede, Richard A, Ferrieri, Wenchao, Qu
Publikováno v:
Chemistry (Weinheim an der Bergstrasse, Germany). 24(26)
The development of a convenient and rapid method to synthesize radiolabeled, enantiomerically pure amino acids (AAs) as potential positron emission tomography (PET) imaging agents for mapping various biochemical transformations in living organisms re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ebe92acc367ae658cbc5fe8921551404
https://pubmed.ncbi.nlm.nih.gov/29504637
https://pubmed.ncbi.nlm.nih.gov/29504637
Autor:
Sojeong Lee, Michael J. Schueller, David Alexoff, Dohyun Kim, Wenchao Qu, Joanna S. Fowler, Colleen Shea
Publikováno v:
Tetrahedron Letters. 56:517-520
An operationally friendly, two-step, one-pot process has been developed for the rapid synthesis of carbon-11 labeled indole-3-acetic acid ([11C]IAA or [11C]auxin). By replacing an aprotic polar solvent with tetraethylene glycol, nucleophilic [11C]cya
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad96ad9acfe37122fa9d0acbe983946e
https://doi.org/10.1016/j.tetlet.2014.12.014
https://doi.org/10.1016/j.tetlet.2014.12.014
Autor:
Lena Kersting, Tassilo Gleede, Wenchao Qu, Aylin Sibel Cankaya, Michael J. Schueller, David Alexoff, Colleen Shea, Joanna S. Fowler, Barbara Riehl
Publikováno v:
Amino Acids. 47:525-533
Carbon-11 (β+ emitter, t 1/2 = 20.4 min) radiolabeled l-glutamine is a potentially useful molecular imaging agent that can be utilized with positron emission tomography for both human oncological diagnosis and plant imaging research. Based upon a pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b23b70266f7e7874b390886c110eb117
https://doi.org/10.1007/s00726-014-1883-z
https://doi.org/10.1007/s00726-014-1883-z
Autor:
Stanley Fahn, Michelle Gilmor, Pauline Carter, Barbara Hubbard, David Alexoff, Payton King, Lisa Muench, Colleen Shea, Karen Apelskog-Torres, Elena Shumay, Millard Jayne, Fred McCall-Perez, Jean Logan, Frank Telang, Gene-Jack Wang, Nora D. Volkow, Joanna S. Fowler, Youwen Xu
Publikováno v:
Neuropsychopharmacology
Selegiline (L-deprenyl) is a selective, irreversible inhibitor of monoamine oxidase B (MAO-B) at the conventional dose (10 mg/day oral) that is used in the treatment of Parkinson's disease. However, controlled studies have demonstrated antidepressant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::795fa52021b720ae23c278ba6f790b7a
http://europepmc.org/articles/PMC4289953
http://europepmc.org/articles/PMC4289953
Autor:
Patrick J. Riss, Franklin I. Aigbirhio, Colleen Shea, Sung Won Kim, Valentina Ferrari, Donald Warner, Youwen Xu, Pauline Carter, Jacob M. Hooker, Frank Roesch, Joanna S. Fowler
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 22:679-682
N-(4-fluorobut-2-yn-1-yl)-2β-carbomethoxy-3β-(4′-tolyl)nortropane (PR04.MZ, 1) is a PET radioligand for the non-invasive exploration of the function of the cerebral dopamine transporter (DAT). A reliable automated process for routine production o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9b72f0db74fb159b85c736d6fbd5a405
https://doi.org/10.1016/j.bmcl.2011.10.053
https://doi.org/10.1016/j.bmcl.2011.10.053
Autor:
Colleen Shea, David Alexoff, Sung Won Kim, Payton King, Gene-Jack Wang, Pauline Carter, Youwen Xu, Millard Jayne, Barbara Hubbard, Jean Logan, David J. Schlyer, Deborah Pareto, Frank Telang, Lisa Muench, Joanna S. Fowler, Anat Biegon
Publikováno v:
Synapse. 64:801-807
Aromatase catalyzes the last step in estrogen biosynthesis. Brain aromatase is involved in diverse neurophysiological and behavioral functions including sexual behavior, aggression, cognition, and neuroprotection. Using positron emission tomography (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac231a88b1b9bb200673bfe97cc85b26
https://doi.org/10.1002/syn.20791
https://doi.org/10.1002/syn.20791
Publikováno v:
Journal of Medicinal Chemistry. 53:2882-2891
The front-line tuberculosis (TB) chemotherapeutics isoniazid (INH), rifampicin (RIF), and pyrazinamide (PZA) have been labeled with carbon-11 and the biodistribution of each labeled drug has been determined in baboons using positron emission tomograp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42855f9f09bcee9a12a0eb75ae4914f9
https://doi.org/10.1021/jm901858n
https://doi.org/10.1021/jm901858n
Autor:
Thomas A. Munro, Cécile Béguin, Jacob M. Hooker, David Alexoff, Colleen Shea, Youwen Xu, Bruce M. Cohen
Publikováno v:
Neuropharmacology. 57:386-391
Salvinorin A (SA) is a potent kappa opioid agonist with a brief duration of action. Consistent with this, our previous positron emission tomography (PET) studies of carbon-11 labeled SA showed that brain levels decrease rapidly after intravenous admi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f714ca2bb480dd22c01e7175aba6404
https://doi.org/10.1016/j.neuropharm.2009.06.044
https://doi.org/10.1016/j.neuropharm.2009.06.044
Autor:
Anat Biegon, Zachary E. Katsamanis, Lisa Muench, David Alexoff, Jacob M. Hooker, Carolin W. Ehrlich, Colleen Shea, Pauline Carter, Youwen Xu, Joanna S. Fowler, Payton King, Sung Won Kim
Publikováno v:
Nuclear Medicine and Biology. 36:323-334
Introduction We reinvestigated the synthesis of [ N -methyl- 11 C]vorozole, a radiotracer for aromatase, and discovered the presence of an N -methyl isomer which was not removed in the original purification method. Herein we report the preparation an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2cd84b20e80bcac4b75ebe156417450a
https://doi.org/10.1016/j.nucmedbio.2008.12.013
https://doi.org/10.1016/j.nucmedbio.2008.12.013