Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Colin M. Muir"'
Autor:
Vinita Bharat, Aarooran S. Durairaj, Roeland Vanhauwaert, Li Li, Colin M. Muir, Sujyoti Chandra, Chulhwan S. Kwak, Yann Le Guen, Pawan Nandakishore, Chung-Han Hsieh, Stefano E. Rensi, Russ B. Altman, Michael D. Greicius, Liang Feng, Xinnan Wang
Publikováno v:
Cell Reports, Vol 42, Iss 12, Pp 113544- (2023)
Summary: Dysregulated iron or Ca2+ homeostasis has been reported in Parkinson’s disease (PD) models. Here, we discover a connection between these two metals at the mitochondria. Elevation of iron levels causes inward mitochondrial Ca2+ overflow, th
Externí odkaz:
https://doaj.org/article/d232850709d248d9838e814e06aa9ca2
Autor:
Joshua L. Andersen, Manabu Kurokawa, Stephen R. Piccolo, Katherine K. McCormack, Tyler Heaton, Sandeep Kaur, Christina M. Egbert, Eranga R. Balasooriya, Riley Eastmond, A.G. Pramoda Sahankumari, Colin M. Muir, James Woods, Colten M. McEwan, Katie L. Pennington
Supplementary Data from SGK2, 14-3-3, and HUWE1 Cooperate to Control the Localization, Stability, and Function of the Oncoprotein PTOV1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0fd2530ec18e4c0a4f29f3de7cdca194
https://doi.org/10.1158/1541-7786.22527332
https://doi.org/10.1158/1541-7786.22527332
Autor:
Joshua L. Andersen, Manabu Kurokawa, Stephen R. Piccolo, Katherine K. McCormack, Tyler Heaton, Sandeep Kaur, Christina M. Egbert, Eranga R. Balasooriya, Riley Eastmond, A.G. Pramoda Sahankumari, Colin M. Muir, James Woods, Colten M. McEwan, Katie L. Pennington
PTOV1 is an oncogenic protein, initially identified in prostate cancer, that promotes proliferation, cell motility, and invasiveness. However, the mechanisms that regulate PTOV1 remain unclear. Here, we identify 14-3-3 as a PTOV1 interactor and show
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d6fdb6793264658472e0f6cde850d6ff
https://doi.org/10.1158/1541-7786.c.6545390.v1
https://doi.org/10.1158/1541-7786.c.6545390.v1
Autor:
Vinita Bharat, Roeland Vanhauwaert, Li Li, Colin M. Muir, Aarooran Sivakumaran Durairaj, Sujyoti Chandra, Yann Le Guen, Pawan Nandakishore, Chung-Han Hsieh, Stefano E. Rensi, Russ B. Altman, Michael D. Greicius, Liang Feng, Xinnan Wang
SummaryGenetic backgrounds and risk factors among individuals with Parkinson’s disease (PD) are highly heterogenous, limiting our ability to effectively detect and treat PD. Here we connect several potential PD risk genes and elements to one biolog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5fa9d116fea8e0e315ce47a47b7de7fd
https://doi.org/10.1101/2022.10.30.513580
https://doi.org/10.1101/2022.10.30.513580
Autor:
Katie L. Pennington, Colten M. McEwan, James Woods, Colin M. Muir, A G Pramoda Sahankumari, Riley Eastmond, Eranga R. Balasooriya, Christina M. Egbert, Katherine K. McCormack, Joshua L. Andersen
Publikováno v:
Cancer Research. 82:1469-1469
Cells must respond to changing environments by modulating signaling and gene expression patterns to maintain homeostasis, health, and viability. Inappropriate responses lead to disease processes, such as cancer. Despite improvements in targeted treat