Zobrazeno 1 - 10
of 60
pro vyhledávání: '"Colin Reardon"'
Publikováno v:
PLoS ONE, Vol 19, Iss 2, p e0299006 (2024)
Light microscopy methods have continued to advance allowing for unprecedented analysis of various cell types in tissues including the brain. Although the functional state of some cell types such as microglia can be determined by morphometric analysis
Externí odkaz:
https://doaj.org/article/17999eacfdb2451ca852046e15a88951
Autor:
Michael Cremin, Emmy Xue Yun Tay, Valerie T Ramirez, Kaitlin Murray, Rene K Nichols, Ingrid Brust-Mascher, Colin Reardon
Publikováno v:
PLoS Pathogens, Vol 19, Iss 12, p e1011576 (2023)
Mucosal immunity is critical to host protection from enteric pathogens and must be carefully controlled to prevent immunopathology. Regulation of immune responses can occur through a diverse range of mechanisms including bi-directional communication
Externí odkaz:
https://doaj.org/article/d5a299acc5384826b0f4bcac65dee670
Autor:
Valerie T Ramirez, Dayn R Godinez, Ingrid Brust-Mascher, Eric B Nonnecke, Patricia A Castillo, Mariana Barboza Gardner, Diane Tu, Jessica A Sladek, Elaine N Miller, Carlito B Lebrilla, Charles L Bevins, Melanie G Gareau, Colin Reardon
Publikováno v:
PLoS Pathogens, Vol 15, Iss 4, p e1007719 (2019)
The regulation of mucosal immune function is critical to host protection from enteric pathogens but is incompletely understood. The nervous system and the neurotransmitter acetylcholine play an integral part in host defense against enteric bacterial
Externí odkaz:
https://doaj.org/article/08cee2719d0f40789cb49ce1ac73fef5
Autor:
Laura Tarnawski, Colin Reardon, April S. Caravaca, Mauricio Rosas-Ballina, Michael W. Tusche, Anna R. Drake, LaQueta K. Hudson, William M. Hanes, Jian Hua Li, William R. Parrish, Kaie Ojamaa, Yousef Al-Abed, Michael Faltys, Valentin A. Pavlov, Ulf Andersson, Sangeeta S. Chavan, Yaakov A. Levine, Tak W. Mak, Kevin J. Tracey, Peder S. Olofsson
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Macrophage cytokine production is regulated by neural signals, for example in the inflammatory reflex. Signals in the vagus and splenic nerves are relayed by choline acetyltransferase+ T cells that release acetylcholine, the cognate ligand for alpha7
Externí odkaz:
https://doaj.org/article/52bcfec8bc364d5ab8731c82b886af1a
Autor:
Kaitlin Murray, Dayn Romero Godinez, Ingrid Brust-Mascher, Elaine Nicole Miller, Melanie G Gareau, Colin Reardon
Publikováno v:
PLoS ONE, Vol 12, Iss 7, p e0182416 (2017)
The nervous system plays a profound regulatory role in maintaining appropriate immune responses by signaling to immune cells. These immune cells, including B- and T-cells, can further act as intermediary messengers, with subsets of B- and T-cells exp
Externí odkaz:
https://doaj.org/article/db2f74df6dc44cbcacaf3028e11bd709
Publikováno v:
American Journal of Physiology-Lung Cellular and Molecular Physiology. 324:L53-L63
It is becoming increasingly appreciated that the nervous and immune systems communicate bidirectionally to regulate immunological outcomes in a variety of organs including the lung. Activation of neuronal signaling can be induced by inflammation, tis
Publikováno v:
Physiology. 38
Background: Vagus nerve stimulation (VNS) has recently been introduced as a nonpharmacological therapy for disease characterized by an exacerbated immune response, with clinical trials demonstrating its efficacy for autoimmunity and sepsis by reducin
Autor:
Colin Reardon
Publikováno v:
The Journal of Physiology. 600:4383-4384
Autor:
Patricia Stokes, Gonzalo Rabasa, Ingrid Brust-Mascher, Rene Nichols, Mélanie G. Gareau, Mariana Barboza, Carly Hennessey, Trina A. Knotts, Ciara E. Keogh, Matteo M. Pusceddu, Olivia Walsh, Mackenzie Honeycutt, Colin Reardon, Jessica A. Sladek
Publikováno v:
Infect Immun
Infection and immunity, vol 89, iss 9
Infection and immunity, vol 89, iss 9
Diarrheal diseases are a leading cause of death in children under the age of 5 years worldwide. Repeated early-life exposures to diarrheal pathogens can result in comorbidities including stunted growth and cognitive deficits, suggesting an impairment
Publikováno v:
The Journal of Immunology. 208:126.29-126.29
Acetylcholine (ACh), a well-known neurotransmitter, is produced by the action of choline acetyltransferase (ChAT). Recently, ChAT expression was shown also in leukocytes, however, its function there remains to be more fully explored. Flow cytometry r