Zobrazeno 1 - 10
of 135
pro vyhledávání: '"Colin Thorpe"'
Autor:
Catherine S. Millar‐Haskell, John L. Sperduto, John H. Slater, Colin Thorpe, Jason P. Gleghorn
Publikováno v:
Journal of Extracellular Biology, Vol 1, Iss 7, Pp n/a-n/a (2022)
Abstract Quiescin sulfhydryl oxidase 1 (QSOX1) is a disulphide bond generating catalyst that is overexpressed in solid tumours. Expression of QSOX1 is linked to cancer cell invasion, tumour grade, and aberrant extracellular matrix (ECM) protein depos
Externí odkaz:
https://doaj.org/article/0a5fb959be3643e099e9398cea044c30
Autor:
Vamsi K Kodali, Shawn A Gannon, Sivakumar Paramasivam, Sonali Raje, Tatyana Polenova, Colin Thorpe
Publikováno v:
PLoS ONE, Vol 6, Iss 3, p e18187 (2011)
Under the shell of a chicken egg are two opposed proteinaceous disulfide-rich membranes. They are fabricated in the avian oviduct using fibers formed from proteins that are extensively coupled by irreversible lysine-derived crosslinks. The intractabi
Externí odkaz:
https://doaj.org/article/71e728db77af43bf8042972158707aa5
Pancreatic ductal adenocarcinoma (PDAC) is the 4th leading cause of cancer-related deaths in the U.S., despite only being the 11th most common cancer. The high mortality rates of PDAC can be partially attributed to the tumor microenvironment. Unlike
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::393d56d592b4a1ed928620130e793960
https://doi.org/10.1101/2022.10.19.512796
https://doi.org/10.1101/2022.10.19.512796
Autor:
Luke D. Lavis, Joseph M. Fox, William S. Trout, He Zhang, Julia E. Rosenberger, Xiaoyu Zou, Jonathan B. Grimm, Raghu Vannam, Hui Wang, Chuanqi Wang, Zibo Li, Xinqiao Jia, Tao Zhang, Colin Thorpe
Publikováno v:
J Am Chem Soc
Chromophores that absorb in the tissue-penetrant far-red/near-infrared window have long served as photocatalysts to generate singlet oxygen for photodynamic therapy. However, the cytotoxicity and side reactions associated with singlet oxygen sensitiz
Publikováno v:
Protein Science. 27:1509-1517
Gaussia princeps luciferase (GLuc) generates an intense burst of blue light when exposed to coelenterazine in the absence of ATP. Here we show that this 5-disulfide containing enzyme can be used as a facile and convenient substrate for studies of oxi
Publikováno v:
Biochemistry. 57:1178-1189
The development of genetically encoded fluorescent probes for analyte-specific imaging has revolutionized our understanding of intracellular processes. Current classes of intracellular probes depend on the selection of binding domains that either und
Autor:
Colin Thorpe, Leslie B. Poole
Publikováno v:
Protein Science. 28:5-7
Autor:
Samuel L. Scinto, Joseph M. Fox, Han Zhang, Nikifar Lazouski, Colin Thorpe, Shuang Liu, Xinqiao Jia, Gabriel A. Andrade, Joel Rosenthal, Yi Li, William S. Trout, Devin A. Hudson, Kevin T. Dicker
Publikováno v:
Journal of the American Chemical Society. 138:5978-5983
Rapid bioorthogonal reactivity can be induced by controllable, catalytic stimuli using air as the oxidant. Methylene blue (4 μM) irradiated with red light (660 nm) catalyzes the rapid oxidation of a dihydrotetrazine to a tetrazine thereby turning on
Autor:
Leslie B, Poole, Colin, Thorpe
Publikováno v:
Protein science : a publication of the Protein Society. 28(1)
Publikováno v:
Protein science : a publication of the Protein Society. 27(8)
Gaussia princeps luciferase (GLuc) generates an intense burst of blue light when exposed to coelenterazine in the absence of ATP. Here we show that this 5‐disulfide containing enzyme can be used as a facile and convenient substrate for studies of o