Thrombospondin 1 missense alleles induce extracellular matrix protein aggregation and TM dysfunction in congenital glaucoma.

Autor: Fu H; Vascular Biology Program, Department of Surgery, Boston Children's Hospital, Boston, Massachusetts, USA.; Department of Ophthalmology, Harvard Medical School, Boston, Massachusetts, USA., Siggs OM; Department of Ophthalmology, Flinders University, Adelaide, South Australia, Australia.; Garvan Institute of Medical Research, Darlinghurst, New South Wales, Australia., Knight LS; Department of Ophthalmology, Flinders University, Adelaide, South Australia, Australia., Staffieri SE; Centre for Eye Research Australia (CERA), Royal Victorian Eye and Ear Hospital, East Melbourne, Victoria, Australia.; Department of Ophthalmology, University of Melbourne, Department of Surgery, Parkville, Victoria, Australia.; Department of Ophthalmology, Royal Children's Hospital, Parkville, Victoria, Australia., Ruddle JB; Department of Ophthalmology, Royal Children's Hospital, Parkville, Victoria, Australia., Birsner AE; Vascular Biology Program, Department of Surgery, Boston Children's Hospital, Boston, Massachusetts, USA., Collantes ER; Department of Ophthalmology, Harvard Medical School, Boston, Massachusetts, USA., Craig JE; Department of Ophthalmology, Flinders University, Adelaide, South Australia, Australia., Wiggs JL; Department of Ophthalmology, Harvard Medical School, Boston, Massachusetts, USA.; Department of Ophthalmology, Massachusetts Eye and Ear, Boston, Massachusetts, USA.; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Boston, Massachusetts, USA., D'Amato RJ; Vascular Biology Program, Department of Surgery, Boston Children's Hospital, Boston, Massachusetts, USA.; Department of Ophthalmology, Harvard Medical School, Boston, Massachusetts, USA.

Publikováno v: The Journal of clinical investigation [J Clin Invest] 2022 Dec 01; Vol. 132 (23). Date of Electronic Publication: 2022 Dec 01.

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Three-dimensional quantitative structure-activity relationship study of the cannabimimetic (aminoalkyl)indoles using comparative molecular field analysis.

Autor: Shim JY; Sanofi Research Division, Sanofi-Winthrop, Collegeville, Pennsylvania 19426, USA., Collantes ER, Welsh WJ, Subramaniam B, Howlett AC, Eissenstat MA, Ward SJ

Publikováno v: Journal of medicinal chemistry [J Med Chem] 1998 Nov 05; Vol. 41 (23), pp. 4521-32.

Application of a pruning algorithm to optimize artificial neural networks for pharmaceutical fingerprinting.

Autor: Tetko IV; Department of Biomedical Applications, Institute of Bioorganic and Petroleum Chemistry, Kiev, Ukraine., Villa AE, Aksenova TI, Zielinski WL, Brower J, Collantes ER, Welsh WJ

Publikováno v: Journal of chemical information and computer sciences [J Chem Inf Comput Sci] 1998 Jul-Aug; Vol. 38 (4), pp. 660-8.

Preprocessing of HPLC trace impurity patterns by wavelet packets for pharmaceutical fingerprinting using artificial neural networks.

Autor: Collantes ER; Department of Chemistry, University of Missouri-St. Louis 63121, USA., Duta R, Welsh WJ, Zielinski WL, Brower J

Publikováno v: Analytical chemistry [Anal Chem] 1997 Apr 01; Vol. 69 (7), pp. 1392-7.