Zobrazeno 1 - 10
of 79
pro vyhledávání: '"Colin N Dewey"'
Publikováno v:
PLoS Computational Biology, Vol 11, Iss 10, p e1004491 (2015)
Segmental duplications and other highly repetitive regions of genomes contribute significantly to cells' regulatory programs. Advancements in next generation sequencing enabled genome-wide profiling of protein-DNA interactions by chromatin immunoprec
Externí odkaz:
https://doaj.org/article/97434afb10574b909df7e73628199e90
Autor:
Ron Stewart, Cynthia Alexander Rascón, Shulan Tian, Jeff Nie, Chris Barry, Li-Fang Chu, Hamisha Ardalani, Ryan J Wagner, Mitchell D Probasco, Jennifer M Bolin, Ning Leng, Srikumar Sengupta, Michael Volkmer, Bianca Habermann, Elly M Tanaka, James A Thomson, Colin N Dewey
Publikováno v:
PLoS Computational Biology, Vol 9, Iss 3, p e1002936 (2013)
The salamander has the remarkable ability to regenerate its limb after amputation. Cells at the site of amputation form a blastema and then proliferate and differentiate to regrow the limb. To better understand this process, we performed deep RNA seq
Externí odkaz:
https://doaj.org/article/b8b1636cb3834d94acff20c9e675891e
Publikováno v:
PLoS Genetics, Vol 5, Iss 11, p e1000729 (2009)
Population genetic theory predicts discordance in the true phylogeny of different genomic regions when studying recently diverged species. Despite this expectation, genome-wide discordance in young species groups has rarely been statistically quantif
Externí odkaz:
https://doaj.org/article/c484651726f649d794ede12709290b3f
Autor:
David J Begun, Alisha K Holloway, Kristian Stevens, Ladeana W Hillier, Yu-Ping Poh, Matthew W Hahn, Phillip M Nista, Corbin D Jones, Andrew D Kern, Colin N Dewey, Lior Pachter, Eugene Myers, Charles H Langley
Publikováno v:
PLoS Biology, Vol 5, Iss 11, p e310 (2007)
The population genetic perspective is that the processes shaping genomic variation can be revealed only through simultaneous investigation of sequence polymorphism and divergence within and between closely related species. Here we present a populatio
Externí odkaz:
https://doaj.org/article/6b804cd42a204968b1a74d54a4da1c4d
Publikováno v:
iScience, Vol 27, Iss 4, Pp 109532- (2024)
Summary: Wound healing is impaired by infection; however, how microbe-induced inflammation modulates tissue repair remains unclear. We took advantage of the optical transparency of zebrafish and a genetically tractable microbe, Listeria monocytogenes
Externí odkaz:
https://doaj.org/article/1f7e2c76438f40779d2cde0cb1d6f736
Publikováno v:
PLoS Computational Biology, Vol 2, Iss 6, p e73 (2006)
The classic algorithms of Needleman-Wunsch and Smith-Waterman find a maximum a posteriori probability alignment for a pair hidden Markov model (PHMM). To process large genomes that have undergone complex genome rearrangements, almost all existing who
Externí odkaz:
https://doaj.org/article/d360d58eaa9a438f85bac0f9aa7a6438
Autor:
Nihal Ahmad, Vijayasaradhi Setaluri, Colin N. Dewey, Wei Huang, Ting Ye, Chandra K. Singh, Mary A. Ndiaye, Gagan Chhabra, Shengqin Su
Supplementary files to support the manuscript, including antibody and cell line mutational information and confirmation/setup information for different experiments.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95559ed94040c4f224e59c9810cbdab1
https://doi.org/10.1158/1535-7163.22520634
https://doi.org/10.1158/1535-7163.22520634
Autor:
Nihal Ahmad, Vijayasaradhi Setaluri, Colin N. Dewey, Wei Huang, Ting Ye, Chandra K. Singh, Mary A. Ndiaye, Gagan Chhabra, Shengqin Su
Melanoma is one of the most serious forms of skin cancer, and its increasing incidence coupled with nonlasting therapeutic options for metastatic disease highlights the need for additional novel approaches for its management. In this study, we determ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::144269cc8dcc9baff55b6a02e56d0613
https://doi.org/10.1158/1535-7163.c.6542709
https://doi.org/10.1158/1535-7163.c.6542709
Autor:
Isabela Fraga de Andrade, Kirby D. Johnson, Charu Mehta, Colin N. Dewey, Uttiya Basu, Emery H. Bresnick
Publikováno v:
Blood advances.
The RNA-regulatory exosome complex (EC) posttranscriptionally and cotranscriptionally processes and degrades RNAs in a context-dependent manner. Although the EC functions in diverse cell types, its contributions to stem and progenitor cell developmen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b51f5c03e095b76a0da00d3a42d0aa19
https://pubmed.ncbi.nlm.nih.gov/36161469
https://pubmed.ncbi.nlm.nih.gov/36161469
Publikováno v:
Nucleic Acids Research
Cellular differentiation requires vast remodeling of transcriptomes, and therefore machinery mediating remodeling controls differentiation. Relative to transcriptional mechanisms governing differentiation, post-transcriptional processes are less well
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ed67af2ed93a501c4a4e2529433c852
http://europepmc.org/articles/PMC8450083
http://europepmc.org/articles/PMC8450083