Neurite outgrowth deficits caused by rare PLXNB1 mutation in pediatric bipolar disorder

Autor: Guang Yang, H. M. Arif Ullah, Ethan Parker, Bushra Gorsi, Mark Libowitz, Colin Maguire, Jace B. King, Hilary Coon, Melissa Lopez-Larson, Jeffrey S. Anderson, Mark Yandell, Alex Shcheglovitov

Publikováno v: Molecular Psychiatry.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::da54f0609f9263e4fdb678b4a0b134d9
https://doi.org/10.1038/s41380-023-02035-w

Neurite outgrowth deficits caused by rare PLXNB1 mutation in pediatric bipolar disorder

Autor: Guang Yang, Ethan Parker, Bushra Gorsi, Mark Liebowitz, Colin Maguire, Jace B. King, Hilary Coon, Melissa Lopez-Larson, Jeffrey Anderson, Mark Yandell, Alex Shcheglovitov

Pediatric Bipolar Disorder (PBD) is a severe mood dysregulation condition that affects 0.5–1% of children and teens in the United States. It is associated with recurrent episodes of psychosis and depression and an increased risk of suicidality. How

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8e722663c6af76e75afe121161b84920
https://doi.org/10.1101/2022.05.06.22274499

A common allele of HLA mediates asymptomatic SARS-CoV-2 infection

Autor: Danillo G. Augusto, Tasneem Yusufali, Joseph J. Sabatino, Noah D. Peyser, Lawton D. Murdolo, Xochitl Butcher, Victoria Murray, Vivian Pae, Sannidhi Sarvadhavabhatla, Fiona Beltran, Gurjot Gill, Kara Lynch, Cassandra Yun, Colin Maguire, Michael J. Peluso, Rebecca Hoh, Timothy J. Henrich, Steven G. Deeks, Michelle Davidson, Scott Lu, Sarah A. Goldberg, J. Daniel Kelly, Jeffrey N. Martin, Cynthia A. Viera-Green, Stephen R. Spellman, David J. Langton, Sulggi Lee, Gregory M. Marcus, Jeffrey E. Olgin, Mark J. Pletcher, Stephanie Gras, Martin Maiers, Jill A. Hollenbach

Despite some inconsistent reporting of symptoms, studies have demonstrated that at least 20% of individuals infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) will remain asymptomatic. Although most global efforts have focused

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::65901303a2c4c3f3bcee7ba55f5e04ba
https://doi.org/10.1101/2021.05.13.21257065

Genetic Mapping of a new

Autor: Jamie L, Siders, Kayla L, Bieser, Danielle R, Hamill, Erika C, Acosta, Olivia K, Alexander, Humza I, Ali, Micah J, Anderson, Hayden R, Arrasmith, Mustafa, Azam, Nikki J, Beeman, Hassan, Beydoun, Lauren J, Bishop, Morgan D, Blair, Brianna, Bletch, Heather R, Bline, Jennifer C, Brown, Kelly M, Burns, Karina C, Calagua, Lexie, Chafin, William Ah, Christy, Carlyn, Ciamacco, Hannah, Cizauskas, Caitlyn M, Colwell, Abigail R, Courtright, Lucero, Diaz Alavez, Rayne Is, Ecret, Fatima, Edriss, Taylor G, Ellerbrock, Madison M, Ellis, Erica M, Extine, Eric, Feldman, Luke J, Fickenworth, Caroline M, Goeller, Alexis S, Grogg, Yailine, Hernandez, Abigail, Hershner, Megan M, Jauss, Leyre, Jimenez Garcia, Katey E, Franks, Ethan T, Kazubski, Emily R, Landis, Jon, Langub, Tia N, Lassek, Triet C, Le, Julia M, Lee, Daniel P, Levine, Phoebe J, Lightfoot, Natasha, Love, Ali, Maalhagh-Fard, Colin, Maguire, Brynna E, McGinnis, Bhargavi V, Mehta, Veronica, Melendrez, Zimri E, Mena, Seth, Mendell, Petra, Montiel-Garcia, Autumn S, Murry, Riley A, Newland, Ryan M, Nobles, Neha, Patel, Yashodhara, Patil, Cassidy L, Pfister, Victoria, Ramage, Mya R, Ray, Joseph, Rodrigues, Victoria C, Rodriquez, Yara, Romero, Alexandra M, Scott, Nicholas, Shaba, Samantha, Sieg, Kayla, Silva, Sahiba, Singh, Aleksandria J, Spargo, Savanna J, Spitnale, Nicole, Sweeden, Logan, Tague, Breanna M, Tavernini, Kathleen, Tran, Liselle, Tungol, Kylie A, Vestal, Amber, Wetherbee, Kayla M, Wright, Anthony T, Yeager, Rehab, Zahid, Jacob D, Kagey

Publikováno v: microPublication Biology

Genetic screens provide a mechanism to identify genes involved with different cellular and organismal processes. Using a Flp/FRT screen in the Drosophila eye we identified mutations that result in alterations and de-regulation of cell growth and divi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::1878c94ed367199745ad5eba98387b24
https://pubmed.ncbi.nlm.nih.gov/33851093

Absence of Msx2 does not affect cardiac conduction or rescue conduction defects associated with Nkx2-5 mutation

Autor: Hiroko Wakimoto, T B S Colin Maguire, Seigo Izumo, Patrick Y. Jay, Charles I. Berul

Publikováno v: Journal of cardiovascular electrophysiology. 16(1)

Msx2 and Cardiac Conduction. Introduction: The transcription factors governing embryonic development of the AV conduction system are largely unknown. Heterozygous mutations of the cardiac transcription factor Nkx2-5 causeAV conduction defects, which

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e873acfc591e532c67a3dd62cf0b697
https://pubmed.ncbi.nlm.nih.gov/15673394