Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Colin M. Young"'
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Abstract Sickle cell disease (SCD) is a group of inherited genetic conditions associated with lifelong complications and increased healthcare resource utilization. Standard treatment for SCD in the US varies based on stage of the disease and observed
Externí odkaz:
https://doaj.org/article/538cdffe961341efbf57f399ebeb6a38
Publikováno v:
Data in Brief, Vol 41, Iss , Pp 107891- (2022)
The recent marketing approval of several durable gene and cell therapies (2017-2020), together with observations that 7,000 monogenic indications and many cancers were potential targets, led to concern about the potential economic impact of such ther
Externí odkaz:
https://doaj.org/article/ef8fd81c323b4de8bf6100fdd0fe15fa
Publikováno v:
Drug Discovery Today. 27:17-30
Durable cell and gene therapies potentially transform patient lives, but payers fear unsustainable costs arising from the more than 1000 therapies in the development pipeline. A novel multi-module Markov chain Monte Carlo-based model projects product
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41142ffc28dcec03ba568855a512cf38
https://doi.org/10.1016/j.drudis.2021.09.001
https://doi.org/10.1016/j.drudis.2021.09.001
Autor:
Nikola A. Ivica, Colin M. Young
Publikováno v:
Healthcare, Vol 9, Iss 1062, p 1062 (2021)
Healthcare
Healthcare
Chimeric antigen receptor and T-cell receptor (CAR-T/TCR-T) cellular immunotherapies have shown remarkable success in the treatment of some refractory B-cell malignancies, with potential to provide durable clinical response for other types of cancer.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8434dd01beaf1c9e2e785b2a9ce6617
https://www.mdpi.com/2227-9032/9/8/1062
https://www.mdpi.com/2227-9032/9/8/1062
Autor:
Colin M. Young, Nikola A. Ivica
Chimeric antigen receptor and T-cell receptor (CAR-T/TCR) cellular immunotherapies have shown remarkable success in the treatment of some refractory B-cell malignancies, with potential to provide durable clinical response for other types of cancer. I
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bcfdd7032014dc7ea9c55cfb06fcfcb8
Publikováno v:
Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research. 22(6)
Objectives To estimate, at the indication level, durable gene and cellular therapy new product launches in the United States through 2030, and the number of treated patients. Methods A statistical analysis of clinical trials pipeline data and disease
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58a4d5159152637437be3a71a60729ce
https://pubmed.ncbi.nlm.nih.gov/31198178
https://pubmed.ncbi.nlm.nih.gov/31198178
Autor:
Colin M. Young, Jonathan Salcedo
Publikováno v:
Value in Health. 22:S79-S80
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f3fbd003a4eed62fe077036141724c4a
https://doi.org/10.1016/j.jval.2019.04.250
https://doi.org/10.1016/j.jval.2019.04.250
Publikováno v:
Blood. 134:4671-4671
Introduction: Sickle cell disease (SCD) is an inherited blood disorder with significant healthcare resource utilization in the United States (US). The clinical management throughout the course of the disease is variable. Children born with SCD in the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::722e62441cc5deaf405f417856b6bdd9
https://doi.org/10.1182/blood-2019-122597
https://doi.org/10.1182/blood-2019-122597
Autor:
Colin M. Young
Publikováno v:
Ibis. 112:330-335
Summary A population of Common Shelducks on the Ythan Estuary was studied intensively from December 1961 to August 1964, with special attention to territoriality and population regulation. Many of the shelducks in this population establish mutually e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1547b6dfcca68c84b50abe7afca479bf
https://doi.org/10.1111/j.1474-919x.1970.tb00110.x
https://doi.org/10.1111/j.1474-919x.1970.tb00110.x
Publikováno v:
Managerial Finance. 18:49-62
The objective of this paper is to demonstrate how to use the Elton, Gruber, and Padberg [1978] model to construct optimal portfolios and to facilitate the use of this paradigm by providing an example of how the technique is used. The EGP model uses t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::492cbbf696987d4f98076773d1d3ed31
https://doi.org/10.1108/eb018449
https://doi.org/10.1108/eb018449