Zobrazeno 1 - 10
of 2 520
pro vyhledávání: '"Collagen I"'
Publikováno v:
Respiratory Research, Vol 25, Iss 1, Pp 1-14 (2024)
Abstract Background The transformation of airway smooth muscle cells (ASMCs) from a quiescent phenotype to a hypersecretory and hypercontractile phenotype is a defining feature of asthmatic airway remodeling. Fisetin, a flavonoid compound, possesses
Externí odkaz:
https://doaj.org/article/5abd33add46e4a38bedaa07a803b6642
Publikováno v:
Iranian Journal of Basic Medical Sciences, Vol 27, Iss 7, Pp 832-840 (2024)
Objective(s): Slit guidance ligand 3 (SLIT3) has been identified as a potential therapeutic regulator against fibroblast activity and fibrillary collagen production in an autocrine manner. However, this research aims to investigate the potential role
Externí odkaz:
https://doaj.org/article/532d63f25b054662b67196e1964d033d
Publikováno v:
陆军军医大学学报, Vol 46, Iss 2, Pp 147-154 (2024)
Objective To investigate the effects of silencing connective tissue growth factor (CTGF) gene on growth, apoptosis, and expression of proliferating cell nuclear antigen (PCNA), CTGF, integrin alpha 5 (Itgα5) and collagen Ⅰ (ColⅠ) in rat hepatic
Externí odkaz:
https://doaj.org/article/18912323c71c43fe88ef64bafa334a8c
Autor:
Tri Hastono Setyo Hadi, Gatut Hardianto, Eighty Mardiyan Kurniawati, Harry Parathon, Ira Sari Yudaniayanti, Budi Utomo, Budi Iman Santoso
Publikováno v:
Clinical and Experimental Obstetrics & Gynecology, Vol 51, Iss 10, p 217 (2024)
Background: Vulvovaginal atrophy is part of the genitourinary syndrome of menopause caused by hypoestrogenic changes. This pathophysiological mechanism alters the concentration of collagen and elastin, which modifies the vaginal mucosa and impairs th
Externí odkaz:
https://doaj.org/article/c05f3cfd570a45329ce25af6c6bad238
Autor:
Tumisang Edward Maseko, Eva Peterová, Moustafa Elkalaf, Darja Koutová, Jan Melek, Pavla Staňková, Veronika Špalková, Reem Matar, Halka Lotková, Zuzana Červinková, Otto Kučera
Publikováno v:
Biomolecules, Vol 14, Iss 9, p 1179 (2024)
Various strategies have been employed to improve the reliability of 2D, 3D, and co-culture in vitro models of nonalcoholic fatty liver disease, including using extracellular matrix proteins such as collagen I to promote cell adhesion. While studies h
Externí odkaz:
https://doaj.org/article/f49d5b3112a34a999a8e994a2eb89568
Autor:
Rasha Zuhair Jasim
Publikováno v:
Iraqi Journal of Pharmaceutical Sciences, Vol 33, Iss 1 (2024)
Meningiomas are the most common primary intracellular slow growing benign tumor that are mostly arisen from meningeothelial (arachnoid) cells which surround the brain and the spinal cord. The aim of the present study is to innovate a biochemical rela
Externí odkaz:
https://doaj.org/article/33e5ea28332b41dab3ed71830b24ed3d
Autor:
Giulia Chiabotto, Armina Semnani, Elena Ceccotti, Marco Guenza, Giovanni Camussi, Stefania Bruno
Publikováno v:
Biomedicines, Vol 12, Iss 8, p 1849 (2024)
Hepatic fibrosis, arising from prolonged liver injury, entails the activation of hepatic stellate cells (HSCs) into myofibroblast-like cells expressing alpha-smooth muscle actin (α-SMA), thereby driving extracellular matrix deposition and fibrosis p
Externí odkaz:
https://doaj.org/article/77f071d6eb624638965807692843a3b1
Autor:
Serena Artone, Alessia Ciafarone, Francesca Rosaria Augello, Francesca Lombardi, Maria Grazia Cifone, Paola Palumbo, Benedetta Cinque, Giovanni Latella
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 16, p 8862 (2024)
The mechanism underlying intestinal fibrosis, the main complication of inflammatory bowel disease (IBD), is not yet fully understood, and there is no therapy to prevent or reverse fibrosis. We evaluated, in in vitro cellular models, the ability of di
Externí odkaz:
https://doaj.org/article/a39678790f0e4b44bbefb0e9f8b98615
Publikováno v:
Gels, Vol 10, Iss 7, p 450 (2024)
Cell–cell interactions between fibroblasts and immune cells, like macrophages, are influenced by interaction with the surrounding extracellular matrix during wound healing. In vitro hydrogel models that mimic and modulate these interactions, especi
Externí odkaz:
https://doaj.org/article/b7df87ed67de4fb0b3ccae193ac7783a