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pro vyhledávání: '"Colin T. Konishi"'
Autor:
Michael N. Wosczyna, Colin T. Konishi, Edgar E. Perez Carbajal, Theodore T. Wang, Rachel A. Walsh, Qiang Gan, Mark W. Wagner, Thomas A. Rando
Publikováno v:
Cell Reports, Vol 27, Iss 7, Pp 2029-2035.e5 (2019)
Summary: The necessity of mesenchymal stromal cells, called fibroadipogenic progenitors (FAPs), in skeletal muscle regeneration and maintenance remains unestablished. We report the generation of a PDGFRαCreER knockin mouse model that provides a spec
Externí odkaz:
https://doaj.org/article/c5bdd501a332466aa91295927507ab32
Autor:
Colin T. Konishi, Chengzu Long
Publikováno v:
Journal of Biomedical Research
There are an estimated 10 000 monogenic diseases affecting tens of millions of individuals worldwide. The application of CRISPR/Cas genome editing tools to treat monogenic diseases is an emerging strategy with the potential to generate personalized t
Autor:
Mark W. Wagner, Michael N. Wosczyna, Edgar E. Perez Carbajal, Thomas A. Rando, Colin T. Konishi, Theodore T. Wang, Qiang Gan, Ling Liu, Silvana Paredes, Christapher S. Morrissey, Rachel A. Walsh
Publikováno v:
Cell Stem Cell
Summary Intramuscular fatty deposits, which are seen in muscular dystrophies and with aging, negatively affect muscle function. The cells of origin of adipocytes constituting these fatty deposits are mesenchymal stromal cells, fibroadipogenic progeni
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bfb0e019d73e7fda8f5e0dbbc0c0a792
https://europepmc.org/articles/PMC8254802/
https://europepmc.org/articles/PMC8254802/
Autor:
Colin T. Konishi, Edgar E. Perez Carbajal, Qiang Gan, Theodore T. Wang, Mark W. Wagner, Michael N. Wosczyna, Thomas A. Rando, Rachel A. Walsh
Publikováno v:
Cell Reports, Vol 27, Iss 7, Pp 2029-2035.e5 (2019)
Summary: The necessity of mesenchymal stromal cells, called fibroadipogenic progenitors (FAPs), in skeletal muscle regeneration and maintenance remains unestablished. We report the generation of a PDGFRαCreER knockin mouse model that provides a spec
Autor:
Mohamed A.E. Ali, Sohini Chakraborty, Joseph Shin, Harold Elias, Isabel Beerman, Colin T. Konishi, Christopher Y. Park, Igor Dolgalev, Caryn J. Ha
Publikováno v:
Blood. 134:2479-2479
Aging hematopoiesis is characterized by increased numbers of immunophenotypic HSCs that exhibit impaired self-renewal and long-term reconstitution potential, both in competitive and noncompetitive settings. We previously demonstrated that normal youn