Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Colin T King"'
Autor:
Maria Pino, Susan Pereira Ribeiro, Amélie Pagliuzza, Khader Ghneim, Anum Khan, Emily Ryan, Justin L Harper, Colin T King, Sarah Welbourn, Luca Micci, Sol Aldrete, Keith A Delman, Theron Stuart, Michael Lowe, Jason M Brenchley, Cynthia A Derdeyn, Kirk Easley, Rafick P Sekaly, Nicolas Chomont, Mirko Paiardini, Vincent C Marconi
Publikováno v:
PLoS Pathogens, Vol 17, Iss 8, p e1009825 (2021)
Clinical outcomes are inferior for individuals with HIV having suboptimal CD4 T-cell recovery during antiretroviral therapy (ART). We investigated if the levels of infection and the response to homeostatic cytokines of CD4 T-cell subsets contributed
Externí odkaz:
https://doaj.org/article/067e37f438b34fd7827433be61b176ba
Autor:
Maria Pino, Sara Paganini, Claire Deleage, Kartika Padhan, Justin L Harper, Colin T King, Luca Micci, Barbara Cervasi, Joseph C Mudd, Kiran P Gill, Sherrie M Jean, Kirk Easley, Guido Silvestri, Jacob D Estes, Constantinos Petrovas, Michael M Lederman, Mirko Paiardini
Publikováno v:
PLoS Pathogens, Vol 15, Iss 10, p e1008081 (2019)
Lymph nodes (LN) and their resident T follicular helper CD4+ T cells (Tfh) are a critical site for HIV replication and persistence. Therefore, optimizing antiviral activity in lymphoid tissues will be needed to reduce or eliminate the HIV reservoir.
Externí odkaz:
https://doaj.org/article/317b112ab6a540088ba22b5560bb1102
Autor:
Maria Pino, Amélie Pagliuzza, M. Betina Pampena, Claire Deleage, Elise G. Viox, Kevin Nguyen, Inbo Shim, Adam Zhang, Justin L. Harper, Sadia Samer, Colin T. King, Barbara Cervasi, Kiran P. Gill, Stephanie Ehnert, Sherrie M. Jean, Michael L. Freeman, Jeffrey D. Lifson, Deanna Kulpa, Michael R. Betts, Nicolas Chomont, Michael M. Lederman, Mirko Paiardini
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-12 (2022)
Although antiretroviral therapy (ART) is able to successfully suppress plasma viremia in most people living with HIV, ART withdrawal typically results in viral replication and rebound. Authors investigate the effect, in terms of delay in viral replic
Externí odkaz:
https://doaj.org/article/02897c95d48247e0867184e05e8cc7b9
Autor:
Christina Mallarino-Haeger, Maria Pino, Elise G. Viox, Amélie Pagliuzza, Colin T. King, Kevin Nguyen, Justin L. Harper, Sol del Mar Aldrete, Barbara Cervasi, Keith A. Delman, Michael C. Lowe, Nicolas Chomont, Vincent C. Marconi, Mirko Paiardini
Publikováno v:
Journal of Virology. 97
This study provides new insights into the contributions of different CD4 + and CD8 + T-cell subsets to the anatomic differences between LN and blood in individuals with HIV who have optimal versus suboptimal CD4 + T-cell recovery. To our knowledge, t
Autor:
Jenna Read, Colin T. King, Maria Pino, Mirko Paiardini, Heather Amrine-Madsen, Michael Nekorchuk, Chi Ngai Chan, Cristin M. Galardi, Hong Wang, James Schawalder, Katharine J. Bar, A. Alicia Koblansky, Colleen S. McGary, Kevin Nguyen, Jacob D. Estes, Sherrie Jean, Samuel L. M. Raines, Shane D. Falcinelli, Jeffrey D. Lifson, Shari Gordon, Luca Micci, Guido Silvestri, Andrew Sanderson, Justin L. Harper, Brian Johns, David Favre, Emily Lindemuth, Kathleen Busman-Sahay, Barbara Cervasi, David M. Margolis
Publikováno v:
Nature Medicine. 26:519-528
The primary human immunodeficiency virus (HIV) reservoir is composed of resting memory CD4+ T cells, which often express the immune checkpoint receptors programmed cell death protein 1 (PD-1) and cytotoxic T lymphocyte-associated protein 4 (CTLA-4),
