Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Colin M. Skinner"'
Publikováno v:
Skeletal Muscle, Vol 10, Iss 1, Pp 1-16 (2020)
Abstract Skeletal muscle is among the most age-sensitive tissues in mammal organisms. Significant changes in its resident stem cells (i.e., satellite cells, SCs), differentiated cells (i.e., myofibers), and extracellular matrix cause a decline in tis
Externí odkaz:
https://doaj.org/article/4900ae326d2b4794a49616780a2cf7f3
Autor:
Melod Mehdipour, Payam Amiri, Chao Liu, Jonalyn DeCastro, Cameron Kato, Colin M. Skinner, Michael J. Conboy, Kiana Aran, Irina M. Conboy
Publikováno v:
Nature protocols, vol 17, iss 11
Nat Protoc
Nat Protoc
We describe a small-animal blood exchange approach developed for aging research as an alternative to heterochronic parabiosis or plasma injections. In parabiosis, animals are surgically coupled, which has several disadvantages, including difficulty c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6fe2d1fea41411b74118880d22fd5ef5
https://escholarship.org/uc/item/1c52m9gj
https://escholarship.org/uc/item/1c52m9gj
Autor:
Michael J. Conboy, Irina M. Conboy, Nathan D. Wong, Cameron Kato, Jessy Etienne, Melod Mehdipour, Dobri D. Kiprov, Chao Liu, Colin M. Skinner, Michael Lieb
Publikováno v:
Aging, vol 12, iss 10
Heterochronic blood sharing rejuvenates old tissues, and most of the studies on how this works focus on young plasma, its fractions, and a few youthful systemic candidates. However, it was not formally established that young blood is necessary for th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e63d75735ba7607e201ba0d35471ca9
https://doi.org/10.18632/aging.103418
https://doi.org/10.18632/aging.103418
Publikováno v:
Skeletal Muscle, Vol 10, Iss 1, Pp 1-16 (2020)
Skeletal muscle, vol 10, iss 1
Skeletal Muscle
Skeletal muscle, vol 10, iss 1
Skeletal Muscle
Skeletal muscle is among the most age-sensitive tissues in mammal organisms. Significant changes in its resident stem cells (i.e., satellite cells, SCs), differentiated cells (i.e., myofibers), and extracellular matrix cause a decline in tissue homeo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::225e40c4e0375dea0048e3197447a98b
https://doaj.org/article/4900ae326d2b4794a49616780a2cf7f3
https://doaj.org/article/4900ae326d2b4794a49616780a2cf7f3
Autor:
Taha Mehdipour, Melod Mehdipour, Nathan D. Wong, Colin M. Skinner, Michael J. Conboy, Irina M. Conboy, Chia Chien Chen, Yi Zuo, Chao Liu, Ok-Hee Jeon
Publikováno v:
GeroScience, vol 43, iss 1
GeroScience
GeroScience
Our recent study has established that young blood factors are not causal, nor necessary, for the systemic rejuvenation of mammalian tissues. Instead, a procedure referred to as neutral blood exchange (NBE) that resets signaling milieu to a pro-regene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1406612541e2f3294fb57408525f0907
https://escholarship.org/uc/item/3sp7w65p
https://escholarship.org/uc/item/3sp7w65p
Autor:
Fuguo Jiang, Song Li, Kazunori Kataoka, Wen Chin Huang, Hui Liu, Kevin Chang, Hyo Min Park, Niren Murthy, Melod Mehdipour, Mark A. DeWitt, Michael J. Conboy, Jacob E. Corn, Tamanna Shobha, Nicolas Bray, Irina M. Conboy, Colin M. Skinner, Hyun Jin Kim, Freeman Lan, Anirudh Rao, Jennifer A. Doudna, Vanessa A Mackley, Kunwoo Lee
Publikováno v:
Nature biomedical engineering, vol 1, iss 11
Nature biomedical engineering
Nature biomedical engineering
CRISPR/Cas9-based therapeutics, especially those that can correct gene mutations via homology directed repair (HDR), have the potential to revolutionize the treatment of genetic diseases. However, HDR-based therapeutics are challenging to develop bec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81bab31ea8f695f7d4fd04b48015f791
https://escholarship.org/uc/item/8zb2b2vn
https://escholarship.org/uc/item/8zb2b2vn
Autor:
Harry Platt, Victor Lambert, W. Mansfield Cooper, Colin M. Skinner, Fergus R. Ferguson, Robert W. Platt, Richard Johnson, Norris M. Agnew
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::daaf2dafd3a040d1c1c1e99eeae37d9d
https://europepmc.org/articles/PMC1872206/
https://europepmc.org/articles/PMC1872206/