Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Colin Ridler"'
Publikováno v:
British Journal of Haematology. 110:1003-1004
Publikováno v:
Blood. 104:4406-4406
CD123 constitutes the alpha subchain of the human interleukin 3 receptor (IL-3R). Interleukin 3 binds to its receptor with high and low affinities, induces tyrosine phosphorylation and promotes the proliferation and differentiation of haematopoietic
Autor:
Colin Ridler, Tim Milne, Jamie Cavenagh, Jude Fitzgibbon, Marion G. Macey, Matthew L. Smith, T. A. Lister, Samir G. Agrawal, Fatema Ebrahim
Publikováno v:
Blood. 104:3014-3014
High level expression of FLT3 in acute myeloid (AML) and lymphoid (ALL) leukaemias has been demonstrated by PCR techniques. This suggests that FLT3 and its ligand may play a significant role in the proliferation of leukaemic blast cells. Mutations of