Autor:
Theron Stuart, Susan Pereira Ribeiro, Nicolas Chomont, Emily S. Ryan, Vincent C. Marconi, Justin L. Harper, Amélie Pagliuzza, Rafick Pierre Sekaly, Cynthia A. Derdeyn, Sol del Mar Aldrete, Luca Micci, Sarah Welbourn, Jason M. Brenchley, Keith A. Delman, Mirko Paiardini, Kirk Easley, Maria Pino, Anum Khan, Michael C. Lowe, Khader Ghneim, Colin T. King
Publikováno v:
PLoS Pathogens
PLoS Pathogens, Vol 17, Iss 8, p e1009825 (2021)
PLoS Pathogens, Vol 17, Iss 8, p e1009825 (2021)
Clinical outcomes are inferior for individuals with HIV having suboptimal CD4 T-cell recovery during antiretroviral therapy (ART). We investigated if the levels of infection and the response to homeostatic cytokines of CD4 T-cell subsets contributed
Autor:
Steven E. Bosinger, Jeffrey D. Lifson, Kirk Easley, Francois Villinger, Hong Wang, Philippe Rascle, Luca Micci, Guido Silvestri, Neeta Shenvi, Gregory K. Tharp, Nicolas Huot, Cristin M. Galardi, Colin T. King, Michaela Müller-Trutwin, Justin L. Harper, Amit A. Upadhyay, Beatrice Jacquelin, Mirko Paiardini
Publikováno v:
Nature Communications
Nature Communications, Nature Publishing Group, 2021, 12 (1), pp.2866. ⟨10.1038/s41467-021-23189-7⟩
Nature Communications, 2021, 12 (1), pp.2866. ⟨10.1038/s41467-021-23189-7⟩
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
Nature Communications, Nature Publishing Group, 2021, 12 (1), pp.2866. ⟨10.1038/s41467-021-23189-7⟩
Nature Communications, 2021, 12 (1), pp.2866. ⟨10.1038/s41467-021-23189-7⟩
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
Unlike HIV infection, which progresses to AIDS absent suppressive anti-retroviral therapy, nonpathogenic infections in natural hosts, such African green monkeys, are characterized by a lack of gut microbial translocation and robust secondary lymphoid
Autor:
Colin T. King, Constantinos Petrovas, Justin L. Harper, Maria Pino, Sherrie Jean, Kirk A. Easley, Sara Paganini, Joseph C. Mudd, Mirko Paiardini, Luca Micci, Jacob D. Estes, Guido Silvestri, Michael M. Lederman, Claire Deleage, Barbara Cervasi, Kartika Padhan, Kiran Gill
Publikováno v:
PLoS Pathogens
PLoS Pathogens, Vol 15, Iss 10, p e1008081 (2019)
PLoS Pathogens, Vol 15, Iss 10, p e1008081 (2019)
Lymph nodes (LN) and their resident T follicular helper CD4+ T cells (Tfh) are a critical site for HIV replication and persistence. Therefore, optimizing antiviral activity in lymphoid tissues will be needed to reduce or eliminate the HIV reservoir.
Autor:
Barbara Cervasi, Maria Pino, Colin T. King, Timothy N. Hoang, Julia Bergild McBrien, Hong Wang, Mirko Paiardini, Colleen S. McGary, Justin L. Harper, Luca Micci, Guido Silvestri
Publikováno v:
Journal of Virology. 93
The bone marrow (BM) is the key anatomic site for hematopoiesis and plays a significant role in the homeostasis of mature T cells. However, very little is known on the phenotype of BM-derived CD4+ T cells, their fate during simian immunodeficiency vi
Autor:
Timothy N, Hoang, Justin L, Harper, Maria, Pino, Hong, Wang, Luca, Micci, Colin T, King, Colleen S, McGary, Julia B, McBrien, Barbara, Cervasi, Guido, Silvestri, Mirko, Paiardini
Publikováno v:
Journal of virology. 93(1)
The bone marrow (BM) is the key anatomic site for hematopoiesis and plays a significant role in the homeostasis of mature T cells. However, very little is known on the phenotype of BM-derived CD4(+) T cells, their fate during simian immunodeficiency