Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Colleen, Scheitrum"'
Autor:
Colleen Scheitrum, Catherine Rucker-Martin, Rodolphe Fischmeister, Patrick Donzeau-Gouge, Christoph Maack, Moses Xie, Marco Conti, Jérôme Leroy, Leif Hove-Madsen, Cristina E. Molina, Ignacio Verde, Wito Richter, Grégoire Vandecasteele, Illkyu-Oliver Lee, Anna Llach
Publikováno v:
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
instname
r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
instname
Objectives This study was designed to examine whether a cyclic adenosine monophosphate (cAMP) phosphodiesterase (PDE), PDE4, is expressed in human atrium and contributes to the control of electrical stability. Background Atrial fibrillation is accomp
Publikováno v:
Molecular Pharmacology. 80:281-293
In addition to xenobiotics and several other endogenous metabolites, multidrug-resistance proteins (MRPs) extrude the second-messenger cAMP from various cells. Pharmacological and/or genetic inactivation of MRPs has been shown to augment intracellula
Autor:
Marco Conti, Elise Blanchard, Moses Xie, Colleen Scheitrum, Tao Lei, Wito Richter, Brigitte E. Blackman, Delphine Mika
Publikováno v:
The Biochemical journal, vol 459, iss 3
PDE4s (type 4 cyclic nucleotide phosphodiesterases) are divided into long and short forms by the presence or absence of conserved N-terminal domains termed UCRs (upstream conserved regions). We have shown previously that PDE4D2, a short variant, is a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8701347d290e4e571977fcb9459bc9cf
https://escholarship.org/uc/item/4qr0k0vf
https://escholarship.org/uc/item/4qr0k0vf
Autor:
Walter E. Finkbeiner, Elise Blanchard, Marco Conti, Dieter C. Gruenert, Moses Xie, Colleen Scheitrum, Lorna Zlock, Alan S. Verkman, Anna Lao, Wan Namkung, Wito Richter, Delphine Mika
Publikováno v:
The FASEB Journal. 28
Cystic fibrosis (CF) is caused by mutations in the gene encoding the cystic fibrosis transmembrane conductance regulator (CFTR) that impair its expression or function. PKA phosphorylation is the ma...
Autor:
Wan Namkung, Walter E. Finkbeiner, Delphine Mika, Moses Xie, Dieter C. Gruenert, Marco Conti, Wito Richter, Alan S. Verkman, Anna Lao, Lorna Zlock, Elise Blanchard, Colleen Scheitrum
Cystic fibrosis (CF) is caused by mutations in the gene encoding the cystic fibrosis transmembrane conductance regulator (CFTR) that impair its expression and/or chloride channel function. Here, we provide evidence that type 4 cyclic nucleotide phosp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a6c3f5a7af5032a175b3cbfcb477a48
https://europepmc.org/articles/PMC3898646/
https://europepmc.org/articles/PMC3898646/
Autor:
Colleen Scheitrum, Wito Richter, Marco Conti, Philippe Mateo, Moses Xie, Delphine Mika, Florence Lefebvre, Flavien Charpentier, Julia Schittl, Rodolphe Fischmeister, Ruth E. Westenbroek, Jérôme Leroy, Grégoire Vandecasteele, Liliana R.V. Castro, Aniella Abi-Gerges, William A. Catterall
Publikováno v:
Journal of Clinical Investigation
Journal of Clinical Investigation, American Society for Clinical Investigation, 2011, 121 (7), pp.2651-2661. ⟨10.1172/JCI44747⟩
Journal of Clinical Investigation, American Society for Clinical Investigation, 2011, 121 (7), pp.2651-2661. ⟨10.1172/JCI44747⟩
β-Adrenergic receptors (β-ARs) enhance cardiac contractility by increasing cAMP levels and activating PKA. PKA increases Ca2+-induced Ca2+ release via phosphorylation of L-type Ca2+ channels (LTCCs) and ryanodine receptor 2. Multiple cyclic nucleot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6aac8285a825c5c166d1ec0ab76242fb
https://hal.archives-ouvertes.fr/hal-02940351/document
https://hal.archives-ouvertes.fr/hal-02940351/document
Publikováno v:
Richter, Wito; Xie, Moses; Scheitrum, Colleen; Krall, Judith; Movsesian, Matthew A.; & Conti, Marco. (2011). Conserved expression and functions of PDE4 in rodent and human heart. Basic Research in Cardiology, 106(2), pp 249-262. doi: 10.1007/s00395-010-0138-8. Retrieved from: http://www.escholarship.org/uc/item/75c430rd
Basic research in cardiology, vol 106, iss 2
Basic Research in Cardiology
Basic research in cardiology, vol 106, iss 2
Basic Research in Cardiology
PDE4 isoenzymes are critical in the control of cAMP signaling in rodent cardiac myocytes. Ablation of PDE4 affects multiple key players in excitation–contraction coupling and predisposes mice to the development of heart failure. As little is known
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e7335ba0006537f9a4ad0583c971bfb
http://www.escholarship.org/uc/item/75c430rd
http://www.escholarship.org/uc/item/75c430rd
Autor:
Jérôme, Leroy, Wito, Richter, Delphine, Mika, Liliana R V, Castro, Aniella, Abi-Gerges, Moses, Xie, Colleen, Scheitrum, Florence, Lefebvre, Julia, Schittl, Philippe, Mateo, Ruth, Westenbroek, William A, Catterall, Flavien, Charpentier, Marco, Conti, Rodolphe, Fischmeister, Grégoire, Vandecasteele
Publikováno v:
The Journal of clinical investigation. 121(7)
β-Adrenergic receptors (β-ARs) enhance cardiac contractility by increasing cAMP levels and activating PKA. PKA increases Ca2+-induced Ca2+ release via phosphorylation of L-type Ca2+ channels (LTCCs) and ryanodine receptor 2. Multiple cyclic nucleot