Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.

LGR5 expression is regulated by EGF in early colorectal adenomas and governs EGFR inhibitor sensitivity

Autor: Morgan, R G, Mortensson, E, Legge, D N, Gupta, B, Collard, T J, Greenhough, A, Williams, A C

Publikováno v: Morgan, R G, Mortensson, E, Legge, D N, Gupta, B, Collard, T J, Greenhough, A & Williams, A C 2018, ' LGR5 expression is regulated by EGF in early colorectal adenomas and governs EGFR inhibitor sensitivity ', British Journal of Cancer, vol. 118, no. 4, pp. 558-565 . https://doi.org/10.1038/bjc.2017.412
British Journal of Cancer

BACKGROUND: LGR5 serves as a co-receptor for Wnt/β-catenin signalling and marks normal intestinal stem cells; however, its role in colorectal cancer (CRC) remains controversial. LGR5(+) cells are known to exist outside the stem cell niche during CRC

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::8d1777b1c1ee9d2daa80034a055315bb
https://research-information.bris.ac.uk/en/publications/5da99d41-043c-4f19-b249-26ab9ddeef49

BAG-1 suppresses expression of the key regulatory cytokine transforming growth factor β (TGF-β1) in colorectal tumour cells.

Autor: Skeen, V R¹, Collard, T J¹, Southern, S L¹, Greenhough, A¹, Hague, A², Townsend, P A³, Paraskeva, C¹, Williams, A C¹

Publikováno v: Oncogene. 9/19/2013, Vol. 32 Issue 38, p4490-4499. 10p. 1 Diagram, 4 Graphs.

An acidic environment leads to p53 dependent induction of apoptosis in human adenoma and carcinoma cell lines: implications for clonal selection during colorectal carcinogenesis.

Autor: Williams, A C, Collard, T J, Paraskeva, C

Publikováno v: Oncogene. 5/27/99, Vol. 18 Issue 21, p3199. 6p.

Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.