Zobrazeno 1 - 10
of 792
pro vyhledávání: '"Collagen helix"'
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Publikováno v:
Egyptian Rheumatologist, Vol 44, Iss 1, Pp 11-14 (2022)
Aim of the work: To assess serum collagen triple helix repeat containing 1 (CTHRC1) protein level in rheumatoid arthritis (RA) patients and compare it with healthy controls. In addition, to evaluate the relation of its level with RA activity and seve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98bdde4921f5b2f3577854258656183c
https://doi.org/10.1016/j.ejr.2021.07.003
https://doi.org/10.1016/j.ejr.2021.07.003
Publikováno v:
Acta Biochimica et Biophysica Sinica. 53:805-814
Collagen is the main component of the extracellular matrix. Hydroxylation of proline residues on collagen, catalyzed by collagen prolyl 4-hydroxylase (C-P4H), is essential for the stability of the collagen triple helix. Vertebrate C-P4H is an α2β2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f0efe22b86e02f59e6706f4063c36961
https://doi.org/10.1093/abbs/gmab065
https://doi.org/10.1093/abbs/gmab065
Autor:
Anis Hanna, Linda Alex, Prasanth Balasubramanian, Arti V. Shinde, Ruoshui Li, Nikolaos G. Frangogiannis, Claudio Humeres
Publikováno v:
Matrix Biol
Tissue injury results in profound alterations in the collagen network, associated with unfolding of the collagen triple helix, proteolytic degradation and generation of fragments. In the infarcted myocardium, changes in the collagen network are criti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76c818efb007e04cebffa0bc96a9a1fa
https://doi.org/10.1016/j.matbio.2021.05.005
https://doi.org/10.1016/j.matbio.2021.05.005
Publikováno v:
Biomacromolecules. 22:2137-2147
There is a noted lack of understood, controllable interactions for directing the organization of collagen triple helices. While the field has had success using charge-pair interactions and cation-π interactions in helix design, these alone are not a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91ae249ae7754037023c2e1ad119b5c1
https://doi.org/10.1021/acs.biomac.1c00234
https://doi.org/10.1021/acs.biomac.1c00234
Autor:
I-Che Li, Jeffrey D. Hartgerink, Sarah A. H. Hulgan, Douglas R. Walker, Kevin J. Gonzalez, Caroline M. Peterson
Publikováno v:
Nature Chemistry. 13:260-269
Robust methods for predicting thermal stabilities of collagen triple helices are critical for understanding natural structure and stability in the collagen family of proteins and also for designing synthetic peptides mimicking these essential protein
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::49553797e82d46a15cdeeace8eabc939
https://doi.org/10.1038/s41557-020-00626-6
https://doi.org/10.1038/s41557-020-00626-6
Autor:
Szu-Huan Wang, Yi-Ting Sun, Chen-Hsu Yu, Yan-Chen Chen, Shu-Chuan Jao, Wei-Ming Wang, Ting-Hsuan Chen, Richard P. Cheng, Jing-Yuan Chang
Publikováno v:
Organic & Biomolecular Chemistry. 19:1860-1866
Collagen is a major structural component of the extracellular matrix and connective tissue. The key structural feature of collagen is the collagen triple helix, with a Xaa-Yaa-Gly (glycine) repeating pattern. The most frequently occurring triplet is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a920f08e687b9a5235908e6075480433
https://doi.org/10.1039/d0ob02190c
https://doi.org/10.1039/d0ob02190c
Autor:
Xabier Martinez de Morentin, Núria Planell, Juan P. Romero, Ming Wu, Paula García-Olloqui, Erika Lorenzo-Vivas, Stefan Janssens, David Gomez-Cabrero, Patxi San Martin-Uriz, Felipe Prosper, Gorka Bastarrika, David Lara-Astiaso, Miren Lasaga, Volkhard Lindner, Laura Castro-Labrador, Beatriz Pelacho, E. Iglesias, Igor Prudovsky, Sergey Ryzhov, Adrián Ruiz-Villalba, Diego Alignani, Yong-Ri Jin, Nikolaus Fortelny, Gema Medal, Amaia Vilas-Zornoza, Haifeng Yin, Silvia C. Hernandez, Juan José Gavira, Christoph Bock, Gloria Abizanda, Marcel Palacio
Publikováno v:
Circulation
Background: Cardiac fibroblasts (CFs) have a central role in the ventricular remodeling process associated with different types of fibrosis. Recent studies have shown that fibroblasts do not respond homogeneously to heart injury. Because of the limit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77d302f8dd59aca9c67e94d970efc18e
https://doi.org/10.1161/circulationaha.119.044557
https://doi.org/10.1161/circulationaha.119.044557
Autor:
Szymon W. Manka, Keith Brew
Publikováno v:
Journal of Molecular Biology. 432:5985-5993
Local unwinding of the collagen triple helix is a necessary step for initiating the collagen degradation cascade in extracellular matrices. A few matrix metalloproteinases (MMPs) are known to support this key process, but its energetic aspects remain
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1acb3e5ce95b621df45e02ce3893648d
https://doi.org/10.1016/j.jmb.2020.10.003
https://doi.org/10.1016/j.jmb.2020.10.003
Autor:
Ute Kolb, Galina Matveeva, Sebastian Bette, Jörg Stelzner, Thomas Schleid, Robert E. Dinnebier, Gerhard Eggert
Publikováno v:
Angewandte Chemie (International Ed. in English)
Helical motifs are common in nature, for example, the DNA double or the collagen triple helix. In the latter proteins, the helical motif originates from glycine, the smallest amino acid, whose molecular confirmation is closely related to acetic acid.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ce1a1e2a5d453efdca4b06675b3c3f2
http://europepmc.org/articles/PMC7318632
http://europepmc.org/articles/PMC7318632