Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Colin R. Lickwar"'
Autor:
Jayanth Jawahar, Alexander W. McCumber, Colin R. Lickwar, Caroline R. Amoroso, Sol Gomez de la Torre Canny, Sandi Wong, Margaret Morash, James H. Thierer, Steven A. Farber, Brendan J. M. Bohannan, Karen Guillemin, John F. Rawls
Publikováno v:
BMC Genomics, Vol 23, Iss 1, Pp 1-19 (2022)
Abstract Background The ability of animals and their microbiomes to adapt to starvation and then restore homeostasis after refeeding is fundamental to their continued survival and symbiosis. The intestine is the primary site of nutrient absorption an
Externí odkaz:
https://doaj.org/article/08d486c495ba4c1a9aabba407037981a
Autor:
Colin R Lickwar, J Gray Camp, Matthew Weiser, Jordan L Cocchiaro, David M Kingsley, Terrence S Furey, Shehzad Z Sheikh, John F Rawls
Publikováno v:
PLoS Biology, Vol 15, Iss 8, p e2002054 (2017)
The intestinal epithelium serves critical physiologic functions that are shared among all vertebrates. However, it is unknown how the transcriptional regulatory mechanisms underlying these functions have changed over the course of vertebrate evolutio
Externí odkaz:
https://doaj.org/article/580fa25accc343b88905af774dc81b4e
Autor:
Jennifer K Heppert, Colin R Lickwar, Matthew C Tillman, Briana R Davis, James M Davison, Hsiu-Yi Lu, Wei Chen, Elisabeth M Busch-Nentwich, David L Corcoran, John F Rawls
Publikováno v:
Genetics. 222(4)
Transcription factors play important roles in the development of the intestinal epithelium and its ability to respond to endocrine, nutritional, and microbial signals. Hepatocyte nuclear factor 4 family nuclear receptors are liganded transcription fa
Autor:
Cecelia Kelly, James M. Davison, Gilberto Padilla Mercado, John F. Rawls, Jennifer K. Heppert, Colin R. Lickwar
Publikováno v:
Nat Rev Gastroenterol Hepatol
The intestinal epithelium serves the unique and critical function of harvesting dietary nutrients, while simultaneously acting as a cellular barrier separating tissues from the luminal environment and gut microbial ecosystem. Two salient features of
Autor:
Colin R. Lickwar, James M. Davison, Cecelia Kelly, Gilberto Padilla Mercado, Jia Wen, Briana R. Davis, Matthew C. Tillman, Ivana Semova, Sarah F. Andres, Goncalo Vale, Jeffrey G. McDonald, John F. Rawls
The intestine constantly interprets and adapts to complex combinations of dietary and microbial stimuli. However, the transcriptional strategies by which the intestinal epithelium integrates these coincident sources of information remain unresolved.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::768bc37cbe5dd8278b25eeab3863415a
https://doi.org/10.1101/2021.11.01.465976
https://doi.org/10.1101/2021.11.01.465976
Autor:
Sol Gomez de la Torre Canny, Sandi Wong, John F. Rawls, Caroline R. Amoroso, Karen Guillemin, Alexander W. McCumber, Colin R. Lickwar, Jayanth Jawahar, Brendan J. M. Bohannan
Background: The ability of animals and their microbiomes to adapt to starvation and then restore homeostasis after refeeding is fundamental to their continued survival and symbiosis. The intestine is the primary site of nutrient absorption and microb
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::34378bb3de027c7a9b4e50b019f484e9
https://doi.org/10.21203/rs.3.rs-120052/v1
https://doi.org/10.21203/rs.3.rs-120052/v1
Autor:
Jason M. Ridlon, Gilberto Padilla Mercado, Genta Kakiyama, Taylor Crooks, Cecelia Kelly, Colin R. Lickwar, Jia Wen, Heidi L. Doden, Alyssa Volland, Jordan L. Cocchiaro, John F. Rawls
Publikováno v:
Science Advances
Genetic analysis in zebrafish reveals conserved and novel aspects of nuclear receptor Fxr function and bile salt signaling.
Bile salt synthesis, secretion into the intestinal lumen, and resorption in the ileum occur in all vertebrate classes. In
Bile salt synthesis, secretion into the intestinal lumen, and resorption in the ileum occur in all vertebrate classes. In
Autor:
Alyce M. Martin, Rodger A. Liddle, Lihua Ye, John D. Thompson, Daniel W. Thorpe, Colin R. Lickwar, Jinhu Wang, Damien J. Keating, Kenneth D. Poss, Sairam V. Jabba, Jon Clardy, John F. Rawls, Hsiu-Yi Lu, Sven-Eric Jordt, Munhyung Bae, Chelsi D. Cassilly
Publikováno v:
Cell Host Microbe
SUMMARYThe intestinal epithelium senses nutritional and microbial stimuli using epithelial sensory enteroendocrine cells (EECs). EECs can communicate nutritional information to the nervous system, but similar mechanisms for microbial information are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37a22422f9af3b92932fd48dbf1155bb
https://doi.org/10.1101/2020.06.09.142133
https://doi.org/10.1101/2020.06.09.142133
Autor:
James M. Davison, Colin R. Lickwar, John F. Rawls, Greg E. Crawford, Ghislain Breton, Lingyun Song
Publikováno v:
Genome Research. 27:1195-1206
Microbiota influence diverse aspects of intestinal physiology and disease in part by controlling tissue-specific transcription of host genes. However, host genomic mechanisms mediating microbial control of intestinal gene expression are poorly unders