Zobrazeno 1 - 10
of 57
pro vyhledávání: '"Colin R Gardner"'
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-7 (2024)
Abstract There is a long history of linking the perceptions of temperature and color (the “Hue-heat hypothesis”): red (R) and yellow (Y) are often considered warm, whereas blue (B) and green (G) are cool. Past studies, however, have largely used
Externí odkaz:
https://doaj.org/article/819b4c0b33ea49109dfb78f23d3a17cd
Publikováno v:
Current Eye Research. :1-6
Autor:
Colin R. Gardner
Publikováno v:
Cell Biology International. 31:672-682
Under the influence of RANKL, in the presence of M-CSF, monocyte/macrophage precursor cells entered the osteoclast lineage and expressed the osteoclast marker tartrate-resistant acid phosphatase (TRAP). These cells were motile and began to differenti
Autor:
Colin R. Gardner, Dina Berkovitz, Jean-Francois Marier, Zhong Zhang, Hongming Chen, Orn Almarsson
Publikováno v:
Pharmaceutical Research. 22:356-361
Propofol is a widely used anesthetic agent with highly desirable fast "on" and "off" effects. It is currently formulated as lipid emulsions, which are known to support microbial growth. In this study, a novel, lipid-free nanodispersion formulation of
Autor:
Hongming Chen, Orn Almarsson, Sherry L. Morissette, Joseph Marchionna, Javier Gonzalez-Zugasti, Michael J. Cima, Doug Levinson, Julie Monagle, Steve Ellis, Colin R. Gardner, Zhong Zhang, Szu Wang, Matthew Peterson, Chris McNulty, Anthony V. Lemmo, Alasdair Johnson
Publikováno v:
Computers & Chemical Engineering. 28:943-953
This presentation describes the application of novel high throughput physical–chemical technologies to the pharmaceutical discovery and development process. The rationale for such platforms is described in light of the changes that have occurred in
Publikováno v:
Cytokine. 12:774-779
The soluble IL-6 receptor (sIL-6R) can increase IL-6-induced signalling by forming a complex with IL-6 and membrane-bound gp130 (the receptor beta chain which transduces signals). The conditions affecting this response to sIL-6R were studied using fi
Autor:
Jeannette Soria, Francis Frankenne, Véronique Trochon, He Lu, Colin R Gardner, Marc Vasse, Claudine Soria, Annick Thomaidis, Hong Li
Publikováno v:
Angiogenesis. 2:277-285
Recently two metalloproteinase, disintegrin, cysteine proteins (MDCs), also called ADAMs were identified on endothelial cells. However the role of these ADAMs are not defined on these cells. In order to elucidate whether ADAMs associated with endothe
Publikováno v:
Drug Development Research. 22:309-320
The efficacy of a series of novel imidazoquinolines and imidazopyrimidines at benzodiazepine (BDZ) receptors was assessed using in vivo models: food-motivated conflict in rats, stress-induced ultrasounds in rat pups, leptazol seizures in mice, and su
Autor:
Paula Budhram, Colin R. Gardner
Publikováno v:
Drug Development Research. 22:339-347
Male Lister rats were trained to discriminate either chlordiazepoxide (CDZP), the benzodiazepine (BDZ) receptor partial agonist RU32698, or leptazol from vehicle on a fixed ratio 20 schedule. From 10 imidazopyrimidine BDZ receptor ligands tested four
Autor:
Vernon James, Colin R. Gardner
Publikováno v:
Drug Development Research. 22:331-337
Five selected imidazopyrimidine ligands for benzodiazepine receptors which show nonsedative anxiolytic behavioral profiles, were tested for their ability to reverse arousal induced by intermittent footshock stress in sleeping rats. RU32698, RU32759,