Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Colin R A, Hewitt"'
Publikováno v:
Immunology. 108:109-115
The airway epithelium is the first cellular component of the lung to be encountered by the particles and pathogens present in inhaled air. In addition to its role as a physical barrier, the immunological activity of the airway epithelium is an essent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df18750ff93b4313f28e4f0c3d25502d
https://doi.org/10.1046/j.1365-2567.2003.01539.x
https://doi.org/10.1046/j.1365-2567.2003.01539.x
Publikováno v:
American Journal of Respiratory and Critical Care Medicine. 162:S40-S43
It seems certain that environmental (not genetic) factors are responsible for the remarkable increase in prevalence of allergic respiratory diseases over the last 20 yr (1). One such factor might be improved hygiene, which has led to fewer childhood
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9993363b049a925b980e91963d331da
https://doi.org/10.1164/ajrccm.162.supplement_1.maic-11
https://doi.org/10.1164/ajrccm.162.supplement_1.maic-11
Autor:
E. Holme, S. Fletcher, W.S. Hillis, K.L. Woods, Colin R. A. Hewitt, Iain B. Squire, Wendy J. Lawley
Publikováno v:
European Heart Journal. 20:1245-1252
Aims Administration of streptokinase results in an immunological response which may lead to increased risk of anaphylactic reaction or reduced thrombolytic efficacy on repeat administration. For these reasons current recommendations suggest that stre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a920cbec2c53f9a6241fd24913faf416
https://doi.org/10.1053/euhj.1999.1528
https://doi.org/10.1053/euhj.1999.1528
Publikováno v:
Clinical & Experimental Allergy. 27:201-207
BACKGROUND Exposure of the skin or respiratory tract to proteinases is frequently associated with allergic sensitization. This is of particular significance in the domestic indoor environment where the proteolytic activity of Der p I, the group I all
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e96c64ec06a7774d214e5a22ea14d57
https://doi.org/10.1111/j.1365-2222.1997.tb00694.x
https://doi.org/10.1111/j.1365-2222.1997.tb00694.x
Publikováno v:
Hybridoma. 11:701-713
The generation of a panel of monoclonal antibodies specific for different variable (V) regions of human T cell receptors will be of great importance in the study of T cell-mediated diseases. However, relatively few such reagents exist, due in part to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0fd410ff0848c82bde0770d8bed9f76
https://doi.org/10.1089/hyb.1992.11.701
https://doi.org/10.1089/hyb.1992.11.701
Autor:
Jonathan R. Lamb, Colin R. A. Hewitt, John D. Hayball, Mark Hill, Robyn E O'Hehir, Michael John Owen
Publikováno v:
The Journal of Experimental Medicine
The Staphylococcal enterotoxin superantigens stimulate vigorous responses in T cells bearing certain T cell antigen receptor (TCR) V beta regions. In addition to activation, these superantigens also impart negative signals to T cells resulting in a p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa6f283d348bc215b3aa18767f612f97
http://europepmc.org/articles/PMC2119262
http://europepmc.org/articles/PMC2119262
Publikováno v:
Exercise immunology review. 15
Physical stress induces a marked redistribution of T lymphocytes that may be influenced by carbohydrate (CHO) availability, yet the effect of these on T lymphocyte migration towards infected tissue is unknown. Therefore, the aim of this study was to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7ac55b2052052edf7fb8fa05c0debef0
https://pubmed.ncbi.nlm.nih.gov/19957874
https://pubmed.ncbi.nlm.nih.gov/19957874
Previously, we had shown that T cells accumulated in peribronchiolar and perivascular areas of lungs soon after intranasal infection with Streptococcus pneumoniae . We have now presented new evidence, using major histocompatibility class II-deficient
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::714d382c3878cd5c81627f7f0cba4962
https://europepmc.org/articles/PMC387852/
https://europepmc.org/articles/PMC387852/
Publikováno v:
Journal of leukocyte biology. 74(1)
Eosinophil recruitment to airway tissue is a key feature of asthma, and release of a wide variety of toxic mediators from eosinophils leads to the tissue damage that is a hallmark of asthma pathology. Factors that control the release of these toxic m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c398d8d36d7372bbec17a7a3e8bb6243
https://pubmed.ncbi.nlm.nih.gov/12832443
https://pubmed.ncbi.nlm.nih.gov/12832443
Publikováno v:
Journal of leukocyte biology. 73(1)
The proteolytic activities frequently associated with sources of allergens and parasite secretions have been suggested as important immunomodulators. We have investigated whether the protease activity of the house dust mite allergen Der p1 and the se
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c989d31155925c502804e946f8c1095b
https://pubmed.ncbi.nlm.nih.gov/12525574
https://pubmed.ncbi.nlm.nih.gov/12525574