Zobrazeno 1 - 10
of 102
pro vyhledávání: '"Collapsin response mediator protein-2"'
Autor:
Seiko Ikezu, Kaitlin L. Ingraham Dixie, Lacin Koro, Takashi Watanabe, Kozo Kaibuchi, Tsuneya Ikezu
Publikováno v:
Acta Neuropathologica Communications, Vol 8, Iss 1, Pp 1-16 (2020)
Abstract The accumulation of phosphorylated tau protein (pTau) in the entorhinal cortex (EC) is the earliest tau pathology in Alzheimer’s disease (AD). Tau tubulin kinase-1 (TTBK1) is a neuron-specific tau kinase and expressed in the EC and hippoca
Externí odkaz:
https://doaj.org/article/ef360e4e695c497c974acd6530808c60
Autor:
Jian-Nan Zhang, Jan C Koch
Publikováno v:
Neural Regeneration Research, Vol 12, Iss 5, Pp 692-695 (2017)
Axonal degeneration is a key pathological feature in many neurological diseases. It often leads to persistent deficits due to the inability of axons to regenerate in the central nervous system. Therefore therapeutic approaches should optimally both a
Externí odkaz:
https://doaj.org/article/b92492c0dd6a41b78e3e790e11d97c2b
Publikováno v:
Biomedicines, Vol 9, Iss 1, p 27 (2021)
Somatostatin is involved in the regulation of multiple signaling pathways and affords neuroprotection in response to neurotoxins. In the present study, we investigated the role of Somatostatin-14 (SST) in cell viability and the regulation of phosphor
Externí odkaz:
https://doaj.org/article/d7d90fbf570d45af8603cb8c70cb4c38
Publikováno v:
Chinese Medical Journal, Vol 128, Iss 7, Pp 919-927 (2015)
Background: Collapsin response mediator protein-2 (CRMP2), a multifunctional cytosolic protein highly expressed in the brain, is degraded by calpain following traumatic brain injury (TBI), possibly inhibiting posttraumatic neurite regeneration. Lipid
Externí odkaz:
https://doaj.org/article/6cebf4882b98454abacf724adabb5f9a
Autor:
Hiroshi Kohama, Haruka Hoshino, Hiroyuki Arai, Suresh Awale, Hironori Fujiwara, Kinzo Matsumoto, Dya Fita Dibwe, Yukitsuka Kudo, Jun Yoshida
Publikováno v:
Journal of Traditional and Complementary Medicine
Journal of Traditional and Complementary Medicine, Vol 9, Iss 4, Pp 328-335 (2019)
Journal of Traditional and Complementary Medicine, Vol 9, Iss 4, Pp 328-335 (2019)
Background and aim The aging-dependent activation of glycogen synthase kinase-3β (GSK-3β) has been suggested to be important in the onset of dementia. To discover novel therapeutic Kampo medicines for dementia, we examined the effects of orengedoku
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6d92c1db3b8d93c60ea41118d909c28
http://europepmc.org/articles/PMC6702137
http://europepmc.org/articles/PMC6702137
Autor:
Joseph T. Coyle, Richard L. Sidman, Brian T. D. Tobe, Aoi Jitsuki-Takahashi, Hiroko Makihara, Fumio Nakamura, Haruko Nakamura, Yoshio Hirayasu, Keisuke Watanabe, Naoya Yamashita, Glenn T. Konopaske, Evan Y. Snyder, Cameron D Pernia, Yoshio Goshima, Munetaka Nomoto, Reina Aoki, Yusuke Saigusa, Toshihiko Baba, Francine M. Benes, Mari Saito
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance There are no biomarkers for schizophrenia (SCZ), a disorder of dysfunctional neural networks. We demonstrate that a master regulator of cytoskeleton (“CRMP2”) and, hence, neural circuitry, may form the basis for such a biomarker beca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5a9bb79a052ee84bd9c78fb40d942ed
http://europepmc.org/articles/PMC8346854
http://europepmc.org/articles/PMC8346854
Publikováno v:
Biomedicines
Volume 9
Issue 1
Biomedicines, Vol 9, Iss 27, p 27 (2021)
Volume 9
Issue 1
Biomedicines, Vol 9, Iss 27, p 27 (2021)
Somatostatin is involved in the regulation of multiple signaling pathways and affords neuroprotection in response to neurotoxins. In the present study, we investigated the role of Somatostatin-14 (SST) in cell viability and the regulation of phosphor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75738fdcf1a3094a82aea4d699001792
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Autor:
Sergey Kalinin, Kathy Kowal, Natalia Marangoni, Douglas L. Feinstein, Kinga Lis, Kenneth Hensley, Jeffrey L. Dupree, Lucia Lisi, Rajesh Khanna, Shao Xia Lin, Aubin Moutal
Publikováno v:
ASN Neuro, Vol 11 (2019)
ASN NEURO
ASN NEURO
We previously showed that treatment with lanthionine ketimine ethyl ester (LKE) reduced disease severity and axonal damage in an experimental autoimmune encephalomyelitis (EAE) mouse model of multiple sclerosis and increased neuronal maturation and s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dae4b56d3c1fe7d993b3c4bca27c7859
https://doaj.org/article/edd02eb328f24478881a1a8638ea6b9e
https://doaj.org/article/edd02eb328f24478881a1a8638ea6b9e