Zobrazeno 1 - 10
of 53
pro vyhledávání: '"Colin R Campbell"'
Autor:
Colin R. Campbell, Tim J. Sullivan
Publikováno v:
Proceedings of the Annual Conference of CAIS / Actes du congrès annuel de l'ACSI.
see attached
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::81dd13658b25559e13eca427bd3ba258
https://doi.org/10.29173/cais1278
https://doi.org/10.29173/cais1278
Autor:
Arnold Groehler, Colin R Campbell, Xun Ming, Natalia Y. Tretyakova, Erin D. Michaelson-Richie, Peter W. Villalta
Publikováno v:
DNA Repair (Amst)
1,1,2,2- Cis-diamminedichloroplatinum (II) (cisplatin) is a chemotherapeutic agent widely used in the clinic to treat various cancers. The antitumor activity of cisplatin is generally attributed to its ability to form intrastrand and interstrand DNA-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43fdb201be94cf929e1eae1717cf6e43
https://europepmc.org/articles/PMC8177102/
https://europepmc.org/articles/PMC8177102/
Publikováno v:
DNA repair
While mammalian mitochondria are known to possess a robust base excision repair system, direct evidence for the existence of additional mitochondrial DNA repair pathways is elusive. Herein a PCR-based assay was employed to demonstrate that plasmids c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52af89348a953684957d351605bb5c86
https://doi.org/10.1016/j.dnarep.2020.103026
https://doi.org/10.1016/j.dnarep.2020.103026
Autor:
Sheila S. David, Douglas M. Banda, Nicole N. Nuñez, Shaofei Ji, Natalia Y. Tretyakova, Colin R Campbell, Leona D. Samson, Amelia H. Manlove, Bhaskar Malayappan, Susith Wickramaratne
Publikováno v:
Biochemistry. 55:6070-6081
The important industrial and environmental carcinogen 1,3-butadiene (BD) forms a range of adenine adducts in DNA, including N6-(2-hydroxy-3-buten-1-yl)-2′-deoxyadenosine (N6-HB-dA), 1,N6-(2-hydroxy-3-hydroxymethylpropan-1,3-diyl)-2′-deoxyadenosin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4169624eea734114559a4a54d57a8b83
https://doi.org/10.1021/acs.biochem.6b00553
https://doi.org/10.1021/acs.biochem.6b00553
Publikováno v:
Chemical Research in Toxicology. 29:190-202
N,N-Bis-(2-chloroethyl)-phosphorodiamidic acid (phosphoramide mustard, PM) and N,N-bis-(2-chloroethyl)-amine (nornitrogen mustard, NOR) are the two biologically active metabolites of cyclophosphamide, a DNA alkylating drug commonly used to treat lymp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe8628ee46dc0e923b5631437dc7c81f
https://doi.org/10.1021/acs.chemrestox.5b00430
https://doi.org/10.1021/acs.chemrestox.5b00430
Autor:
Anna E. Prizment, Cavan S. Reilly, Heather H. Nelson, Sara Putnam, Michelle A. Roesler, Colin R Campbell, Bharat Thyagarajan, DeAnn Lazovich, Logan G. Spector, Jen Poynter
Publikováno v:
Cancer Epidemiology, Biomarkers & Prevention. 29:A24-A24
Due to evolving population demographics, altered exposures, and new technology, new cohorts need to be initiated. Here we report our efforts from a pilot cohort study of the 10,000 Families Study (10KFS). The goal of the pilot is to establish the inf
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6220f613bb3f7246c3eabf16b04bf3ae
https://doi.org/10.1158/1538-7755.modpop19-a24
https://doi.org/10.1158/1538-7755.modpop19-a24
Autor:
Colin R Campbell, Lisa N. Chesner
Publikováno v:
Journal of Visualized Experiments : JoVE
The purpose of this method is to provide a flexible, rapid, and quantitative technique to examine the kinetics of DNA-protein crosslink (DPC) repair in mammalian cell lines. Rather than globally assaying removal of xenobiotic-induced or spontaneous c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69741cba03e74469e849acffec9144fb
https://doi.org/10.3791/57413
https://doi.org/10.3791/57413
Autor:
Colin R Campbell, Lisa N. Chesner
Publikováno v:
DNA repair. 62
DNA-protein crosslinks (DPCs) are complex DNA lesions that induce mutagenesis and cell death. DPCs are created by common antitumor drugs, reactive oxygen species, and endogenous aldehydes. Since these agents create other types of DNA damage in additi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b336b3acd9a87b76b24b1365d7d05f10
https://pubmed.ncbi.nlm.nih.gov/29413806
https://pubmed.ncbi.nlm.nih.gov/29413806
Autor:
Colin R Campbell, Xun Ming, Erin D. Michaelson-Richie, Natalia Y. Tretyakova, Peter W. Villalta, Arnold Groehler
Platinum-based antitumor drugs such as 1,1,2,2-cis-diamminedichloroplatinum(II) (cisplatin), carboplatin, and oxaliplatin are currently used to treat nearly 50% of all cancer cases, and novel platinum based agents are under development. The antitumor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c6d56d88ba19734fe7be5575a6100d2
https://europepmc.org/articles/PMC5567688/
https://europepmc.org/articles/PMC5567688/
Autor:
Melissa Campion, Colin R Campbell, Erin D. Michaelson-Richie, Teshome B. Gherezghiher, Susith Wickramaratne, Sreenivas Kanugula, Anthony E. Pegg, Jamie Kurtz, Xun Ming, Natalia Y. Tretyakova
Publikováno v:
Biochemistry. 52:3171-3181
Although cytotoxic alkylating agents possessing two electrophilic reactive groups are thought to act by cross-linking cellular biomolecules, their exact mechanisms of action have not been established. In cells, these compounds form a mixture of DNA l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72c44c7dfde0de32e6849f6f06be9f0f
https://doi.org/10.1021/bi400273m
https://doi.org/10.1021/bi400273m