Zobrazeno 1 - 1
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pro vyhledávání: '"Colitis/physiopathology"'
Autor:
Subrata Ghosh, Yan Li, Victor Lam, Simon A. Hirota, Ramnik J. Xavier, Kelvin Ng, Daniel A. Muruve, Paul L. Beck, Mireille S. Potentier, Sean P. Colgan, Jeffrey Ng, Ken Kuljit S. Parhar, Donna-Marie McCafferty, Kevin P. Rioux, Jürg Tschopp, Misha Bawa, Justin A. MacDonald, Maitham A. Khajah, Alan Lueng
Publikováno v:
Inflammatory Bowel Diseases, vol. 17, no. 6, pp. 1359-1372
BACKGROUND:: Attenuated innate immune responses to the intestinal microbiota have been linked to the pathogenesis of Crohn's disease (CD). Recent genetic studies have revealed that hypofunctional mutations of NLRP3, a member of the NOD-like receptor