Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Colin S, Burns"'
Publikováno v:
Oncotarget
Metastatic melanoma is the most deadly skin neoplasm in the United States. Outcomes for this lethal disease have improved dramatically due to the use of both targeted and immunostimulatory drugs. Immunogenic cell death (ICD) has emerged as another ap
Autor:
Daniel A. Ladin, Ahmed E. M. Elhassanny, Rukiyah Van Dross, Kathleen Thayne, Andrew J. Morris, Colin S. Burns, Robert A. Kobet, Allison S. Danell, Hussam Albassam, Eman Soliman
Publikováno v:
Prostaglandins & Other Lipid Mediators. 142:9-23
The combined incidence of melanoma and non-melanoma skin cancer (NMSC) is greater than the incidence of all other malignancies in the US. Previously, we demonstrated that the endocannabinoid, arachidonoyl-ethanolamide (AEA), was a potent inducer of a
Autor:
William B. Monteith, Allison S. Danell, John M. Kenney, Sriramya Garapati, Christopher L. Wilson, Colin S. Burns, Anastasiia Kostenko
Publikováno v:
JBIC Journal of Biological Inorganic Chemistry. 23:1255-1263
Prothymosin-α is a small, multifunctional intrinsically disordered protein associated with cell survival and proliferation which binds multiple Zn2+ ions and undergoes partial folding. The interaction between prothymosin-α and at least two of its p
Autor:
Eman Soliman, Rukiyah Van Dross, Timothy L. Fitzgerald, Colin S. Burns, Daniel A. Ladin, Rene Escobedo, Li V. Yang
Publikováno v:
Molecular Cancer Therapeutics. 16:838-849
15-deoxy, Δ12,14-prostaglandin J2-ethanolamide, also known as 15-deoxy, Δ12,14-prostamide J2 (15d-PMJ2) is a novel product of the metabolism of arachidonoyl ethanolamide (AEA) by COX-2. 15d-PMJ2 preferentially induced cell death and apoptosis in tu
Autor:
Sriramya, Garapati, William, Monteith, Chris, Wilson, Anastasiia, Kostenko, John M, Kenney, Allison S, Danell, Colin S, Burns
Publikováno v:
Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry. 23(8)
Prothymosin-α is a small, multifunctional intrinsically disordered protein associated with cell survival and proliferation which binds multiple Zn
Publikováno v:
Inorganic Chemistry
Although the Cu2+-binding sites of the prion protein have been well studied when the protein is fully saturated by Cu2+, the Cu2+-loading mechanism is just beginning to come into view. Because the Cu2+-binding modes at low and intermediate Cu2+ occup
Autor:
Sriramya Garapati, Colin S. Burns
Publikováno v:
Journal of Peptide Science. 20:191-195
Use of the 4-pyridylmethyl ester group for side-chain protection of glutamic acid residues in solid-phase peptide synthesis enables switching of the charge state of a peptide from negative to positive, thus making detection by positive ion mode ESI-M
Publikováno v:
Journal of Biomolecular Structure and Dynamics. 29:825-842
Heavy metals have been implicated as the causative agents for the pathogenesis of the most prevalent neurodegenerative disease. Various mechanisms have been proposed to explain the toxic effects of metals ranging from metal-induced oxidation of prote
Autor:
Cijiang He, Colin S. Burns, Paul E. Klotman, J. Magarian Blander, Mary E. Klotman, G. Luca Gusella, Leif E. Sander, Arevik Mosoian, Avelino Teixeira
Publikováno v:
Proceedings of the National Academy of Sciences. 107:10178-10183
Induction of type I interferons (IFN) is a central feature of innate immune responses to microbial pathogens and is mediated via Toll-like receptor (TLR)-dependent and -independent pathways. Prothymosin-α (ProTα), a small acidic protein produced an
Publikováno v:
Journal of the American Society for Mass Spectrometry. 20:2199-2205
Electrospray ionization (ESI) mass spectrometry (MS) has proven to be an extremely powerful technique for studying the stoichiometry and binding strength of peptide–metal complexes. We have found a significant new problem in the ESI-MS of zinc–pe